Formula

Gui Ling Gan Lu Yin

桂苓甘露飲

Also known as:

Gui Ling Gan Lu San (桂苓甘露散) , Gui Ling Bai Zhu San (桂苓白术散)

Properties

Summer-Heat-clearing formulas · Cool

Key Ingredients

Hua Shi

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula designed for hot summer conditions where both Heat and Dampness accumulate in the body. It helps clear internal Heat, relieve thirst and irritability, and promote urination to drain excess Dampness. It is especially suited for summertime illness with fever, headache, digestive upset (vomiting and diarrhea), and reduced or dark urine.

Formula Category

Main Actions

  • Clears Summer-Heat
  • Clears Heat
  • Promotes Urination and Drains Dampness
  • Transforms Qi and facilitates the resolution of Dampness
  • Strengthens the Spleen
  • Warms Yang and Transforms Qi

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Gui Ling Gan Lu Yin is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Gui Ling Gan Lu Yin addresses this pattern

This is the primary pattern this formula addresses. In hot, humid summer conditions, Summerheat (a Yang pathogenic factor) combines with Dampness (a Yin pathogenic factor) to invade the body. The Summerheat generates internal Heat, causing fever, thirst, and irritability, while the Dampness obstructs Qi flow and impairs fluid metabolism, leading to reduced urination, heaviness, and digestive disturbance. The formula's three cold minerals (Hua Shi, Shi Gao, Han Shui Shi) powerfully clear the Summerheat, while the Wu Ling San component (Fu Ling, Zhu Ling, Ze Xie, Bai Zhu, Rou Gui) transforms Qi and drains Dampness through urination. Gan Cao and Hua Shi together (Liu Yi San) specifically target Summerheat resolution. This formula is particularly suited when the Heat component is more pronounced than the Dampness, or when both are equally severe.

A practitioner would look for one or more of these signs

Fever

Fever due to Summerheat invasion

Headaches

Headache with sensation of heaviness

Excessive Thirst

Intense thirst with desire to drink

Irritability

Restlessness and irritability from Heat

Difficult Urination

Scanty, dark, or painful urination

Diarrhea

Watery diarrhea or cholera-like vomiting and diarrhea

Nausea Or Vomiting

Vomiting with simultaneous diarrhea (sudden turmoil disorder)

How It Addresses the Root Cause

Gui Ling Gan Lu Yin addresses a condition where external Summer-Heat invades the body and combines with internal Dampness, creating a complex pattern of Heat and stagnant fluids. In TCM theory, the intense heat of summer can overwhelm the body's ability to regulate its temperature and fluid metabolism. When a person is exposed to Summer-Heat and then drinks large amounts of cold fluids to quench their thirst, the Spleen and Stomach (the digestive organs responsible for transforming and transporting fluids) become overwhelmed. The fluids accumulate internally rather than being properly distributed and excreted.

This creates a dual pathology: Heat from the Summer-Heat lodges in the Qi level, producing fever, irritability, and intense thirst, while stagnant water and Dampness obstruct the normal flow of Qi, blocking urination and disrupting the Stomach's descending function. When the Stomach Qi rebels upward, vomiting occurs; when turbid Dampness pours downward, diarrhea results. In severe cases, both happen simultaneously, a condition classical texts call "sudden turmoil disorder" (霍乱 huo luan). The Bladder's Qi transformation function is impaired, so urine output decreases even as the person keeps drinking, creating a vicious cycle of fluid accumulation.

The formula works because it simultaneously addresses both the Heat and the Dampness. It clears Summer-Heat from the Qi level while opening the waterways to drain accumulated fluids through urination, restoring the normal ascending-descending movement of Qi in the middle burner. The small amount of warming Cinnamon ensures that the cold minerals do not freeze the Qi mechanism, keeping the body's fluid transformation active even while clearing Heat.

Formula Properties

Temperature

Cool

Taste Profile

Predominantly bland and sweet with a cool, mineral quality — bland to drain Dampness through urination, sweet to protect the Stomach, and mineral-cool to clear Summer-Heat.

Target Organs
Stomach Urinary Bladder Spleen Lungs
Channels Entered
Stomach Bladder Spleen Lung

Formula Origin

Huang Di Su Wen Xuan Ming Lun Fang (黄帝素问宣明论方) by Liu Wansu (刘完素)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Gui Ling Gan Lu Yin

Detailed information about each herb in Gui Ling Gan Lu Yin and their roles

Kings
Deputies
Assistants
Envoys
Hua Shi
Hua Shi

Talcum

Dosage: 12 - 18g

Temperature Cold
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Stomach, Urinary Bladder
Parts Used Mineral (矿物 kuàng wù)
Role in Gui Ling Gan Lu Yin

The principal herb in the formula, used in the largest dose. Hua Shi clears Summerheat and drains Damp-Heat downward through the urine, directly addressing both the Heat and Dampness that are the core pathogenic factors in this pattern.

Shi Gao
Shi Gao

Gypsum

Dosage: 9 - 15g

Temperature Cold
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Lungs, Stomach
Parts Used Mineral (矿物 kuàng wù)
Role in Gui Ling Gan Lu Yin

Clears Heat and drains Fire from the Qi level, powerfully relieving fever, thirst, and irritability. Works alongside Hua Shi and Han Shui Shi as one of the 'three stones' (san shi) to clear Heat from the six bowels.

Han Shui Shi
Han Shui Shi

Calcite / Red Gypsum

Dosage: 9 - 15g

Temperature Cold
Taste Acrid / Pungent (辛 xīn), Salty (咸 xián)
Organ Affinity Heart, Stomach, Kidneys
Parts Used Mineral (矿物 kuàng wù)
Role in Gui Ling Gan Lu Yin

Clears Heat and drains Fire, reinforcing the cooling power of Shi Gao. Together with Shi Gao and Hua Shi, it forms the 'three stones' grouping that provides the formula's strong Heat-clearing action.

Fu Ling
Fu Ling

Poria

Dosage: 9 - 15g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Gui Ling Gan Lu Yin

Strengthens the Spleen and promotes urination to drain Dampness. As part of the Wu Ling San component within this formula, Fu Ling supports the transformation and transportation of fluids.

Zhu Ling
Zhu Ling

Polyporus

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Kidneys, Urinary Bladder
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Gui Ling Gan Lu Yin

Promotes urination and drains Dampness, complementing Fu Ling and Ze Xie. Together these diuretic herbs ensure Dampness is expelled through the urinary pathway.

Ze Xie
Ze Xie

Water plantain rhizome

Dosage: 6 - 10g

Temperature Cold
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Kidneys, Urinary Bladder
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Gui Ling Gan Lu Yin

Promotes urination and drains Dampness from the lower burner, directly reaching the Kidney and Bladder to facilitate fluid metabolism.

Bai Zhu
Bai Zhu

White Atractylodes rhizome

Dosage: 3 - 6g

Temperature Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Spleen, Stomach
Parts Used Rhizome (根茎 gēn jīng)
Role in Gui Ling Gan Lu Yin

Strengthens the Spleen and dries Dampness, supporting the body's ability to transform and transport fluids. Helps prevent Dampness from accumulating again by supporting the root of fluid metabolism.

Rou Gui
Rou Gui

Cinnamon bark

Dosage: 1.5 - 3g

Temperature Hot
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Heart, Liver, Spleen, Kidneys
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Gui Ling Gan Lu Yin

Warms Yang and promotes Qi transformation to assist the Bladder in transforming fluids. Its warming nature helps counterbalance the large amount of cold minerals in the formula and prevents the cold herbs from congealing Dampness. A small dose is used strategically.

Gan Cao
Gan Cao

Licorice root

Dosage: 6 - 10g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Gui Ling Gan Lu Yin

Harmonizes the actions of the diverse formula ingredients and protects the Middle Burner. Together with Hua Shi it forms the Liu Yi San (Six-to-One Powder) within this formula, clearing Summerheat and augmenting Qi.

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Between meals, 2–3 times daily. In acute Summer-Heat illness with vomiting and diarrhea, small frequent doses throughout the day are preferred.

Typical Duration

Acute use: 1–5 days, discontinued once symptoms resolve. Not intended for long-term use.

Dietary Advice

While taking this formula, avoid greasy, fried, and heavy foods that generate Dampness and burden the Spleen. Cold, raw foods and excessive iced drinks should also be avoided, as they can impair the Spleen's Qi transformation despite the formula's cooling nature. Light, easily digestible foods such as rice porridge (congee), mung bean soup, and winter melon are supportive. Avoid alcohol and spicy, hot foods that may intensify internal Heat. Adequate fluid intake with warm or room-temperature water is important to support urination and prevent dehydration, especially during summer illness with vomiting and diarrhea.

Special Populations

Pregnancy

Use with caution during pregnancy. Hua Shi (Talcum) and Ze Xie (Alisma) are strongly draining and diuretic, which may deplete fluids needed during pregnancy. Han Shui Shi (Glauberite) and Shi Gao (Gypsum) are cold in nature and may adversely affect the Spleen Yang, which is already under strain during pregnancy. Zhu Ling (Polyporus) adds further diuretic action. While none of these herbs are classically listed as abortifacient, the overall strongly draining and cold nature of this formula makes it unsuitable for routine use in pregnant women. If Summer-Heat illness occurs during pregnancy, a qualified practitioner should carefully weigh the risks and modify the formula accordingly.

Breastfeeding

No specific classical prohibitions exist for use during breastfeeding. However, the formula's strongly draining and diuretic nature (from Hua Shi, Ze Xie, Fu Ling, and Zhu Ling) could theoretically reduce fluid volume and potentially affect milk production. The cold minerals (Shi Gao, Han Shui Shi) may also be a concern as their effect on breast milk composition is unknown. Gan Cao (Licorice) contains glycyrrhizin which can pass into breast milk. This formula is intended for short-term acute use in Summer-Heat conditions, so brief use under practitioner supervision is reasonable, but prolonged use should be avoided during lactation.

Pediatric Use

Classical texts specifically note that this formula can be used for children experiencing summer vomiting, diarrhea, and fright Wind (小儿吐泻、惊风). Dosages should be reduced significantly based on age and body weight, typically to one-third to one-half of the adult dose for children over 6 years, and one-quarter for younger children. The formula should be given in smaller, more frequent doses rather than large single doses. Because the formula contains strongly draining minerals and diuretic herbs, careful monitoring of fluid intake and hydration status is essential in pediatric use. For infants under 1 year, this formula is generally not recommended without close practitioner supervision.

Drug Interactions

Gan Cao (Licorice Root): Glycyrrhizin in Gan Cao can cause pseudoaldosteronism (sodium retention, potassium loss, elevated blood pressure). It may interact with antihypertensive medications, diuretics (especially potassium-depleting types like thiazides and loop diuretics, compounding potassium loss), corticosteroids (additive mineralocorticoid effects), and digoxin/cardiac glycosides (hypokalemia increases toxicity risk).

Diuretic herbs (Fu Ling, Zhu Ling, Ze Xie, Hua Shi): The combined diuretic effect of these four herbs may potentiate pharmaceutical diuretics, increasing the risk of dehydration and electrolyte imbalance. Caution is warranted when co-administered with thiazide or loop diuretics. Ze Xie (Alisma) has demonstrated lipid-lowering effects in some studies and may theoretically interact with statin medications.

Mineral herbs (Shi Gao, Han Shui Shi, Hua Shi): These calcium- and sulfate-containing minerals may interfere with the absorption of tetracycline antibiotics, fluoroquinolones, and bisphosphonates if taken simultaneously. A two-hour separation between doses is advisable.

Contraindications

Avoid

Yin Deficiency with Heat signs (dry mouth, night sweats, red tongue with little coating). The cold, draining minerals and diuretic herbs in this formula can further deplete Yin fluids.

Avoid

Cold-Dampness without Heat. This formula is designed for Summer-Heat combined with Dampness. If there is only Cold-Dampness without any Heat component, the cold-natured minerals (Shi Gao, Han Shui Shi, Hua Shi) will worsen the condition.

Caution

Spleen and Stomach Yang Deficiency with cold signs (cold limbs, watery stools, pale tongue). The large dose of cold minerals may further damage Yang Qi.

Caution

Excessive sweating or severe fluid depletion. The diuretic action of multiple water-draining herbs (Fu Ling, Zhu Ling, Ze Xie, Hua Shi) can worsen dehydration.

Caution

Chronic, debilitated patients with Qi Deficiency. The formula is designed for acute Summer-Heat illness in relatively robust individuals, not for prolonged tonification.

Cautions & Warnings

Gui Ling Gan Lu Yin is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Gui Ling Gan Lu Yin.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Treasure of the East

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