Formula

Gui Shao Di Huang Tang

歸芍地黃湯

Also known as:

Gui Shao Di Huang Wan (归芍地黄丸, pill form from Jǐng Yuè Quán Shū) , Dang Gui Shao Yao Di Huang Tang

Properties

Yin-tonifying formulas · Slightly Warm

Key Ingredients

Shu Di Huang

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula that nourishes the Liver and Kidneys, replenishes Blood, and clears mild deficiency Heat. It is commonly used for dizziness, tinnitus, dry throat, afternoon tidal fever, lower back and leg soreness, and menstrual irregularities caused by combined Liver and Kidney weakness with insufficient Blood and Yin.

Formula Category

Main Actions

  • Nourishes Liver and Kidney Yin
  • Nourishes Blood
  • Nourishes Blood and Softens the Liver
  • Clears Deficiency Heat
  • Nourishes Yin and Blood

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Gui Shao Di Huang Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Gui Shao Di Huang Tang addresses this pattern

When the Liver and Kidneys become depleted of Yin, the body loses its ability to moisten, cool, and anchor its internal functions. The Kidneys, as the root of Yin for the entire body, fail to nourish the Liver, and the Liver in turn cannot properly store Blood or keep its Yang in check. This manifests as dizziness, tinnitus, dry eyes, soreness in the lower back and knees, and a sensation of Heat in the afternoon or at night (when Yin is naturally at its lowest). Gui Shao Di Huang Tang addresses this through its core Liu Wei Di Huang Wan structure, which nourishes Kidney Yin and clears deficiency Heat through its balanced "three supplement, three drain" architecture. The addition of Dang Gui and Bai Shao strengthens this approach by also replenishing Liver Blood, recognizing that in clinical reality, Liver-Kidney Yin deficiency almost always involves some degree of Blood insufficiency. The formula thereby restores the Yin-Blood foundation that the Liver and Kidneys share.

A practitioner would look for one or more of these signs

Dizziness

Especially with a sense of lightheadedness upon standing

Tinnitus

Low-pitched ringing or buzzing in the ears

Lower Back Pain

Soreness and weakness in the lower back and knees

Night Sweats

Sweating during sleep due to Yin failing to contain fluids

Dry Mouth

Dry throat, especially in the afternoon or evening

Insomnia

Difficulty sleeping due to deficiency Heat disturbing the spirit

How It Addresses the Root Cause

Gui Shao Di Huang Tang addresses a pattern of combined Liver and Kidney Yin deficiency with concurrent Blood insufficiency. In TCM theory, the Kidneys store Essence (Jing) and are the root of Yin for the entire body, while the Liver stores Blood and depends on Kidney Yin to nourish it. When Kidney Yin becomes depleted through chronic illness, overwork, emotional strain, or the natural aging process, the Liver loses its source of nourishment. The Liver then fails to store Blood adequately, and Liver Blood becomes deficient alongside Kidney Yin.

This dual deficiency produces a characteristic cluster of symptoms. Insufficient Yin means the cooling, moistening aspect of the body is weakened, allowing empty Heat (deficiency Heat) to rise. This manifests as afternoon tidal fevers, night sweats, dry mouth and throat, and a flushed feeling. Meanwhile, Blood deficiency leads to poor nourishment of the head, eyes, and Heart: dizziness, blurred vision, heart palpitations, insomnia, and a pale or sallow complexion appear. In women, Liver Blood deficiency commonly disrupts menstruation, leading to scanty periods, delayed cycles, or amenorrhea. The Yin deficiency at the root level also weakens the lower back and knees (the domain of the Kidneys), producing soreness and weakness in those areas, as well as heel pain.

Because the Liver and Kidneys share a common Yin source (a classical principle known as "Liver and Kidney share the same origin," or gān shèn tóng yuán 肝肾同源), deficiency in one organ inevitably affects the other. The formula works by replenishing Kidney Yin at its source while simultaneously nourishing Liver Blood, thereby addressing both the root cause and its downstream consequences.

Formula Properties

Temperature

Slightly Warm

Taste Profile

Predominantly sweet and sour with mild bitter notes. Sweet to tonify and nourish, sour to astringently preserve Yin and Blood, and mildly bitter to clear Deficiency Heat.

Target Organs
Liver Kidneys Spleen
Channels Entered
Liver Kidney Spleen

Formula Origin

Zhèng Yīn Mài Zhì (《症因脉治》Pathology, Causes, Pulse, and Treatment), Volume 2, by Qin Jingming (秦景明), Qīng dynasty

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Gui Shao Di Huang Tang

Detailed information about each herb in Gui Shao Di Huang Tang and their roles

Kings
Deputies
Assistants
Envoys
Shu Di Huang
Shu Di Huang

Prepared Rehmannia root

Dosage: 15 - 24g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Gui Shao Di Huang Tang

As the chief herb at the highest dosage, Sheng Di Huang nourishes Yin, cools Blood, and generates fluids. It replenishes the depleted Kidney and Liver Yin that forms the root of this pattern, while its cooling nature helps clear deficiency Heat.

Dang Gui
Dang Gui

Chinese Angelica root

Dosage: 9 - 12g

Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen
Parts Used Root (根 gēn)
Role in Gui Shao Di Huang Tang

Nourishes and activates Blood, softens the Liver, and supports the generation of new Blood. Together with Bai Shao, it extends the formula beyond pure Yin nourishment into Blood-level nourishment, making it especially suitable when Blood deficiency accompanies Yin deficiency.

Bai Shao
Bai Shao

White peony root

Dosage: 9 - 12g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen
Parts Used Root (根 gēn)
Role in Gui Shao Di Huang Tang

Nourishes Blood and preserves Yin, softens the Liver and restrains Liver Yang. It works alongside Dang Gui to strengthen Blood-nourishing capacity and helps prevent the rising of unanchored Yang that can cause dizziness and headache when Yin is depleted.

Shan Zhu Yu
Shan Zhu Yu

Asiatic cornelian cherry fruit

Dosage: 9 - 12g

Temperature Slightly Warm
Taste Sour (酸 suān), Astringent (涩 sè)
Organ Affinity Liver, Kidneys
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Gui Shao Di Huang Tang

Nourishes and astringes the Liver and Kidneys, secures the essence (Jing). Its sour and warm nature helps consolidate Kidney Yin and prevent further leakage of vital substances.

Shan Yao
Shan Yao

Chinese yam

Dosage: 9 - 12g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs, Kidneys
Parts Used Rhizome (根茎 gēn jīng)
Role in Gui Shao Di Huang Tang

Tonifies the Spleen and nourishes the Kidneys. By strengthening the Spleen, it supports the digestive system's role in generating Blood and Qi, providing a foundation for the nourishing herbs to build upon.

Mu Dan Pi
Mu Dan Pi

Tree peony root bark

Dosage: 6 - 9g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Heart, Liver, Kidneys
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Gui Shao Di Huang Tang

Clears Heat from the Liver, cools Blood, and mildly invigorates Blood circulation. It restrains the warmth of Shan Zhu Yu and helps clear any deficiency Heat that arises from Yin depletion.

Fu Ling
Fu Ling

Poria

Dosage: 6 - 9g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Gui Shao Di Huang Tang

Strengthens the Spleen and drains Dampness through gentle diuresis. It prevents the rich, cloying nourishing herbs from creating stagnation, and supports Shan Yao in protecting digestive function.

Ze Xie
Ze Xie

Water plantain rhizome

Dosage: 6 - 9g

Temperature Cold
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Kidneys, Urinary Bladder
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Gui Shao Di Huang Tang

Drains Kidney turbidity and clears Damp-Heat from the Lower Burner through urination. It prevents the heavy nourishing nature of Sheng Di Huang from becoming overly cloying and directs the formula's action downward to the Kidneys.

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Traditionally taken on an empty stomach with warm water or lightly salted warm water (淡盐汤), typically 30 to 60 minutes before meals, morning and evening.

Typical Duration

Often taken for 4 to 8 weeks as a course of treatment, then reassessed by a practitioner. May be used longer for chronic deficiency conditions with periodic breaks.

Dietary Advice

Avoid excessively greasy, fried, and heavy foods that may impair the Spleen's ability to transform and transport the formula's rich, nourishing ingredients. Limit cold and raw foods (ice cream, raw salads, cold drinks) which can weaken the Spleen and counteract the formula's tonifying effects. Favor warm, easily digestible foods such as congee, soups, steamed vegetables, and lightly cooked dark leafy greens. Foods that nourish Blood and Yin are supportive: black sesame seeds, goji berries, dark grapes, mulberries, eggs, and bone broth. Avoid excessive consumption of spicy, hot foods and alcohol, which can generate Heat and further deplete Yin.

Special Populations

Pregnancy

Use with caution during pregnancy and only under the guidance of a qualified practitioner. While the formula does not contain strongly prohibited herbs, Dang Gui (Chinese Angelica) has mild Blood-moving properties that could theoretically stimulate uterine activity. Mu Dan Pi (Moutan bark) is also traditionally used with caution in pregnancy due to its Blood-cooling and mildly Blood-moving nature. The formula is not absolutely contraindicated, but its use must be carefully evaluated against the individual's clinical needs.

Breastfeeding

There is insufficient evidence to confirm absolute safety during breastfeeding. The formula's ingredients are generally considered mild, and Shu Di Huang (prepared Rehmannia) and Dang Gui (Chinese Angelica) have a long tradition of postpartum use in TCM to replenish Blood. However, because the formula contains Ze Xie (Alisma), which promotes urination and may theoretically affect fluid balance and milk production, and because data on the transfer of active compounds through breast milk is lacking, breastfeeding mothers should only use this formula under professional guidance.

Pediatric Use

This formula is not commonly prescribed for young children and is more suited to adolescents and adults. If used in children (generally over age 6), dosages should be reduced to approximately one-third to one-half of the adult dose, adjusted by the child's age and body weight. Children and adolescents should only take this formula under the supervision of a qualified practitioner. The cloying, rich nature of Shu Di Huang may cause digestive upset in children with weak digestion.

Drug Interactions

Antihypertensive medications: Shu Di Huang (Rehmannia) has demonstrated mild blood-pressure-lowering effects in pharmacological studies. Combined use with antihypertensive drugs may produce an additive hypotensive effect, requiring blood pressure monitoring.

Antidiabetic medications: Rehmannia oligosaccharides have shown hypoglycemic activity in preclinical studies. Patients taking insulin or oral hypoglycemic agents should monitor blood sugar closely, as additive effects on blood glucose are possible.

Anticoagulant and antiplatelet drugs: Dang Gui (Chinese Angelica) contains ligustilide and ferulic acid, which have mild anticoagulant and Blood-moving properties. Concurrent use with warfarin, heparin, aspirin, or other blood thinners may increase bleeding risk.

Immunosuppressants: Rehmannia extracts have shown immunomodulatory activity. Patients taking immunosuppressive medications (e.g., cyclosporine, tacrolimus) should exercise caution, as the formula may alter immune function in unpredictable ways.

Diuretics: Ze Xie (Alisma) has mild diuretic properties. Combined use with pharmaceutical diuretics could lead to excessive fluid loss or electrolyte imbalances.

Contraindications

Caution

Spleen and Stomach deficiency with poor digestion, loose stools, or reduced appetite. The rich, cloying nature of Shu Di Huang (prepared Rehmannia) and the formula's overall Yin-nourishing character can further impair digestive function in those with weak Spleen Qi.

Caution

Patterns of excess Dampness, Phlegm-Damp accumulation, or significant fluid retention. The heavy, moistening herbs in this formula (particularly Shu Di Huang and Dang Gui) can worsen Dampness. If Dampness is present, the formula requires modification or should be avoided.

Caution

Yang deficiency with pronounced Cold signs such as cold extremities, clear profuse urination, and a pale tongue with white coating. This formula is designed for Yin and Blood deficiency and does not warm Yang. Use of Yin-enriching formulas in true Yang deficiency can further damage Yang.

Caution

Exterior pathogen invasion (common cold or flu) that has not been resolved. Tonifying formulas should generally not be used while an external pathogen is still active, as they can trap the pathogen inside the body.

Avoid

Known allergy or hypersensitivity to any of the eight herbs in the formula.

Cautions & Warnings

Gui Shao Di Huang Wan is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with this formula.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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Treasure of the East

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