Formula

Bai Zi Yang Xin Wan

Arborvitae Seed Nourishing Pill | 柏子养心汤

Also known as:

Bo Zi Yang Xin Wan , Bai Zi Yang Xin Wan , Yang Xin Tang , Yang Xin Wan , Astragalus and Zizyphus

Properties

Heart-nourishing and spirit-calming formulas · Slightly Warm

Key Ingredients

Huang Qi, Dang Shen, Dang Gui

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula used to nourish the Heart and calm the mind in people experiencing poor sleep, palpitations, anxiety, forgetfulness, and night sweats caused by depletion of Blood and Yin. It works by rebuilding the body's deep reserves of Blood and nourishing fluids in the Heart, Liver, and Kidneys, providing the spirit with a stable foundation for restful sleep and emotional balance. Particularly well suited for older adults, postpartum recovery, or anyone with a long-standing pattern of deficiency.

Formula Category

Main Actions

  • Nourishes Heart Blood
  • Tonifies Heart Qi
  • Nourishes Yin
  • Calms the Spirit
  • Moistens the Intestines and Unblocks the Bowels

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Bai Zi Yang Xin Wan is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Bai Zi Yang Xin Wan addresses this pattern

Bai Zi Yang Xin Wan directly targets Heart Qi deficiency, the core pattern this formula was designed to address. When Heart Qi is insufficient, the Heart loses its ability to govern Blood and house the Shen (spirit/mind), leading to palpitations, a tendency to be easily startled, and mental restlessness.

The formula uses Dang Shen (Codonopsis) and honey-prepared Huang Qi (Astragalus) as major Qi tonics to rebuild Heart and Spleen Qi. Bai Zi Ren (Arborvitae seed) and Suan Zao Ren (Sour jujube seed) directly nourish the Heart and calm the spirit. Yuan Zhi (Polygala) opens the Heart orifices and settles anxiety. Rou Gui (Cinnamon bark) provides gentle warmth to support Heart Yang, which is often weakened alongside Heart Qi. Wu Wei Zi (Schisandra) astringes leaking Qi and prevents further loss through sweating. Together, these herbs restore the Heart's capacity to house the Shen and maintain stable heart rhythm.

A practitioner would look for one or more of these signs

Palpitations

Especially upon exertion or when startled

Shortness Of Breath

Worsened by physical activity

Eye Fatigue

General tiredness and lack of vitality

Spontaneous Sweat

Sweating without exertion, indicating Qi failing to secure the exterior

Dull Pale Complexion

Reflecting insufficient Qi and Blood to nourish the face

How It Addresses the Root Cause

This formula addresses a condition in which the Heart has become depleted in both Qi and Blood, leaving the spirit (Shen) without a stable home. In TCM, the Heart is the residence of the Shen, the aspect of consciousness responsible for awareness, sleep, emotional balance, and memory. When the Heart's Blood and Qi are sufficient, the Shen is anchored and calm. When they become depleted through chronic illness, prolonged emotional strain, overwork, or the natural decline of aging, the Shen becomes restless and unsettled.

The core pathomechanism is a deficiency pattern involving both Qi weakness and Blood/Yin insufficiency in the Heart, often extending to the Liver and Kidneys. The Heart requires Blood to house the Shen; without it, sleep becomes disturbed by vivid dreams, palpitations arise without physical exertion, and the person becomes easily startled or anxious. Qi deficiency contributes fatigue, shortness of breath, and spontaneous or night sweating, as weakened Qi cannot properly hold fluids within the body. When Blood and Yin are both depleted, dryness follows: the intestines lose moisture (causing constipation), the mouth and throat become dry, and low-grade internal heat from Yin deficiency may produce night sweats and restlessness.

In more severe or long-standing cases, the Kidneys and Liver are also affected. The Kidneys store Essence (Jing) that produces Marrow, which supports brain function and memory. The Liver stores Blood and governs the smooth flow of emotions. When all three organs are deficient in Blood and Yin, the result is a person who feels exhausted yet cannot rest, whose mind wanders yet cannot concentrate, and whose spirit is agitated yet lacks the vitality to cope.

Formula Properties

Temperature

Slightly Warm

Taste Profile

Predominantly sweet and slightly bitter, with mild pungent warmth. The sweetness tonifies Qi and Blood, the bitterness settles and calms the Heart Spirit, and the slight pungency gently moves Blood.

Target Organs
Heart Liver Kidneys
Channels Entered
Heart Kidney Spleen Liver

Formula Origin

Ye Tian Shi Gynecology (16th century)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Bai Zi Yang Xin Wan

Detailed information about each herb in Bai Zi Yang Xin Wan and their roles

Kings
Deputies
Assistants
Envoys
Huang Qi
Huang Qi

Astragalus root

Dosage: 9 - 15g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs
Parts Used Root (根 gēn)
Role in Bai Zi Yang Xin Wan

Honey-prepared Astragalus is the principal Qi tonic in this formula. Its sweet, warm nature powerfully supplements Qi and promotes the generation of Blood, directly addressing the core deficiency of Heart Qi that underlies the pattern.

Dang Shen
Dang Shen

Codonopsis root

Dosage: 6 - 9g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs
Parts Used Root (根 gēn)
Role in Bai Zi Yang Xin Wan

Codonopsis supplements the middle Qi and nourishes Blood. Working alongside Huang Qi, it strengthens the Spleen and Heart to generate Qi and Blood, forming the core tonifying strategy of the formula.

Dang Gui
Dang Gui

Chinese Angelica root

Dosage: 6 - 12g

Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen
Parts Used Root (根 gēn)
Role in Bai Zi Yang Xin Wan

Angelica root tonifies and invigorates the Blood. Its warm, sweet nature nourishes Heart Blood while gently promoting circulation, preventing Blood stasis from the formula's heavy supplementation.

Bai Zi Ren
Bai Zi Ren

Arborvitae seed

Dosage: 6 - 9g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Kidneys, Large Intestine
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Bai Zi Yang Xin Wan

Biota seed nourishes the Heart and calms the spirit. Its oily, sweet nature enriches Heart Blood and settles restlessness, directly addressing palpitations, insomnia, and dream-disturbed sleep.

Suan Zao Ren
Suan Zao Ren

Sour jujube seed

Dosage: 6 - 9g

Temperature Neutral
Taste Sweet (甘 gān), Sour (酸 suān)
Organ Affinity Heart, Liver, Gallbladder
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Bai Zi Yang Xin Wan

Sour Jujube seed nourishes Heart and Liver Blood and calms the spirit. Its sour-sweet nature astringes Qi and fluids, helping to contain night sweats and ease insomnia.

Yuan Zhi
Yuan Zhi

Polygala root

Dosage: 3 - 6g

Temperature Warm
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Heart, Kidneys, Lungs
Parts Used Root (根 gēn)
Role in Bai Zi Yang Xin Wan

Prepared Polygala calms the spirit, opens the Heart orifices, and facilitates communication between the Heart and Kidneys. It helps address forgetfulness and restless sleep due to Qi deficiency.

Wu Wei Zi
Wu Wei Zi

Schisandra berry

Dosage: 3 - 6g

Temperature Warm
Taste Sour (酸 suān), Sweet (甘 gān)
Organ Affinity Lungs, Heart, Kidneys
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Bai Zi Yang Xin Wan

Vinegar-prepared Schisandra berry astringes Qi and generates fluids. Its sour taste contains leaking Heart Qi, prevents sweating, and calms the spirit, strengthening the formula's ability to consolidate deficient Qi.

Fu Ling
Fu Ling

Poria

Dosage: 9 - 15g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Bai Zi Yang Xin Wan

Poria strengthens the Spleen, promotes healthy fluid metabolism, and calms the spirit. It supports the digestive system to ensure proper generation of Qi and Blood, while contributing gentle calming effects.

Zhu Sha
Zhu Sha

Cinnabar

Dosage: 0.3 - 1g

Temperature Cool
Taste Sweet (甘 gān)
Organ Affinity Heart
Parts Used Mineral (矿物 kuàng wù)
Role in Bai Zi Yang Xin Wan

Cinnabar is heavy and settling, used to sedate the Heart and calm the spirit. It clears Heat from the Heart and anchors restless spirit, providing immediate relief from palpitations and anxiety.

Rou Gui
Rou Gui

Cinnamon bark

Dosage: 1 - 3g

Temperature Hot
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Heart, Liver, Spleen, Kidneys
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Bai Zi Yang Xin Wan

Cinnamon bark warms the interior and disperses cold, assisting Yang and warming the channels. In this formula targeting Heart Qi deficiency with cold, it helps restore warmth to the Heart and promotes the generation and circulation of Qi and Blood.

Chuan Xiong
Chuan Xiong

Szechuan lovage rhizome

Dosage: 3 - 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium
Parts Used Rhizome (根茎 gēn jīng)
Role in Bai Zi Yang Xin Wan

Ligusticum invigorates Blood and moves Qi. As an assistant, it ensures the Blood-tonifying herbs do not cause stagnation, keeping the circulation flowing smoothly and guiding the formula's nourishing effects throughout the body.

Ban Xia
Ban Xia

Pinellia tuber

Dosage: 6 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Bai Zi Yang Xin Wan

Pinellia fermented mass dries dampness, transforms phlegm, and aids digestion. It protects the Spleen and Stomach from the heavy, rich tonifying herbs in the formula, ensuring they can be properly absorbed without causing bloating or dampness.

Gan Cao
Gan Cao

Licorice root

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Bai Zi Yang Xin Wan

Honey-prepared licorice supplements Qi, benefits the Heart, and harmonizes all the herbs in the formula. It moderates harsh properties, guides the actions of the other ingredients, and contributes its own Heart-nourishing effect.

Modern Research (1 study)

  • Health risk assessment for human mercury exposure from Cinnabaris-containing Baizi Yangxin Pills in healthy volunteers (Pharmacokinetic study, 2024)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

After meals, twice daily (morning and evening). An extra dose may be taken 30 minutes before bedtime if insomnia is the primary concern.

Typical Duration

Typically taken for 2 to 4 weeks as an initial course, with reassessment by a practitioner. Due to cinnabar content in the modern version, continuous use beyond 4 to 6 weeks is not recommended without medical supervision.

Dietary Advice

Avoid stimulating beverages such as strong tea, coffee, and alcohol, especially before bedtime, as they can counteract the calming effect of the formula. Spicy, greasy, and heavily fried foods should be minimized, as they can generate internal Heat or obstruct digestion, working against the formula's gentle tonifying action. Favor easily digestible, nourishing foods such as congee, jujube dates, lotus seeds, longan fruit, and lightly cooked vegetables. Warm, cooked meals are preferred over cold and raw foods to support the Spleen's digestive function and help the formula work effectively.

Modern Usage

Bai Zi Yang Xin Wan is for symptoms such as insomnia, palpitations, shortness of breath, and dry stools. Modern research shows that it can shorten the time it takes to fall asleep, extend the duration of sleep, and has significant anticonvulsant effects.

It is also effective in treating heart disease and neurasthenia caused by Heart Qi Deficiency or Heart Blood Deficiency with a weak constitution.

Special Populations

Pregnancy

Use with caution during pregnancy. The modern Chinese Pharmacopoeia version contains several herbs of concern: Chuan Xiong (川芎, Ligusticum) is a Blood-invigorating herb that promotes circulation and could theoretically stimulate uterine activity; Rou Gui (肉桂, Cinnamon bark) is a strongly warming herb that moves Blood; and Zhu Sha (朱砂, cinnabar) contains mercury, which poses risks of fetal toxicity. The official drug labeling states that pregnant women should only use this formula under medical supervision. As a general precaution, pregnant women should avoid this formula unless specifically prescribed by a qualified practitioner who has weighed the risks and benefits.

Breastfeeding

The modern Pharmacopoeia version of this formula contains Zhu Sha (cinnabar), a mineral containing mercuric sulfide. Mercury can potentially transfer into breast milk, posing a risk to the nursing infant's developing nervous system. For this reason, breastfeeding women should avoid the cinnabar-containing version or use it only under close medical supervision for short durations. The classical version (without cinnabar) is generally considered more appropriate during breastfeeding, though caution is still advised as the Blood-moving herb Chuan Xiong (in the modern version) may also theoretically affect lactation. Consult a qualified practitioner before use.

Pediatric Use

This formula is not routinely recommended for young children. The official drug labeling for the modern version states that children should only use it under medical supervision and with an adult present. If a practitioner deems it appropriate for an older child (generally over 6 years), dosage should be reduced to approximately one-third to one-half of the adult dose, depending on the child's age and weight. The cinnabar (Zhu Sha) content in the modern version is of particular concern for children, as developing nervous systems are more vulnerable to mercury exposure. For pediatric sleep or anxiety issues, practitioners generally prefer milder formulas without mineral ingredients.

Drug Interactions

Cinnabar (Zhu Sha) interactions (modern Pharmacopoeia version only): The mercury in cinnabar must not be taken concurrently with bromide or iodide medications, as these can form toxic mercury compounds in the gut. Long-term use alongside any medication that is metabolized through or affects kidney function warrants monitoring, as mercury accumulation may compound nephrotoxic effects.

Gan Cao (Licorice root) interactions: The Zhi Gan Cao in this formula may interact with cardiac glycosides (digoxin) by promoting potassium loss, increasing the risk of toxicity. It may also interfere with corticosteroids (enhancing their effects and side effects), diuretics (compounding potassium depletion), and antihypertensives (due to its potential to cause sodium and water retention).

Dang Gui and Chuan Xiong interactions: Both herbs have mild Blood-invigorating properties that may potentiate the effects of anticoagulants and antiplatelet drugs (e.g. warfarin, aspirin, clopidogrel), potentially increasing bleeding risk.

Sedative interactions: The formula has demonstrated sedative and hypnotic effects in animal studies. It may potentiate the effects of benzodiazepines, barbiturates, and other CNS depressants, leading to excessive drowsiness.

Contraindications

Avoid

Yin deficiency with Fire (阴虚火旺): This formula is warming in nature and contains Qi-tonifying and Blood-moving herbs. People showing signs of Yin-deficient Heat such as flushed cheeks, hot palms and soles, night sweats with a red tongue and scanty coating, or a rapid thin pulse should not use this formula, as it may worsen the internal Heat.

Avoid

Liver Yang rising (肝阳上亢): People experiencing headaches, dizziness, irritability, tinnitus, and a bitter taste in the mouth due to Liver Yang rising should not use this formula. The warm, tonifying nature of the formula may aggravate these upward-surging symptoms.

Avoid

Active external pathogen invasion (acute cold, flu, or febrile illness): Tonifying formulas like this one can trap pathogens inside the body during the early stages of an acute infection. Use should be suspended until the external condition is fully resolved.

Caution

Spleen deficiency with loose stools or diarrhea: The formula contains several rich, cloying herbs (particularly in the classical version with Shu Di Huang and Gou Qi Zi; or in the modern version with heavy doses of Dang Gui and Bai Zi Ren) that may overwhelm a weak digestive system. Use with caution and consider adding Spleen-supporting herbs.

Caution

Phlegm-Dampness obstruction: If insomnia or palpitations are caused primarily by Phlegm-Dampness (marked by a thick greasy tongue coating, chest stuffiness, nausea), this formula's nourishing nature is not appropriate and may worsen the condition.

Caution

The modern Pharmacopoeia version contains Zhu Sha (cinnabar/mercuric sulfide). Due to mercury content, this version must not be taken long-term or in excessive doses. It should not be taken concurrently with bromide or iodide medications.

Cautions & Warnings

This formula is typically safe for most individuals, but it can lead to side effects in some cases. Patients with Liver Yang Rising should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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