Formula

Da Cheng Qi Tang

Major Rhubarb Combination | 大承气汤

Also known as:

Major Rhubarb Decoction

Properties

Cold-purging formulas · Cold

Key Ingredients

Da Huang

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A powerful classical formula used to urgently clear severe Heat and blockage from the intestines. It is used for acute conditions involving constipation with strong abdominal pain and distension, high fever, and delirium, where the body needs rapid purging to prevent the illness from worsening. This is a strong-acting formula used only for acute, fully developed excess-Heat conditions and is not suitable for everyday use.

Formula Category

Main Actions

  • Vigorously Purges Heat Accumulation
  • Promotes Bowel Movement
  • Moves Qi and Relieves Distension
  • Softens Hardness and Moistens Dryness
  • Clears interior Heat from the Yangming

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Da Cheng Qi Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Da Cheng Qi Tang addresses this pattern

Yang Ming Organ Heat (also called Yang Ming Fu Shi, 阳明腑实证) is the primary pattern this formula treats. It develops when pathogenic Heat penetrates deeply into the Stomach and Intestines, combining with waste matter to form a dry, solid blockage. The Heat scorches the body's fluids, drying out the stool, while the blockage prevents the normal downward movement of Qi. Da Huang and Mang Xiao directly purge this Heat-bound accumulation, while Hou Po and Zhi Shi restore the flow of Qi. Classical sources describe this as the condition where all four cardinal signs are present: distension (痞, pǐ), fullness (满, mǎn), dryness (燥, zào), and solidity (实, shí).

A practitioner would look for one or more of these signs

Constipation

Complete inability to pass stool, with frequent passage of gas (转矢气)

Abdominal Pain

Severe abdominal pain that worsens with pressure, abdomen feels hard to the touch

Abdominal Distention

Pronounced bloating and fullness of the entire abdomen

Afternoon Fever

Tidal fever peaking in the late afternoon (3-5 PM), the Yang Ming time

Delirium

Delirious speech or incoherent muttering due to Heat disturbing the mind

Excessive Sweating

Profuse sweating on the palms and soles (手足濈然汗出)

How It Addresses the Root Cause

Da Cheng Qi Tang addresses a condition where intense Heat has lodged deep in the Stomach and Intestines — what TCM calls Yangming Fu (organ) Excess (阳明腑实证). This typically develops when a pathogen that initially attacked the body's surface transforms into Heat as it moves inward, or when internal Heat accumulates and dries out the intestinal contents.

The Heat bakes the fluids in the intestines, causing stool to become dry and hard ('dry stool', 燥屎). This creates a vicious cycle: the hardened mass blocks the downward flow of Qi through the digestive tract, which generates further stagnation and more Heat. The result is the four hallmark signs known as pǐ, mǎn, zào, shí (痞满燥实) — a sense of hard blockage below the chest (pǐ), abdominal distention and fullness (mǎn), dry hardened stool (zào), and firm, painful swelling that resists pressure (shí). As the Heat blazes upward it disturbs the mind, causing delirium and agitated speech. The body attempts to vent Heat through the hands and feet, producing profuse sweating on the extremities, and fever characteristically peaks in the late afternoon ('tidal fever').

In severe cases, the Heat can cause paradoxical conditions: 'heat-bypass diarrhea' (热结旁流), where watery fluid is forced around the solid blockage and leaks out as foul-smelling liquid stool, even though the core problem is obstruction; 'heat reversal' (热厥), where Qi is so trapped internally that the limbs become cold despite raging interior Heat; or convulsions and mania from Heat scorching the sinews or disturbing the spirit. In all cases, the underlying logic is the same: the priority is to 'urgently purge to preserve Yin' (急下存阴) — forcefully expelling the bound Heat to rescue the body's rapidly depleting fluids before they are consumed entirely.

Formula Properties

Temperature

Cold

Taste Profile

Predominantly bitter and salty — bitter to drain Heat downward and move stagnation, salty to soften hardness and draw fluid into the intestines to moisten dry stool.

Target Organs
Stomach Large Intestine Spleen
Channels Entered
Stomach Large Intestine Spleen

Formula Origin

Shang Han Lun (傷寒論) by Zhang Zhongjing

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Da Cheng Qi Tang

Detailed information about each herb in Da Cheng Qi Tang and their roles

Kings
Deputies
Assistants
Da Huang
Da Huang

Rhubarb root and rhizome

Dosage: 9 - 12g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Spleen, Stomach, Large Intestine, Liver, Pericardium
Parts Used Root (根 gēn)
Role in Da Cheng Qi Tang

The primary purgative herb. Da Huang drains Heat and unblocks the bowels, flushing accumulated Heat and stagnant waste from the Stomach and Intestines. Its bitter, cold nature directly addresses the excess Heat at the root of the condition.

Mang Xiao
Mang Xiao

Mirabilite (Glauber's salt)

Dosage: 9 - 12g

Temperature Cold
Taste Bitter (苦 kǔ), Salty (咸 xián)
Organ Affinity Stomach, Large Intestine
Parts Used Mineral (矿物 kuàng wù)
Role in Da Cheng Qi Tang

Assists Da Huang in purging Heat and unblocking the bowels. Its salty, cold nature softens hardened stool and moistens dryness, directly addressing the dry, compacted fecal masses that are a hallmark of this condition. Together with Da Huang, their combined purgative power is greatly strengthened.

Hou Po
Hou Po

Magnolia bark

Dosage: 12 - 15g

Temperature Warm
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs, Large Intestine
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Da Cheng Qi Tang

Moves Qi and relieves abdominal fullness and distension. The accumulated waste causes severe Qi stagnation, and Hou Po's aromatic, bitter-warm nature powerfully disperses this bloating and congestion. It also helps propel the waste downward, assisting the purgative action of Da Huang and Mang Xiao.

Zhi Shi
Zhi Shi

Immature bitter orange

Dosage: 9 - 12g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn), Sour (酸 suān)
Organ Affinity Spleen, Stomach, Large Intestine
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Da Cheng Qi Tang

Breaks up Qi stagnation and reduces focal distension and a sensation of hardness under the heart (epigastric area). Works in tandem with Hou Po to restore the downward movement of Qi in the digestive tract, accelerating the expulsion of the Heat-bound accumulation.

Modern Research (4 studies)

  • Systematic Review and Meta-Analysis: Da-Cheng-Qi Decoction for Intestinal Obstruction (2014)
  • Pilot RCT: Modified Da-Cheng-Qi Decoction Reduces Intra-abdominal Hypertension in Severe Acute Pancreatitis (2012)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

As needed for the acute condition, not tied to mealtimes. Traditionally divided into two warm doses. Take the first dose and observe; if bowels move, do not take the second dose.

Typical Duration

Acute use only: typically 1-3 doses. Stop immediately once bowels move (得下余勿服). Never used as ongoing treatment.

Dietary Advice

During treatment, avoid foods that are hard to digest, greasy, fried, spicy, or excessively rich, as these generate Heat and burden the already overloaded digestive system. Cold and raw foods should also be avoided, not because they conflict with the formula's cold nature, but because they are difficult to digest when gut function is compromised. After successful purging, it is important to resume eating very gradually. Start with thin rice porridge (congee) and other bland, easily absorbed foods. Do not immediately eat heavy meals — the digestive system has just been forcefully cleared and needs gentle rebuilding. Classical texts emphasize that the recovery diet after purging should nurture the Stomach Qi without overwhelming it. Drink adequate warm fluids to replenish the fluids lost through purging.

Special Populations

Pregnancy

Contraindicated. Da Huang (Rhubarb) contains anthraquinone compounds that stimulate intestinal peristalsis and can also provoke uterine contractions. Mang Xiao (Glauber's salt, sodium sulfate) is an osmotic purgative that causes significant fluid shifts. Together they produce a powerfully cathartic effect that can endanger the pregnancy. The classical texts explicitly list this formula among those forbidden during pregnancy (孕妇禁用). Hou Po (Magnolia bark) may also contribute to uterine stimulation. This formula must not be used at any stage of pregnancy.

Breastfeeding

Use with caution. Da Huang (Rhubarb) anthraquinone metabolites are known to pass into breast milk and may cause loose stools or diarrhea in the nursing infant. Mang Xiao can alter electrolyte balance. If this formula is clinically necessary during breastfeeding, it should be used for the shortest duration possible (typically 1-2 doses), and the infant should be monitored for digestive disturbance. Temporary suspension of breastfeeding during treatment and for 24 hours after the last dose may be advisable. Consult a qualified practitioner.

Pediatric Use

Da Cheng Qi Tang is a powerful purgative formula and should be used with extreme caution in children. Pediatric use is generally reserved for genuine acute Yangming excess patterns (high fever, abdominal distension, confirmed constipation with hard stool) and should only be administered under close supervision by an experienced practitioner. Dosage must be significantly reduced according to age and body weight — typically one-third to one-half of the adult dose for school-age children, and even less for younger children. Infants and toddlers should generally not receive this formula. The classical instruction 'stop when the bowels move' (得下余勿服) is especially critical in children, as their Qi and fluids are easily depleted. Electrolyte imbalance from the purgative action of Mang Xiao is a particular concern in small children. Monitor closely for dehydration.

Drug Interactions

Anticoagulants and antiplatelet drugs (e.g. warfarin, heparin, aspirin, clopidogrel): Da Huang (Rhubarb) has demonstrated effects on blood clotting time and contains compounds that can potentiate anticoagulant activity. Concurrent use may increase bleeding risk.

Cardiac glycosides (e.g. digoxin): The strong purgative action of the formula, particularly from Mang Xiao (sodium sulfate), can cause significant potassium loss through diarrhea. Hypokalemia increases sensitivity to cardiac glycosides and raises the risk of digitalis toxicity.

Diuretics (especially potassium-depleting types like furosemide, hydrochlorothiazide): Combined use with this intensely purgative formula may lead to dangerous electrolyte depletion, particularly potassium and sodium.

Oral medications with narrow therapeutic windows: The rapid intestinal transit caused by Da Cheng Qi Tang may reduce the absorption time and bioavailability of concurrently administered oral drugs, including oral contraceptives, anti-epileptics, and immunosuppressants.

Corticosteroids: These already promote potassium loss; combining them with a formula that causes significant bowel purging may compound electrolyte imbalance.

Contraindications

Avoid

Pregnancy. Da Huang (Rhubarb) and Mang Xiao (Glauber's salt) are strongly purgative and can stimulate uterine contractions, posing serious risk to the pregnancy.

Avoid

Exterior (surface-level) pathogen still unresolved. If the person still has chills, fever, and body aches indicating the pathogen is at the body's surface, purging the interior will draw the pathogen deeper and worsen the condition.

Avoid

Spleen and Stomach deficiency cold (cold-type digestive weakness). This formula is intensely cold and purgative, which would severely damage an already weak and cold digestive system.

Avoid

Kidney Yang deficiency. The cold, draining nature of this formula will further deplete the body's warming function.

Avoid

Suspected intestinal perforation or peritonitis. While the symptoms may superficially resemble Yangming excess, purging in these surgical emergencies can be life-threatening.

Caution

Elderly, frail, or constitutionally weak patients. The formula's powerful purgative action can easily damage Qi and Yin in those without robust constitution. If purging is necessary, the dose should be significantly reduced and the patient closely monitored.

Caution

Tidal fever (afternoon fever) present but stool is not yet hard or dry. Zhang Zhongjing specifically warns: if stools have not fully hardened, premature purging will cause diarrhea and harm the patient.

Caution

Yin or fluid deficiency with mild constipation. If dryness is from fluid depletion rather than Heat excess, gentle moistening formulas are preferred over forceful purging.

Caution

Patients with frequent vomiting. The Shang Han Lun notes that even with Yangming signs, if vomiting is prominent, this formula should not be used, as the upward counterflow of Stomach Qi makes purging inappropriate.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

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Granules

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Treasure of the East

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