Formula

Bei Mu Gua Lou San

Fritillaria & Trichosanthes Formula | 贝母瓜蒌散

Also known as:

Fritillary bulbs and Snake gourds Powder , Fritillaria and Trichosanthes Fruit Powder

Properties

Phlegm-resolving formulas · Cool

Key Ingredients

Chuan Bei Mu, Gua Lou

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula for dry, stubborn coughs where thick, sticky phlegm is hard to bring up and the throat feels dry and sore. It gently moistens the Lungs and loosens phlegm without the harsh drying effects of many cough remedies, making it especially suited for coughs caused by dryness and mild heat in the respiratory system.

Formula Category

Main Actions

  • Moistens the Lungs and clears Heat
  • Resolves Phlegm
  • Moves Qi
  • Stops Cough
  • Generates Fluids

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Bei Mu Gua Lou San is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Bei Mu Gua Lou San addresses this pattern

Dry-Phlegm in the Lungs (燥痰) arises when dryness or heat scorches the Lung's fluids, thickening them into viscous, sticky phlegm that is difficult to cough up. As the classical commentary in the Cheng Fang Bian Du puts it, this is a condition where "fire scorches the Lung metal, and fluids are burned into phlegm." The airways become dry and irritated, yet paradoxically congested with thick, tenacious mucus that the body cannot clear.

Bei Mu Gua Lou San is the representative formula for this pattern. The paired chief herbs, Chuan Bei Mu (Fritillaria) and Gua Lou (Trichosanthes fruit), work together to moisten the Lung while dissolving and clearing the sticky phlegm. Tian Hua Fen (Trichosanthes root) reinforces this by generating fluids and cooling residual heat. Crucially, the formula also includes small amounts of Ju Hong (red tangerine peel) and Fu Ling (Poria), which gently regulate Qi and strengthen the Spleen's fluid metabolism to address the root of phlegm production, while Jie Geng (Platycodon) opens the Lung Qi and guides the other herbs upward to the Lung. The formula is carefully balanced: it moistens without creating more phlegm, and dissolves phlegm without further drying the Lung.

A practitioner would look for one or more of these signs

Hypochondrial Pain That Is Worse On Coughing And Breathing

Choking, paroxysmal cough that is difficult to suppress

Difficult to Expectorate Phlegm

Thick, sticky phlegm that is scanty and hard to cough up

Dry Throat

Dry, scratchy throat with possible soreness or a feeling of obstruction

Dry Mouth

Dry mouth from depleted fluids

Wheezing

Wheezing or shortness of breath from phlegm blocking the airways

How It Addresses the Root Cause

The Lungs are considered a delicate organ that depends on adequate moisture to function smoothly. When pathological Heat (either from an external warm-dry pathogen or from internal sources) affects the Lungs, it "scorches" the body's normal fluids, thickening them into a sticky, viscous Phlegm that is difficult to cough up. This is what TCM calls Dry Phlegm (燥痰, zào tán).

Because the Lungs' fluids have been partially consumed by Heat, the airways become parched. The throat feels dry and scratchy, and the remaining Phlegm clings stubbornly to the airway walls, resisting expectoration. At the same time, the Lungs' natural descending and dispersing action is obstructed by this viscous Phlegm, causing coughing, wheezing, and a sensation of constriction in the chest. The tongue coating is typically white but dry (not moist), reflecting Dryness rather than true fluid depletion, and the pulse tends to be rapid, indicating residual Heat.

The key distinction is that this is not full-blown Yin Deficiency. The body's deeper reserves of Yin are still intact; the problem is localised Lung Dryness with Heat-generated Phlegm. Therefore the correct strategy is to moisten the Lungs and clear the Heat while simultaneously dissolving the Phlegm and restoring normal Qi movement, rather than deeply nourishing Yin with heavy, cloying substances that could paradoxically worsen the Phlegm.

Formula Properties

Temperature

Cool

Taste Profile

Predominantly bitter and sweet with mild blandness. The bitter clears Heat and directs downward, the sweet moistens dryness and generates fluids, and the bland component gently drains dampness to prevent phlegm accumulation.

Target Organs
Lungs Spleen Stomach
Channels Entered
Lung Stomach Spleen Heart

Formula Origin

Yi Xue Xin Wu (醫學心悟, Medical Revelations) by Cheng Guopeng (程國彭)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Bei Mu Gua Lou San

Detailed information about each herb in Bei Mu Gua Lou San and their roles

Kings
Deputies
Assistants
Envoys
Chuan Bei Mu
Chuan Bei Mu

Sichuan fritillary bulb

Dosage: 4.5 - 10g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Lungs, Heart
Parts Used Bulb (鳞茎 lín jīng)
Role in Bei Mu Gua Lou San

The primary herb of the formula. Bei Mu (Fritillaria, preferably Chuan Bei Mu) is bitter, sweet, and slightly cold. It clears Heat from the Lungs, moistens dryness, transforms phlegm, and stops coughing. As the herb at the highest dosage, it directly addresses the core problem of dryness-phlegm by both resolving the sticky phlegm and soothing the parched Lung tissue.

Gua Lou
Gua Lou

Trichosanthes fruit

Dosage: 3 - 10g

Temperature Cold
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Stomach, Large Intestine
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Bei Mu Gua Lou San

Gua Lou (Trichosanthes fruit) is sweet, cold, and slightly bitter. It clears and moistens the Lungs, opens the chest, loosens phlegm, and promotes its downward discharge. Working in tandem with Bei Mu as a mutually reinforcing pair (xiangxu), the two together form the classic combination for clearing Lung Heat and transforming dryness-phlegm.

Tian Hua Fen
Tian Hua Fen

Trichosanthes root

Dosage: 2.5 - 10g

Temperature Cool
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Stomach
Parts Used Root (根 gēn)
Role in Bei Mu Gua Lou San

Tian Hua Fen (Trichosanthes root) clears Heat from the Lungs and generates fluids to moisten dryness. It reinforces the King herbs by replenishing the body fluids that have been scorched into phlegm, addressing the root fluid deficiency that sustains the dryness-phlegm cycle.

Fu Ling
Fu Ling

Poria

Dosage: 2.5 - 10g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Bei Mu Gua Lou San

Fu Ling (Poria) strengthens the Spleen and promotes the removal of dampness. Since phlegm originates from impaired fluid metabolism rooted in the Spleen, Fu Ling addresses the source of phlegm production. Its dosage is deliberately kept low so that its drying and draining tendencies do not counteract the moistening strategy of the formula.

Ju Hong
Ju Hong

Red Tangerine Peel

Dosage: 2.5 - 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Spleen
Parts Used Peel / Rind (皮 pí / 果皮 guǒ pí)
Role in Bei Mu Gua Lou San

Ju Hong (tangerine peel outer layer) regulates Qi and transforms phlegm. When Qi flows smoothly, phlegm disperses more easily. Like Fu Ling, it is used in a small dose to contribute its Qi-moving and phlegm-resolving actions without introducing excessive warmth or dryness into the formula.

Jie Geng
Jie Geng

Platycodon root

Dosage: 2.5 - 6g

Temperature Neutral
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Lungs
Parts Used Root (根 gēn)
Role in Bei Mu Gua Lou San

Jie Geng (Platycodon root) opens and disseminates Lung Qi, promotes the expulsion of phlegm, and guides the other herbs upward into the Lung channel. By restoring the Lung's normal descending and dispersing functions, it ensures the formula reaches its target organ effectively.

Modern Research (1 study)

  • Bei Mu Gua Lou San facilitates mucus expectoration by increasing surface area and hydration levels of airway mucus in an air-liquid-interface cell culture model of the respiratory epithelium (In vitro study, 2023)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Twice daily, 30 minutes after meals, as a warm decoction or dissolved granules. Taking it after meals protects the Stomach from the cooling nature of the formula.

Typical Duration

Acute dry cough: 5-10 days. Chronic or recurring Dryness-Phlegm cough: 2-4 weeks, reassessed by a practitioner.

Dietary Advice

While taking this formula, avoid spicy, fried, roasted, and heavily seasoned foods, as these generate Heat and worsen Lung Dryness. Alcohol and tobacco should also be avoided. Cold and raw foods are acceptable in moderation (the formula is cooling, not warming), but excessive cold foods may impair digestion. Favour moistening, nourishing foods such as pears, white fungus (yin er), lily bulb (bai he), honey, loquat, almonds, and congee. Adequate hydration is important. Dairy products should be limited, as they are traditionally considered to promote Phlegm production.

Modern Usage

Bei Mu Gua Lou San is classified as a formula that moistens Dryness and transforms Phlegm. The formula is known for its ability to moisten the Lungs, clear Heat, regulate Qi, and dissolve Phlegm. It is primarily used to treat coughs with dry phlegm, characterized by symptoms such as coughing with sticky, hard-to-expectorate phlegm, dry and sore throat, dry mouth, shortness of breath, and a red tongue with a dry white coating.

In modern clinical practice, this formula is often modified to treat conditions such as pulmonary tuberculosis, pneumonia, acute and chronic bronchitis, and pharyngitis, particularly when these conditions are associated with dryness and heat in the lung meridian, leading to scanty, difficult-to-expectorate phlegm.

Special Populations

Pregnancy

Generally considered low-risk, but caution is advised. Gua Lou (Trichosanthes fruit) has a downward-directing, slightly laxative quality, and Tian Hua Fen (Trichosanthes root) is traditionally noted as a substance that should be used cautiously during pregnancy due to its cold nature and historical use in inducing labour or abortion (when used in concentrated injectable form). In the small doses present in this formula the risk is low, but pregnant individuals should consult a qualified practitioner before use. The formula's overall cooling nature may also be unsuitable for constitutionally cold pregnant patients.

Breastfeeding

No specific classical contraindications for breastfeeding have been recorded. The herbs in this formula are generally mild and food-grade in character. Chuan Bei Mu and Gua Lou are widely used in paediatric and postpartum contexts in China. However, the formula's cooling nature could theoretically affect a nursing mother with weak digestion or cold constitution. If the mother has loose stools or feels cold, the formula should be used with caution or modified. A practitioner should be consulted to ensure appropriateness.

Pediatric Use

This formula has been used clinically in children, including for mycoplasma pneumonia in paediatric patients. Dosages should be reduced according to age and body weight, typically to one-third to one-half of the adult dose for children aged 6-12, and one-quarter for children under 6. The herbs are generally mild, but the cooling nature of the formula means it should be used cautiously in very young children or those with weak digestion. A qualified practitioner should supervise use in children.

Drug Interactions

No well-documented major drug interactions have been established for this specific formula. However, the following theoretical considerations apply:

  • Chuan Bei Mu (Fritillaria) contains steroidal alkaloids that may theoretically interact with cardiac glycosides (e.g. digoxin) or antiarrhythmic drugs, though clinical evidence is lacking.
  • Tian Hua Fen (Trichosanthes root) has been shown to have hypoglycaemic effects in some studies and could theoretically potentiate the action of oral hypoglycaemic agents or insulin. Blood sugar should be monitored in diabetic patients.
  • Fu Ling (Poria) has mild diuretic properties and could theoretically interact with pharmaceutical diuretics, potentially increasing fluid loss.
  • The classical "eighteen incompatibilities" (十八反) state that Bei Mu is incompatible with Wu Tou (Aconitum). Any concurrent use of Aconite-containing preparations is strictly contraindicated.

Contraindications

Avoid

Cough due to Yin Deficiency with internal Heat (symptoms such as dry cough with no phlegm, night sweats, tidal fever, five-centre heat). This formula treats Dryness-Phlegm, not true Yin Deficiency. Yin-nourishing formulas like Mai Men Dong Tang or Bai He Gu Jin Tang are more appropriate.

Avoid

Cough due to Kidney Yin Deficiency with deficiency Fire flaring upward (Kidney failing to grasp Qi, with dry throat, wheezing, and weak lower back). As the Yi Xue Xin Wu itself states, this formula should not be used for such presentations.

Avoid

Cough with copious thin, watery, white sputum indicating Cold-Phlegm or Damp-Phlegm from Spleen Yang Deficiency. This formula is cooling and moistening and would worsen this pattern.

Caution

Patients with pronounced Spleen deficiency and poor digestion. The cold, moistening nature of the chief herbs (Chuan Bei Mu, Gua Lou, Tian Hua Fen) can impair Spleen function. If needed, the formula should be modified with stronger Spleen-supporting herbs.

Caution

External Wind-Cold invasion with predominant chills and thin white phlegm. This formula does not release the exterior and may trap the pathogen inside. Treat the exterior first.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Treasure of the East

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