Herb

Yin Xing Ye

Ginkgo leaf | 银杏叶

Also known as:

Bai Guo Ye (白果叶)

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Herb

Traditional Chinese Medicine background and properties

Herb Description

Ginkgo leaf is one of the most widely researched herbs in the world, prized for its ability to promote healthy blood circulation, particularly to the heart and brain. It is commonly used for chest pain, dizziness, poor memory, and high cholesterol. Its neutral temperature makes it gentle enough for most body types.

Herb Category

Main Actions

  • Invigorates Blood and Dispels Stasis
  • Unblocks the Channels and Alleviates Pain
  • Astringes the Lungs and calms wheezing
  • Transforms Turbidity and Lowers Lipids

How These Actions Work

'Activates Blood and resolves stasis' means Ginkgo leaf helps move Blood that has become sluggish or stuck in the vessels. In TCM, when Blood does not flow smoothly, it can cause chest pain, numbness, or sharp stabbing pains. This herb is especially valued for promoting circulation through the Heart vessels, making it a primary choice for chest tightness and pain from Blood stasis obstructing the collaterals.

'Unblocks collaterals and stops pain' refers to the herb's ability to open up the smaller, finer channels in the body. This is particularly relevant after stroke (where paralysis or weakness on one side indicates blocked collaterals) and for headache, dizziness, and poor circulation to the extremities.

'Astringes the Lungs and calms wheezing' means it gathers and firms up weakened Lung Qi. When the Lungs are deficient, Qi can leak outward, causing chronic cough and wheezing. The astringent property of Ginkgo leaf helps contain Lung Qi and reduce breathlessness. This action comes from its astringent and bitter tastes.

'Resolves turbidity and lowers lipids' is a modern TCM description reflecting its clinical use for high cholesterol and elevated blood lipids. 'Turbidity' in TCM refers to thick, sluggish substances that cloud the blood vessels, and this herb helps clear them away.

Patterns Addressed

In TCM, symptoms cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Yin Xing Ye is traditionally associated with these specific patterns.

The following describes this herb's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Yin Xing Ye addresses this pattern

Ginkgo leaf's primary action of activating Blood and resolving stasis directly addresses the core pathomechanism of this pattern, where Blood circulation through the Heart vessels becomes obstructed. Its sweet taste gently tonifies while its bitter taste helps move stagnation downward and outward. Entering the Heart channel, it reaches the site of obstruction directly, promoting blood flow through narrowed or blocked chest vessels. Its collateral-unblocking action is especially valuable because chest pain (xiōng bì, or chest impediment) often involves obstruction in the fine collateral network around the Heart.

A practitioner would look for one or more of these signs

Chest Pain

Stabbing or fixed chest pain, often worse with exertion

Chest Stiffness

Oppressive feeling in the chest

Palpitations

Irregular or forceful heartbeat accompanying chest discomfort

Purple Lips

Purplish discoloration of the lips indicating Blood stasis

TCM Properties

Temperature

Neutral

Taste

Sweet (甘 gān), Bitter (苦 kǔ), Astringent (涩 sè)

Channels Entered
Heart Lungs
Parts Used

Leaf (叶 yè)

This is partial information on the herb's TCM properties. More detailed information is available on the herb's dedicated page

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Botanical & Sourcing

Quality Indicators

Good quality dried ginkgo leaves should be relatively intact, fan-shaped, 3-12 cm long and 5-15 cm wide, yellowish-green or light brownish-yellow in color. The distinctive dichotomous (forked) parallel venation should be clearly visible. The surface should be smooth and hairless, and the leaves should tear easily along the longitudinal veins. The texture is light. The smell should be faint and the taste slightly bitter. Avoid leaves that are excessively brown, moldy, or heavily fragmented. For extract products, ensure pharmaceutical-grade standardization with total flavonoid glycosides of 24% or above, terpene lactones of 6% or above, and ginkgolic acid below 5 ppm.

Primary Growing Regions

Ginkgo originated in southern China and is now cultivated widely across the country, from Liaoning in the north to Guangdong in the south, and from Zhejiang in the east to Shaanxi, Gansu, Sichuan, Guizhou, and Yunnan in the west. Historically, the Ben Cao Gang Mu noted that ginkgo from the Xuancheng area of Anhui (宣城) produced the finest quality. Today, major production regions for medicinal ginkgo leaf include Jiangsu (particularly Taixing and Pizhou), Shandong, Zhejiang, Anhui, and Guangxi provinces. China accounts for approximately 70% of the world's ginkgo resources.

Harvesting Season

Autumn, while the leaves are still green (before they turn fully yellow), then dried promptly.

Supplier Information

Treasure of the East

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Miscellaneous Info

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Usage & Safety

How to use this herb and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This herb is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Traditional Dosage Reference

Standard

9-12g

Maximum

Up to 15g in decoction under practitioner supervision. For standardized extracts (EGb 761 type), do not exceed 240 mg/day.

Notes

The standard decoction dose is 9-12g. Ginkgo leaf is also commonly used as a standardized extract in tablet, capsule, or injection form rather than traditional decoction. When using extract preparations, typical dosing is 120-240 mg/day of a standardized extract (containing 24% flavonoid glycosides and 6% terpene lactones). For cardiovascular conditions (chest pain, high blood lipids), the higher end of the range may be used. For mild cognitive support or peripheral circulation, moderate doses suffice. Elderly patients on multiple medications should start at lower doses and be monitored for interactions.

Toxicity Classification

Slightly toxic

Raw, unprocessed ginkgo leaves contain ginkgolic acid (银杏酸) at concentrations of 3000-4000 ppm, which is water-soluble and toxic. Ginkgolic acid has cytotoxic, immunotoxic, and allergenic properties, and can cause neurological symptoms (nerve paralysis, paroxysmal spasms), gastrointestinal distress, and severe contact dermatitis. Because ginkgolic acid dissolves readily in water, simply steeping raw leaves as tea can cause poisoning rather than therapeutic benefit. Pharmaceutical-grade ginkgo leaf extracts must limit ginkgolic acid to less than 5 ppm per Chinese, European, and US Pharmacopoeia standards. Some advanced preparations reduce it to below 1 ppm. Proper standardized extraction removes the toxic ginkgolic acid while concentrating the beneficial flavonoids (24%) and terpene lactones (6%). Never use raw ginkgo leaves collected from trees without proper pharmaceutical processing.

Contraindications

Avoid

Active bleeding or bleeding disorders. Yin Xing Ye has blood-activating and antiplatelet properties that may worsen hemorrhage.

Caution

Concurrent use with anticoagulant or antiplatelet medications (warfarin, aspirin, clopidogrel) without medical supervision, due to increased bleeding risk.

Caution

Scheduled surgery within 1-2 weeks. Discontinue before elective procedures due to potential antiplatelet effects.

Caution

Epilepsy or seizure disorders. Large amounts of ginkgo may lower the seizure threshold and reduce the effectiveness of anticonvulsant medications.

Avoid

Known allergy to Ginkgo biloba or ginkgolic acid. Unprocessed or poorly standardized leaf preparations contain high levels of allergenic ginkgolic acid (up to 3000-4000 ppm), which can cause severe allergic reactions including contact dermatitis.

Caution

Patterns of excess (实邪). Classical texts note that those with excess pathogens should avoid this herb, as its astringent nature may trap pathogens inside.

Avoid

Direct use of raw, unprocessed leaves as tea. Raw ginkgo leaves contain high concentrations of water-soluble ginkgolic acid, which is toxic and can cause neurological symptoms.

Special Populations

Pregnancy

Use with caution during pregnancy. Ginkgo leaf has blood-activating and stasis-resolving properties that could theoretically increase bleeding risk, which is concerning during pregnancy and especially around delivery. Additionally, ginkgolic acid in poorly processed preparations may pose a toxicity risk. There are insufficient human safety studies in pregnant women. Avoid unless specifically prescribed and supervised by a qualified practitioner.

Breastfeeding

Insufficient safety data exists for ginkgo leaf use during breastfeeding. The antiplatelet activity of ginkgo compounds raises theoretical concerns about transfer through breast milk, and the potential allergenic effects of ginkgolic acid are a concern for nursing infants. Avoid use while breastfeeding unless under qualified practitioner supervision.

Pediatric Use

Limited safety data exists for pediatric use of ginkgo leaf. Classical texts mention external application of ginkgo leaf decoction for childhood intestinal inflammation (applied to hands, feet, and chest), using 3-9g. Internal use in children should be approached with caution, at reduced doses proportional to age and body weight, and only under qualified practitioner supervision. Not recommended for very young children without specific clinical indication.

Drug Interactions

Anticoagulants and antiplatelet drugs: Ginkgo leaf has platelet-activating factor (PAF) inhibiting activity and may increase bleeding risk when combined with warfarin, aspirin, clopidogrel, heparin, or direct oral anticoagulants. Monitor closely if co-administration is unavoidable.

NSAIDs: Concurrent use with ibuprofen, celecoxib, loxoprofen and similar drugs may increase the risk of bleeding due to additive antiplatelet effects.

Anticonvulsants: Ginkgo may lower the seizure threshold and reduce the effectiveness of anticonvulsant medications such as valproic acid and carbamazepine.

CYP enzyme substrates: At doses above 240 mg/day, ginkgo extract may weakly induce CYP2C19 (potentially reducing the effectiveness of omeprazole and similar proton pump inhibitors) and weakly inhibit CYP3A4 (potentially increasing levels of midazolam, nifedipine, and some statins such as simvastatin and atorvastatin).

Alprazolam: Ginkgo may reduce the effectiveness of alprazolam (Xanax).

Antidepressants (SSRIs/SNRIs): Combined use with fluoxetine, sertraline, or similar drugs may theoretically increase bleeding risk due to additive effects on platelet function.

Diabetes medications: Ginkgo may alter glucose metabolism, potentially affecting the response to oral hypoglycemic agents.

Dietary Advice

No specific strong dietary restrictions apply. However, since ginkgo leaf activates blood circulation and has mild antiplatelet effects, it is prudent to avoid excessive intake of other blood-thinning foods and supplements (such as large amounts of garlic, ginger, fish oil, or vitamin E) while taking ginkgo leaf preparations. Avoid alcohol in excess, as it may compound the effects on blood circulation and increase the risk of bleeding or headache.

Cautions & Warnings

Although this herb is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.