Xia Yu Xue Tang

Purge Stagnant Blood Decoction · 下瘀血湯

Also known as: Yu Xue Tang (瘀血汤), Xiayuxue Decoction

A potent classical formula with just three ingredients, designed to break up and expel hardened, old blood stasis lodged deep in the lower abdomen. Originally created for postpartum women whose abdominal pain did not respond to gentler treatments because of dried blood stuck below the navel, it is now also used for conditions like liver cirrhosis, ovarian cysts, and severe menstrual blockage where stubborn blood stasis is the root cause.

Origin Jin Gui Yao Lue (金匮要略), Chapter on Postpartum Diseases (妇人产后病脉证治) — Hàn dynasty, ~200 CE
Composition 3 herbs
Da Huang
King
Da Huang
Tao Ren
Deputy
Tao Ren
Tu Bie Chong
Deputy
Tu Bie Chong
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Xia Yu Xue Tang is designed to correct these specific patterns.

Why Xia Yu Xue Tang addresses this pattern

Xia Yu Xue Tang treats a severe form of Blood stasis known as dried blood (gan xue), where old, hardened blood has become fixed in the lower abdomen, often below the navel. This is more severe than ordinary Blood stagnation. The formula's three ingredients work in concert: Da Huang purges the stasis downward and clears associated heat, Tao Ren invigorates and mobilizes the congealed blood, and Tu Bie Chong breaks apart the deep, stubborn masses that have lodged in the network vessels. The original text specifically states that this formula is used when milder blood-moving formulas like Zhi Shi Shao Yao San have already failed, indicating the stasis has progressed to a fixed, hardened state requiring aggressive intervention.

A practitioner would look for one or more of these signs

Lower Abdominal Pain

Fixed, stabbing pain below the navel that worsens with pressure

Amenorrhea

Menstrual flow blocked or scanty due to blood stasis

Abdominal Masses

Palpable hard masses or fullness in the lower abdomen

Dark Menstrual Blood

Dark, clotted menstrual blood when present

Postpartum Abdominal Pain

Persistent postpartum abdominal pain unresponsive to milder treatment

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Xia Yu Xue Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, liver cirrhosis is understood as a condition where Blood stasis has become deeply entrenched in the Liver's network vessels over a long period. The Liver stores Blood and governs the smooth flow of Qi. When chronic pathogenic factors (such as dampness, heat, or toxins) damage the Liver over time, blood flow through its vessels becomes obstructed, and the stagnant blood gradually hardens and consolidates. This dried, fixed stasis then further impairs the Liver's ability to store and regulate Blood, creating a vicious cycle. The resulting obstruction also affects the Spleen's transport functions, potentially leading to fluid accumulation (ascites). Prominent signs include a dark or dull complexion, spider angiomas, pain in the flanks, an enlarged firm liver or spleen, and a dark purple tongue with stasis spots.

Why Xia Yu Xue Tang Helps

The renowned TCM physician Jiang Chunhua championed Xia Yu Xue Tang as the core formula for liver cirrhosis, using it as the base prescription with modifications according to individual patterns. Da Huang purges accumulated stasis from the Liver's vessels and clears heat-toxins that contribute to ongoing damage. Tu Bie Chong is particularly important here because its ability to penetrate hardened masses in the network vessels directly targets the fibrotic changes in the liver. Tao Ren mobilizes blood to support the expulsion process. Modern research has shown that Xia Yu Xue Tang can reduce liver fibrosis markers (alpha-SMA and collagen deposition) and improve liver enzyme levels, supporting the classical principle that removing stasis allows the body to regenerate healthy tissue.

Also commonly used for

Uterine Fibroids

Fixed abdominal masses with pain and menstrual disruption

Amenorrhea

Due to dried blood obstructing the channels

Endometriosis

Pelvic blood stasis with fixed pain

Deep Vein Thrombosis

Lower extremity blood stasis obstruction

Liver Fibrosis

Modern research supports anti-fibrotic mechanisms

Angina

Blood stasis in the chest vessels, combined with modifications

Amenorrhea

Severe menstrual pain from deep-seated stasis

What This Formula Does

Every TCM formula has a specific set of actions — here's what Xia Yu Xue Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Xia Yu Xue Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Xia Yu Xue Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Xia Yu Xue Tang works at the root level.

This formula addresses a condition where old, dried Blood (sometimes called "static" or "dead" Blood) has become lodged in the lower abdomen, specifically below the navel. In TCM theory, after childbirth the body expels lochia (postpartum discharge), but sometimes residual Blood fails to clear completely. Over time, this retained Blood dries out and becomes firmly fixed in the tissues, much like sediment becoming compacted.

This dried Blood obstructs the free flow of Qi and fresh Blood through the lower abdomen and uterus. Because the pathways are blocked, new Blood cannot circulate properly, leading to persistent abdominal pain that is fixed in location and does not respond to gentler treatments. The obstruction also disrupts menstruation, causing irregular periods or amenorrhea. The key distinguishing feature of this pattern is that the stasis is old, dried, and deeply entrenched. Unlike mild Blood stasis that responds to gentle activating herbs, this condition requires forceful "breaking" and purgative action to dislodge and expel the stubborn blockage downward and out of the body.

The formula works by combining powerful Blood-breaking substances with a strong purgative to physically clear the dried stasis through the bowels. The classical text describes that after taking the formula, the expelled material looks like pig liver, confirming that the old stagnant Blood has been successfully purged.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Cold

Taste Profile

Predominantly bitter with some sweet notes. The bitter flavor drives the formula's purgative and Blood-breaking action, directing stasis downward and out of the body.

Channels Entered

Liver Large Intestine Chong Mai (冲脉) Penetrating Vessel

Ingredients

3 herbs

The herbs that make up Xia Yu Xue Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
King — Main ingredient driving the formula
Da Huang

Da Huang

Rhubarb

Dosage 6 - 12g
Temperature Cold
Taste Bitter
Organ Affinity Spleen, Stomach, Large Intestine, Liver, Pericardium

Role in Xia Yu Xue Tang

The chief herb that purges downward to expel stagnant blood and clear heat from the blood level. Its bitter, cold nature drives accumulated dried blood (gan xue) out through the bowels, giving the pathogenic stasis a route of exit. Da Huang also cools the heat that has scorched blood into a dried, hardened state.
Deputies — Assists and enhances the King
Tao Ren

Tao Ren

Peach kernels

Dosage 6 - 9g
Temperature Neutral
Taste Bitter, Sweet
Organ Affinity Heart, Large Intestine, Liver

Role in Xia Yu Xue Tang

Strongly invigorates the Blood and breaks through stasis. Tao Ren enters the blood level to mobilize congealed blood, supporting Da Huang's purgative action by ensuring stagnant blood is dislodged before being expelled downward. Its mild moistening quality also helps lubricate the intestines to facilitate passage.
Tu Bie Chong

Tu Bie Chong

Ground Beetles

Dosage 6 - 9g
Temperature Cold
Taste Salty
Organ Affinity Liver
Preparation Legs removed; dry-fried (熬) before use

Role in Xia Yu Xue Tang

A potent Blood-breaking insect substance that penetrates into the network vessels to dislodge deep, stubborn, dried blood (gan xue) that ordinary herbs cannot reach. Tu Bie Chong softens hardness and disperses fixed masses, making it essential for treating old, consolidated stasis lodged below the navel. It also has analgesic properties that help relieve the pain caused by the stasis.

Why This Combination Works

How the herbs in Xia Yu Xue Tang complement each other

Overall strategy

This formula targets dried blood (gan xue) firmly lodged in the lower abdomen, a condition where stasis and heat have bound together so that ordinary blood-moving herbs are insufficient. The strategy is direct and forceful: break through the hardened stasis, dislodge it from the network vessels, and expel it downward through the bowels.

King herb

Da Huang (Rhubarb) serves as the King, using its bitter, cold, descending nature to purge accumulated stagnant blood while clearing the pathogenic heat that scorched the blood into a dried state. Its powerful downward-draining action provides the essential exit route for the expelled stasis. The Shen Nong Ben Cao Jing lists its primary action as "purging stagnant blood" (下瘀血), making it perfectly matched to this formula's purpose.

Deputy herbs

Tao Ren (Peach Kernel) and Tu Bie Chong (Ground Beetle) work as Deputies from complementary angles. Tao Ren is a premier blood-invigorating herb that mobilizes congealed blood and lubricates the passage for expulsion. Tu Bie Chong is an animal-based substance with exceptional ability to penetrate deep into the network vessels and break apart old, hardened stasis that plant-based herbs cannot adequately address. Together they ensure that both surface-level and deeply lodged dried blood is dislodged.

Notable synergies

Da Huang paired with Tao Ren is one of Zhang Zhongjing's signature combinations for Blood stasis, appearing across multiple formulas (Tao He Cheng Qi Tang, Da Huang Mu Dan Tang). Da Huang provides the purgative force while Tao Ren ensures the blood-level stasis is properly mobilized. The addition of Tu Bie Chong elevates this pairing specifically for dried blood conditions, as the insect's tunneling, dispersing nature reaches stasis that the plant pair alone cannot fully address. The honey used in the original pill preparation harmonizes the formula and moderates the harshness of the purgative action.

How to Prepare

Traditional preparation instructions for Xia Yu Xue Tang

Grind all three herbs into a fine powder. Mix with honey and form into 4 pills. Take one pill, dissolve it in approximately 200ml of rice wine (or yellow wine), and simmer gently until reduced to about 160ml. Strain and take the entire dose in a single serving on an empty stomach.

In modern clinical practice, the formula is more commonly prepared as a standard decoction: combine the herbs in 400ml of water, bring to a boil and simmer for 20-30 minutes until reduced to approximately 200ml. Divide into two doses and take twice daily. Wine may be added as a guide substance to enhance blood-invigorating action.

Common Modifications

How practitioners adapt Xia Yu Xue Tang for specific situations

Added
Dang Gui

9g, nourishes Blood and supports circulation

Dan Shen

9g, invigorates Blood and cools heat

Shu Di huang

9g, cools Blood and nourishes Yin

Dang Shen

9g, tonifies Qi to support the body during purgation

Chi Shao

9g, cools Blood and disperses stasis

Liver cirrhosis involves both Blood stasis and deficiency of Qi and Blood from chronic disease. Adding Qi and Blood tonics prevents the purgative herbs from further weakening the patient while reinforcing the blood-moving action.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Xia Yu Xue Tang should not be used or requires extra caution

Avoid

Pregnancy. This formula contains Da Huang and Zhe Chong, which are strongly Blood-breaking and can stimulate uterine contractions and cause miscarriage.

Avoid

Active hemorrhage or excessive bleeding conditions. The formula powerfully moves and breaks Blood, which could worsen uncontrolled bleeding.

Caution

Patients with significant Qi and Blood deficiency without concurrent Blood stasis. The formula is purely attacking in nature with no tonifying components, and could further deplete a weakened constitution.

Avoid

Menorrhagia (excessive menstrual bleeding) without confirmed Blood stasis. The purgative and Blood-breaking actions could dangerously increase blood loss.

Caution

Patients on anticoagulant or antiplatelet therapy. The strong Blood-moving herbs may potentiate bleeding risk.

Caution

Individuals with bleeding disorders or coagulation deficiencies.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Absolutely contraindicated during pregnancy. All three herbs in this formula pose serious risks to pregnancy. Da Huang (Rhubarb) is a strong purgative that stimulates intestinal and uterine contractions. Tao Ren (Peach Kernel) is a potent Blood-breaking herb traditionally listed among substances forbidden in pregnancy. Zhe Chong (Ground Beetle) is one of the strongest Blood-breaking animal substances in the materia medica, with known ability to disrupt pregnancy. The formula as a whole is designed to forcefully break and expel static Blood from the lower abdomen and uterus, which carries an extremely high risk of miscarriage, premature labor, or hemorrhage. There are no circumstances under which this formula should be used during pregnancy.

Breastfeeding

Use with caution during breastfeeding. Da Huang (Rhubarb) contains anthraquinone compounds (such as emodin and rhein) that can transfer into breast milk and may cause loose stools or diarrhea in the nursing infant. Zhe Chong (Ground Beetle) is a potent Blood-breaking animal substance whose components in breast milk are not well studied. While historically the formula was designed specifically for postpartum women (suggesting use during a period when breastfeeding may occur), its original indication was for short-term acute intervention immediately after delivery, not prolonged use. If used during breastfeeding, treatment should be kept as brief as possible, and the infant should be monitored for digestive disturbances. Consulting a qualified practitioner is essential.

Children

This formula is generally not appropriate for children. It was designed for a specific adult condition (postpartum Blood stasis) and contains powerfully Blood-breaking and purgative herbs. Zhe Chong (Ground Beetle) and Da Huang (Rhubarb) are too harsh for the immature digestive systems of children. There is no established pediatric dosing for this formula, and its clinical indications virtually never arise in pediatric practice. It should not be administered to children unless under the direct supervision of a highly experienced practitioner with a clear, confirmed indication.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Xia Yu Xue Tang

Anticoagulants and antiplatelet agents (e.g., warfarin, heparin, aspirin, clopidogrel): Da Huang and Tao Ren both have documented blood-activating and anticoagulant-like pharmacological effects. Combining this formula with anticoagulant or antiplatelet medications may significantly increase bleeding risk.

Cardiac glycosides (e.g., digoxin): Da Huang contains anthraquinone glycosides that can promote potassium loss through their purgative action on the bowels. Hypokalemia may potentiate digoxin toxicity.

Other laxatives or bowel-stimulating drugs: Concurrent use with pharmaceutical laxatives could cause excessive diarrhea, fluid loss, and electrolyte imbalance due to the additive purgative effect of Da Huang.

Iron supplements and oral medications with narrow therapeutic windows: The strong purgative action of this formula may reduce intestinal absorption of concurrently taken oral medications by accelerating transit time.

Usage Guidance

Practical advice for getting the most out of Xia Yu Xue Tang

Best time to take

On an empty stomach, as a single dose or as directed by the practitioner. The classical method was to take the full dose at once (顿服).

Typical duration

Acute, short-term use only: typically 1 to 3 doses. Classically given as a single large dose to purge the stasis, then reassessed.

Dietary advice

While taking this formula, avoid cold and raw foods, iced drinks, and greasy or heavy foods, as these can impede the circulation of Blood and counteract the formula's purpose. Because the formula is strongly purgative, easily digestible, warm foods such as congee, soups, and lightly cooked vegetables are preferred to support the digestive system. Avoid excessively spicy or hot foods that might aggravate any underlying Heat from Blood stasis. Alcohol in small amounts was part of the original preparation method, but large amounts of alcohol should be avoided during treatment.

Xia Yu Xue Tang originates from Jin Gui Yao Lue (金匮要略), Chapter on Postpartum Diseases (妇人产后病脉证治) Hàn dynasty, ~200 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Xia Yu Xue Tang and its clinical use

Jin Gui Yao Lue (《金匮要略》), 'Postpartum Diseases' chapter:

「产妇腹痛,法当以枳实芍药散,假令不愈者,此为腹中有瘀血著脐下,宜下瘀血汤主之;亦主经水不利。」

Translation: "When a postpartum woman has abdominal pain, the standard treatment is Zhi Shi Shao Yao San. If it does not bring about a cure, then there must be stagnant Blood lodged below the navel, and Xia Yu Xue Tang governs this condition. It also governs irregular menstruation."


Jin Gui Fang Ge Kuo (《金匮方歌括》) formula verse:

「脐中着痛瘀为殃,廿粒桃仁三两黄,更有䗪虫二十个,酒煎大下亦何伤。」

Translation: "When pain below the navel is caused by Blood stasis, use twenty peach kernels and three liang of rhubarb, plus twenty ground beetles. Decocted in wine and purged strongly downward, what harm can it do?"


Jin Gui Yao Lue (《金匮要略》), original preparation method:

「上三味末之,炼蜜和为四丸,以酒一升煮一丸,取八合,顿服之。新血下如豚肝。」

Translation: "Grind the three ingredients into powder, blend with refined honey to form four pills. Decoct one pill in one sheng of wine, reduce to eight ge, and take as a single dose. Fresh blood will be expelled resembling pig liver."

Historical Context

How Xia Yu Xue Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Xia Yu Xue Tang originates from Zhang Zhongjing's Jin Gui Yao Lue (Essential Prescriptions from the Golden Cabinet), written during the Eastern Han Dynasty (circa 200 CE). It appears in the chapter on postpartum diseases, where Zhang Zhongjing presents a systematic escalation of treatment for postpartum abdominal pain: first the milder Zhi Shi Shao Yao San for Qi stagnation, and then, if that fails, this more aggressive formula for deeply entrenched Blood stasis. This stepped approach reflects Zhongjing's characteristically precise clinical reasoning.

The formula is notable for its extreme simplicity: just three ingredients. This is unusual even among Zhongjing's prescriptions and reflects the urgency and directness of its purpose. The original preparation as honey pills decocted in wine is significant. Wine serves as both a vehicle that enhances blood circulation and a solvent that helps the herbs penetrate to where the stasis is lodged. The instruction to take the entire dose at once (顿服) indicates the formula was designed for acute, decisive intervention rather than gradual treatment. Classical commentators have categorized this formula among Zhang Zhongjing's most powerful "Blood-purging" prescriptions, placing it alongside Tao He Cheng Qi Tang and Di Dang Tang in a spectrum of increasing intensity for Blood stasis conditions.