Formula

Bai Tou Weng Tang

Pulsatilla Decoction | 白头翁汤

Also known as:

Anemone Combination

Properties

Heat-clearing formulas · Cold

Key Ingredients

Bai Tou Weng

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula from the Shang Han Lun used to treat severe intestinal infections with bloody diarrhea, abdominal pain, and an urgent need to use the toilet. It works by clearing intense Heat and toxins from the intestines and cooling the Blood to stop the bleeding. It is most commonly applied to acute dysentery and active flares of inflammatory bowel conditions when Heat is the dominant factor.

Formula Category

Main Actions

  • Clears Heat and Resolves Toxicity
  • Cools the Blood
  • Stops Dysentery
  • Clears Damp-Heat from the Lower Burner
  • Dries Dampness in the Intestines

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Bai Tou Weng Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Bai Tou Weng Tang addresses this pattern

This is the primary pattern for which the formula was designed. Heat-toxin has penetrated deep into the Blood level and descended into the Large Intestine, where it damages the blood vessels and tissue of the intestinal wall. The toxic Heat scorches the Qi and Blood in the gut, causing them to decompose into pus and blood. Because the toxin resides primarily in the Blood level rather than the Qi level, the discharge is predominantly bloody (more red than white). The Heat-toxin also obstructs the free flow of Qi in the intestines, producing the characteristic tenesmus (a painful, urgent need to defecate that brings little relief). Bai Tou Weng Tang directly addresses this mechanism: the King herb clears Blood-level Heat-toxin, the Deputies dry Dampness and resolve toxin in the gut, and Qin Pi astringes the intestines to control the bloody discharge.

A practitioner would look for one or more of these signs

Dysentery

Bloody dysentery with more blood than mucus (赤多白少)

Abdominal Pain

Abdominal pain with tenesmus (里急后重)

Anal Burning

Burning sensation at the anus during defecation

Bloody Stool

Stool containing pus and blood

Thirst

Thirst with desire to drink water, indicating internal Heat

How It Addresses the Root Cause

This formula addresses a condition where toxic Heat has penetrated deep into the Blood level of the intestines. The underlying disease logic in TCM terms runs as follows: when Heat-toxin (a severe, virulent form of pathogenic Heat) invades the body, it can descend into the Large Intestine and scorch the blood vessels of the intestinal lining. The Heat burns through the delicate network of vessels in the gut wall, causing blood and tissue fluid to leak into the stool, which is why the stools contain blood and pus, with blood predominating.

The Heat also creates a blockage in the normal flow of Qi through the intestines. Qi should move smoothly downward for healthy elimination, but when Heat and toxic material clog the intestinal tract, the Qi becomes obstructed. This produces the hallmark symptom of tenesmus (a cramping, urgent, bearing-down sensation with the persistent feeling of needing to defecate but being unable to fully evacuate). The abdominal pain, burning sensation at the anus, thirst, red tongue with yellow coating, and rapid wiry pulse all point to intense Heat lodged in the interior.

In the framework of the Shang Han Lun, this pattern belongs to the Jueyin (terminal Yin) stage, where Heat has entered the deepest Yin level. The classical commentary explains this as Jueyin Heat causing the Liver channel's fire to descend and scald the Large Intestine, since the Liver and Large Intestine share a deep interior-exterior relationship through the Jueyin-Yangming axis. Because the toxin has reached the Blood level, simply drying Dampness or moving Qi is not enough. The treatment must directly clear the Heat-toxin from the Blood, cool the damaged vessels, and dry the Dampness that accompanies the Heat in the intestines.

Formula Properties

Temperature

Cold

Taste Profile

Predominantly bitter with slight astringency. The bitter taste clears Heat and dries Dampness, while the astringency from Qin Pi helps check the downward discharge of fluids and blood.

Target Organs
Large Intestine Liver Stomach
Channels Entered
Large Intestine Liver Stomach Kidney

Formula Origin

Shang Han Lun (傷寒論, Treatise on Cold Damage) by Zhang Zhongjing

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Bai Tou Weng Tang

Detailed information about each herb in Bai Tou Weng Tang and their roles

Bai Tou Weng
Bai Tou Weng

Chinese Pulsatilla root

Dosage: 15g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Stomach, Large Intestine
Parts Used Root (根 gēn)
Role in Bai Tou Weng Tang

The principal herb of the formula. Bitter and cold in nature, it enters the Large Intestine and Liver channels, where it powerfully clears Heat-toxin from the Blood level and stops dysentery. It is the foremost herb for treating hot, bloody dysentery.

Huang Lian
Huang Lian

Coptis rhizome

Dosage: 6g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Stomach, Large Intestine, Gallbladder, Spleen
Parts Used Rhizome (根茎 gēn jīng)
Role in Bai Tou Weng Tang

Bitter and cold, it drains Fire, resolves toxin, and dries Dampness while strengthening the intestinal wall (a classical action described as 'thickening the intestines'). It is one of the most important herbs for treating dysentery and assists the King herb in clearing Heat-toxin.

Huang Qi
Huang Qi

Astragalus root

Dosage: 12g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs
Parts Used Root (根 gēn)
Role in Bai Tou Weng Tang

Bitter and cold, it specifically clears Damp-Heat from the Lower Burner. Working alongside Huang Lian, it reinforces the ability of the King herb to dry Dampness and stop dysentery, with a particular affinity for clearing Heat from the intestines and the lower body.

Qin Pi
Qin Pi

Ash bark

Dosage: 12g

Temperature Cold
Taste Bitter (苦 kǔ), Astringent (涩 sè)
Organ Affinity Liver, Gallbladder, Large Intestine
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Bai Tou Weng Tang

Bitter, cold, and astringent in nature, it clears Heat and resolves toxin while its astringent quality helps bind the intestines and control the dysenteric discharge. Because the condition involves significant bloody stool, this astringent action is especially valuable for stopping the bleeding and diarrhea without trapping the pathogen inside.

Modern Research (4 studies)

  • Systematic review: Chinese herbal medicines in the treatment of ulcerative colitis (2022)
  • Preclinical study: BTWT ameliorates DSS-induced ulcerative colitis via gut microbiota and bile acid regulation (2021)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

On an empty stomach or between meals, served warm. The original text instructs to take one dose warm, and if symptoms do not improve, take a second dose.

Typical Duration

Acute use: 3 to 7 days. This formula is designed for active, acute Heat-toxin dysentery and should be reassessed promptly. Discontinue or modify once symptoms resolve.

Dietary Advice

While taking this formula, avoid greasy, fried, and fatty foods, as these generate Dampness and Heat that worsen the condition. Also avoid spicy, pungent foods (chili, garlic, pepper, alcohol) which aggravate intestinal inflammation. Cold and raw foods (salads, ice cream, cold drinks) should also be limited, as the formula is already very cold in nature, and adding cold food may further weaken digestive function. Favor bland, easily digestible foods such as plain rice porridge (congee), steamed vegetables, and simple broths. The classical dietary prohibition (shi ji) for dysentery formulas broadly recommends avoiding anything hard to digest, overly sweet, or irritating to the bowels.

Special Populations

Pregnancy

Contraindicated during pregnancy. The chief herb Bai Tou Weng (Pulsatilla root) is traditionally listed as unsuitable for pregnant women. Additionally, all four herbs in the formula are bitter and cold in nature, which can potentially harm the developing fetus and disturb the mother's digestive function. Huang Bai (Phellodendron bark) and Huang Lian (Coptis rhizome) are also generally cautioned against during pregnancy due to their strongly cold properties. Pregnant women experiencing dysentery-like symptoms should seek a practitioner who can select a safer alternative.

Breastfeeding

Caution is advised during breastfeeding. The formula's constituent herbs are strongly bitter and cold, and some components may pass into breast milk, potentially causing loose stools or digestive upset in the nursing infant. Huang Lian (Coptis) in particular contains berberine, which is known to transfer into breast milk in small amounts. While short-term use under practitioner supervision for acute dysentery may be considered if the clinical need is urgent, routine or prolonged use should be avoided. A breastfeeding mother should consult a qualified practitioner to weigh the risks and benefits, and to consider whether an alternative formula might be safer.

Pediatric Use

This formula can be used in children for acute Heat-type dysentery, but dosage must be significantly reduced based on the child's age and weight. A traditional guideline suggests children under 12 should receive approximately half the adult dose. For very young children (under 3), use should be conservative and closely supervised by a qualified practitioner. Because all four herbs are bitter and cold, the formula can easily upset a child's more delicate digestive system, so it should be used only for clearly diagnosed Heat-toxin patterns and discontinued promptly when symptoms resolve. Palatability may be an issue due to the intensely bitter taste. Decoctions can be sweetened very slightly or administered in small, frequent sips.

Drug Interactions

Huang Lian (Coptis rhizome) contains berberine, which has well-documented pharmacological interactions. Berberine can inhibit cytochrome P450 enzymes (particularly CYP3A4 and CYP2D6), potentially increasing blood levels of drugs metabolized through these pathways. Specific caution is warranted with:

  • Cyclosporine and other immunosuppressants: Berberine may increase their blood concentrations.
  • Hypoglycemic agents (metformin, sulfonylureas): Berberine itself lowers blood sugar, and combining it with diabetes medications could cause excessive blood sugar drops.
  • Anticoagulants and antiplatelet agents (warfarin, aspirin): The Blood-cooling and Blood-moving properties of the formula may theoretically enhance anticoagulant effects. Patients on blood thinners should be monitored.
  • Antibiotics (tetracyclines, macrolides): While concurrent use is common in Chinese clinical practice (often combined with sulfasalazine or mesalazine for ulcerative colitis), the additive antimicrobial effects should be monitored to avoid excessive disruption of gut flora.

Huang Bai (Phellodendron bark) also contains berberine and palmatine, contributing to the same interactions listed above.

Contraindications

Avoid

Spleen and Stomach Yang Deficiency. This formula is composed entirely of bitter, cold herbs that can readily injure Spleen Yang. It should never be used for diarrhea caused by Cold from Deficiency, where stools are watery without foul smell, and the person feels cold and fatigued.

Avoid

Diarrhea due to Cold from Deficiency (without Heat signs). If the diarrhea involves undigested food, cold limbs, and pale tongue, this formula will worsen the condition.

Avoid

Pregnancy. The formula contains Huang Bai (Phellodendron bark) and Huang Lian (Coptis rhizome), which are bitter-cold herbs traditionally cautioned against in pregnancy. Bai Tou Weng (Pulsatilla root) itself is also listed as not to be used during pregnancy.

Caution

Chronic, lingering dysentery with underlying Spleen Qi weakness. If a person has had diarrhea for a long time and shows signs of exhaustion and weakness, this formula alone is too harsh. The classical teaching is that for chronic dysentery, formulas like Wu Mei Wan are more appropriate.

Caution

Long-term use. Because all four herbs are bitter and cold, prolonged use can damage the digestive system. This formula is intended for acute, active Heat-type dysentery and should be discontinued once symptoms resolve.

Cautions & Warnings

Bai Tou Weng Tang is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Liu Wei Di Huang Wan.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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Treasure of the East

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