Formula

Zhong Gan Ling

中感灵

Also known as:

Zhong Gan Ling Pian (中感灵片, Effective Cold and Flu Relief Tablets)

Properties

Heat-clearing formulas · Cold

Key Ingredients

Mao Dong Qing, Ge Gen

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Select Product Type

Select Supplier

Select Size

Quantity

$0.00 ($0.00/g)
Made to order · Non-cancellable once ordered · Policy
For shipments to: United States Change
Standard Shipping (3-5 business days): $4.99
Express Shipping (1-2 business days): $9.99
Free shipping on orders over $75

About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A modern Chinese herbal formula designed for severe colds and influenza with strong Heat signs such as high fever, intense sore throat, body aches, and headache. It works by powerfully clearing Heat and toxins, dispelling Wind, cooling the Blood, and moistening the throat. It is most appropriate when a cold or flu has progressed beyond the early stage and significant Heat has built up in the body.

Formula Category

Main Actions

  • Clears Heat
  • Drains Fire
  • Disperses Wind-Heat
  • Cools the Blood
  • Resolves Toxicity
  • Releases the Muscle Layer
  • Benefits the Throat

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Zhong Gan Ling is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Zhong Gan Ling addresses this pattern

Zhong Gan Ling is specifically formulated for severe Wind-Heat invasion where the pathogenic Heat has intensified significantly. The formula's combination of powerful Heat-clearing herbs (Shi Gao, Ban Lan Gen, Mao Dong Qing) with exterior-releasing herbs (Ge Gen, Qiang Huo) makes it ideal for Wind-Heat that has progressed beyond the initial stage. Unlike milder Wind-Heat formulas such as Yin Qiao San, Zhong Gan Ling brings much heavier Heat-clearing power to bear, addressing situations where the Heat is blazing rather than merely warm.

A practitioner would look for one or more of these signs

Fever

High fever, feeling hot, preference for cold

Sore Throat

Severe sore throat, red and swollen

Headaches

Intense headache

Body Aches

Generalized body aches and joint pain

Back Stiffness

Stiff, tight neck and shoulders

Thirst

Strong thirst with desire for cold drinks

How It Addresses the Root Cause

Zhong Gan Ling addresses a specific and urgent situation: an external pathogenic invasion (typically Wind-Heat or epidemic toxin) that has broken through the body's surface defenses and is generating intense internal Heat. In TCM terms, the pathogen has moved past the initial Tai Yang (Greater Yang) or Wei (Defensive) stage and is penetrating into the Qi level or the Yang Ming (Yang Brightness) stage.

When the body's defensive Qi fails to fully expel a Wind-Heat invasion at the surface, the trapped pathogen transforms into blazing Heat that lodges deeper in the body. This generates strong Heat signs: high fever, a flushed red face, intense thirst, sore and swollen throat, restlessness, and a forceful rapid pulse. The Heat also begins to damage the body's Yin fluids and can enter the Blood level, causing further complications. This is why the pattern often includes dry throat, irritability, and sometimes signs of Blood Heat. The neck and shoulder stiffness reflect the residual exterior component that has not fully resolved even as the pathogen drives inward.

The formula intervenes at this critical juncture by simultaneously clearing the intense interior Heat (through cold and bitter herbs that drain Fire), expelling any remaining exterior pathogen (through herbs that release the muscle layer), cooling and protecting the Blood from Heat damage, and resolving toxic Heat that threatens the throat and upper body. The strategy is aggressive and short-term, matching the urgent nature of an acute febrile illness that is rapidly intensifying.

Formula Properties

Temperature

Cold

Taste Profile

Predominantly bitter and acrid (pungent), with some sweet notes. Bitter to clear Heat and drain Fire, acrid to dispel Wind and release the exterior, sweet to protect fluids.

Target Organs
Lungs Stomach Liver
Channels Entered
Lung Stomach Liver Bladder

Formula Origin

Modern formula, early 20th century, Meizhou Pharmaceutical Manufactory (梅州制药厂), Guangdong, China

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Zhong Gan Ling

Detailed information about each herb in Zhong Gan Ling and their roles

Ma
Mao Dong Qing

Pubescent holly root

Dosage: 15 - 30g

Temperature Cold
Taste Bitter (苦 kǔ), Astringent (涩 sè)
Organ Affinity Heart, Lungs, Liver, Large Intestine
Parts Used Root (根 gēn)
Role in Zhong Gan Ling

The primary Heat-clearing herb in the formula. Mao Dong Qing clears toxic Heat, invigorates Blood circulation, and unblocks the channels. It powerfully resolves Heat toxins at the Qi level and supports the body's circulation to prevent Blood stasis caused by intense Heat.

Ge Gen
Ge Gen

Kudzu root

Dosage: 12 - 30g

Temperature Cool
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Root (根 gēn)
Role in Zhong Gan Ling

Releases the exterior and relaxes the muscles, particularly relieving tightness and stiffness in the neck and upper back. It also clears Heat, generates fluids to address thirst, and raises the clear Yang. Together with Mao Dong Qing, these two King herbs comprise about half the formula by weight.

Ban Lan Gen
Ban Lan Gen

Isatis root

Dosage: 9 - 30g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Stomach
Parts Used Root (根 gēn)
Role in Zhong Gan Ling

Drains Heat, resolves Fire toxins, cools the Blood, and strongly benefits the throat. Ban Lan Gen has potent antiviral and antibacterial actions and is essential for treating the severe sore throat and toxic Heat that characterize epidemic febrile diseases.

Shi Gao
Shi Gao

Gypsum

Dosage: 15 - 30g

Temperature Cold
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Lungs, Stomach
Parts Used Mineral (矿物 kuàng wù)
Role in Zhong Gan Ling

Clears Heat and drains Fire from the Qi level and Yang Ming channel. Shi Gao is the premier mineral for reducing high fever and resolving intense internal Heat. It also clears Lung and Stomach Heat and generates fluids.

Ma Bian Cao
Ma Bian Cao

Vervain

Dosage: 9 - 15g

Temperature Cool
Taste Bitter (苦 kǔ)
Organ Affinity Liver, Spleen
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Zhong Gan Ling

Clears Heat, invigorates and cools the Blood, dispels Blood stasis, and promotes urination. Ma Bian Cao supports the formula's Blood-cooling actions and helps channel Heat downward and out through urination, providing an exit route for pathogenic Heat.

Qing Hao
Qing Hao

Sweet wormwood

Dosage: 6 - 12g

Temperature Cold
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Kidneys
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Zhong Gan Ling

Clears deficiency-level Heat and Heat from the Yin level without injuring Qi, Blood, or Yin. Qing Hao addresses residual or deep-lying Heat, cools the Blood, and helps prevent the pathogenic Heat from damaging the body's Yin fluids as the disease progresses inward.

Qiang Huo
Qiang Huo

Notopterygium root and rhizome

Dosage: 3 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Urinary Bladder, Kidneys
Parts Used Rhizome (根茎 gēn jīng)
Role in Zhong Gan Ling

Releases the exterior, dispels Wind-Cold, relieves pain in the upper body and joints, and guides the formula's actions to the Tai Yang channel and Governing Vessel. Qiang Huo directs the other herbs to the head, neck, and upper back where pain from external invasion concentrates.

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

Loading storage and consumption information...

Best Time to Take

Every 4 hours during acute episodes, or 2-3 times daily for moderate symptoms. Can be taken regardless of meals, though taking with a small amount of warm water on a relatively empty stomach may enhance absorption.

Typical Duration

Acute use only: 1-5 days. Discontinue as soon as fever breaks and Heat signs resolve.

Dietary Advice

While taking Zhong Gan Ling, avoid greasy, fried, and rich foods that generate internal Heat and Dampness, as these impede the formula's Heat-clearing action. Avoid spicy, warming foods (lamb, chili, ginger, cinnamon, alcohol) that add more Heat to an already overheated body. Favor light, easily digestible foods: plain rice congee, clear vegetable soups, mung bean soup, pears, watermelon, and cooling teas (chrysanthemum, mint). Stay well hydrated, as the intense Heat of the illness depletes body fluids. Avoid dairy and cold raw foods that are difficult to digest when the Spleen is under stress from acute illness.

Special Populations

Pregnancy

Contraindicated during pregnancy. The formula contains Ma Bian Cao (Verbena/Vervain), which has traditionally recognized Blood-invigorating and Blood-dispersing properties that may stimulate uterine activity. Mao Dong Qing (Pubescent Holly Root) also invigorates Blood. Additionally, the overall strongly cold nature of the formula poses risks to fetal development. Women who are pregnant or suspect pregnancy should not take this formula.

Breastfeeding

Not recommended during breastfeeding without professional guidance. Several herbs in this formula (Ma Bian Cao, Mao Dong Qing) have Blood-invigorating properties, and the strongly cold nature of the formula may potentially affect the nursing infant through breast milk, possibly causing digestive upset (loose stools) in the baby. Ban Lan Gen (Isatis Root) in high or prolonged doses has been associated with gastrointestinal side effects. If a breastfeeding mother has an acute febrile illness requiring treatment, a qualified practitioner should assess whether the short-term benefits outweigh potential risks.

Pediatric Use

Zhong Gan Ling may be used in children for acute febrile conditions, but dosage must be significantly reduced and use should be supervised by a qualified practitioner. General pediatric dosage guidelines suggest roughly half the adult dose for children aged 6-12, and one-quarter for children aged 2-6. Children under 2 should generally not take this formula without direct practitioner supervision. Because the formula is strongly cooling, children (whose digestive systems are relatively delicate) are more susceptible to side effects like loose stools or reduced appetite. The formula should be discontinued promptly once acute Heat signs resolve. Tablet forms may need to be crushed and mixed with a small amount of warm water for younger children.

Drug Interactions

Anticoagulant and antiplatelet medications (warfarin, heparin, aspirin, clopidogrel): Several herbs in this formula have Blood-invigorating properties. Mao Dong Qing (Pubescent Holly Root) and Ma Bian Cao (Vervain) both activate Blood circulation and disperse stasis. Ge Gen (Kudzu Root) contains puerarin and other isoflavones that have demonstrated effects on blood viscosity, thrombosis, and platelet function in animal studies. Concurrent use with anticoagulant or antiplatelet drugs may theoretically increase bleeding risk. Puerarin has also been shown in animal studies to affect warfarin pharmacokinetics by inducing certain cytochrome P450 enzymes. Patients on blood-thinning medications should consult their physician before using this formula.

Antihypertensive medications: Mao Dong Qing has cardiovascular effects including vasodilation. Combined use with antihypertensive drugs could theoretically potentiate blood-pressure-lowering effects. Monitoring is advised.

Immunosuppressant drugs: The formula's immune-activating properties (through its Heat-clearing and toxin-resolving herbs) may theoretically counteract immunosuppressive therapy. Patients on immunosuppressants should avoid this formula without medical supervision.

Contraindications

Avoid

Pregnancy. This formula contains Blood-moving and strongly cold herbs (Ma Bian Cao/Vervain, Mao Dong Qing/Pubescent Holly Root) that may pose risks during pregnancy.

Avoid

Wind-Cold patterns. This formula is designed for Wind-Heat and interior Heat conditions. Using it when strong chills dominate without Heat signs will worsen the condition by further cooling an already cold pattern.

Caution

Spleen and Stomach deficiency with cold. The heavily cold nature of this formula can injure the digestive system in people with constitutional coldness, causing loose stools or diarrhea. If loose stools develop, the dosage should be reduced or the formula discontinued.

Caution

Hemorrhagic disorders or concurrent anticoagulant/antiplatelet therapy. Several herbs in this formula (Mao Dong Qing, Ma Bian Cao) invigorate Blood and may increase bleeding risk.

Caution

Prolonged use beyond the acute phase. This is a strongly cooling, Heat-clearing formula meant for short-term acute use. Extended use can damage the Spleen Yang and deplete Qi.

Cautions & Warnings

is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Liu Wei Di Huang Wan.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

Quantity Description

Loading quantity information...

Concentration Ratio

Loading concentration information...

Fabrication Method

Loading fabrication information...

Supplier Certifications

Loading certifications information...

Supplier Information

Treasure of the East

Loading supplier information...

Loading supplier attributes...

Miscellaneous Info

No additional information available