Liquorice (Gan Cao) Unprepared Rehmannia (Di Huang) Ginseng (Ren Shen) Cinnamon twigs (Gui Zhi) Dwarf lilyturf roots (Mai Dong) Donkey-hide gelatin (E Jiao) Hemp seeds (Huo Ma Ren) Fresh ginger (Sheng Jiang)

Chinese: 炙甘草汤

Pinyin: Zhì Gān Cǎo Tāng

Other names: Prepared Licorice Decoction,

Number of ingredients: 10 herbs

Formula category: Formulas that tonify Qi and Blood

Conditions for which it may be prescribed: AnemiaAtrial flutterHyperthyroidism and seven other conditions

  1. Augments the Qi
  2. Nourishes Yin
  3. Nourishes the Blood
  4. Restores the pulse

Contraindications: This formula is not recommended for use in its unmodified form in situations... This formula is not recommended for use in its unmodified form in situations where there is Heat due to Yin Deficiency or when severe diarrhea is present. see more

Source date: 220 AD

Source book: Discussion of Cold Damage

Zhi Gan Cao Tang is a 10-ingredient Chinese Medicine formula with Liquorice (Gan Cao) as a principal ingredient.

Invented in 220 AD, it belongs to the category of formulas that tonify Qi and Blood. Its main actions are: 1) augments the Qi and 2) nourishes Yin.

In Chinese Medicine health conditions are thought to arise due to "disharmonies" in the body as a system. These disharmonies are called "patterns" and the very purpose of herbal formulas is to fight them in order to restore the body's harmony.

In this case Zhi Gan Cao Tang is used by TCM practitioners to fight patterns like Lung Qi Deficiency or Qi and Blood Deficiency. From a Western Medicine standpoint, such patterns can give rise to a range of conditions such as irregular heartbeats, sick sinus syndrome or atrial flutter for instance.

On this page, after a detailed description of each of the ten ingredients in Zhi Gan Cao Tang, we review the patterns and conditions that Zhi Gan Cao Tang helps treat.

The ten ingredients in Zhi Gan Cao Tang

Gan Cao is a king ingredient in Zhi Gan Cao Tang. Like the name indicates, it means it has more power than other ingredients in the formula.

1. Liquorice (Gan Cao)

Part used: Dried root and rhizome

Nature: Neutral

Taste(s): Sweet

Meridian affinity: HeartLungSpleenStomach

Category: Tonic herbs for Qi Deficiency

Gan Cao augments the Qi of the Middle Burner. Liquorice used here is pan fried with honey , thus it is more effective than the raw Liquorice in nourishing the Heart and restoring the heartbeat.

Learn more about Liquorice (Gan Cao)

Di Huang is a deputy ingredient in Zhi Gan Cao Tang. This means it helps the king ingredient(s) treat the main pattern or it serves to treat a coexisting pattern.

2. Unprepared Rehmannia (Di Huang)

Part used: Prepared dried root tuber

Nature: Cold

Taste(s): Sweet

Meridian affinity: HeartKidneyLiver

Category: Herbs that cool the Blood

Di Huang sweet and cooling. It enriches and moistens so as to restore the Heart Yin and tonifies the Blood. Together with Zhi Gan Cao, it fills the vessels with Qi and Body Fluids, providing the basis for returning the pulse to its normal status.

Learn more about Unprepared Rehmannia (Di Huang)

Ren Shen is an assistant ingredient in Zhi Gan Cao Tang. This means that it either serves to reinforces the effect of other ingredients or it moderates their toxicity.

3. Ginseng (Ren Shen)

Part used: Dried root

Nature: Warm

Taste(s): BitterSweet

Meridian affinity: HeartLungSpleen

Category: Tonic herbs for Qi Deficiency

Ren Shen strongly tonifies the Original Qi and thus all of the Organs. It also calms the Mind, which relieves the palpitations and anxiety, especially when combined with the chief ingredient. It assists the king ingredient Zhi Gan Cao in tonifying the Qi of the Spleen and Stomach (the Post-Heaven Qi), which is the root of the Heart Qi and the source of Blood generation.

Learn more about Ginseng (Ren Shen)

Gui Zhi is an assistant ingredient in Zhi Gan Cao Tang. This means that it either serves to reinforces the effect of other ingredients or it moderates their toxicity.

4. Cinnamon Twigs (Gui Zhi)

Part used: Dried young branches

Nature: Warm

Taste(s): PungentSweet

Meridian affinity: HeartLungSpleen

Category: Warm/Acrid herbs that release the Exterior

Gui Zhi unblocks the flow of Heart Qi. Its combination with Ren Shen strengthens this effect. This is an important aspect of the treatment of palpitations, and Gui Zhi is found in every formula devised by Zhang Zhong-Jing for treating this symptom.

Learn more about Cinnamon Twigs (Gui Zhi)

Mai Dong is an assistant ingredient in Zhi Gan Cao Tang. This means that it either serves to reinforces the effect of other ingredients or it moderates their toxicity.

5. Dwarf Lilyturf Roots (Mai Dong)

Part used: Dried root tuber

Nature: Cool

Taste(s): BitterSweet

Meridian affinity: HeartLungStomach

Category: Tonic herbs for Yin Deficiency

Mai Dong moistens Dryness in the Stomach and Lungs, which is thte Upper Burner. The combination of E Jiao, Huo Ma Ren and Mai Dong assists Sheng Di Huang in enriching the Yin, moistening Dryness, and cooling
Heat from Yin Deficiency.

Learn more about Dwarf Lilyturf Roots (Mai Dong)

E Jiao is an assistant ingredient in Zhi Gan Cao Tang. This means that it either serves to reinforces the effect of other ingredients or it moderates their toxicity.

6. Donkey-Hide Gelatin (E Jiao)

Part used: Solid glue prepared from the dried or fresh skin of donkeys

Nature: Neutral

Taste(s): Sweet

Meridian affinity: KidneyLiverLung

Category: Herbs that invigorate the Blood

E Jiao effectively enriches the Yin, tonifies the Blood, and moistens Dryness. The combination of E Jiao, Huo Ma Ren and Mai Dong assists Sheng Di Huang in enriching the Yin, moistening Dryness, and cooling
Heat from Yin Deficiency.

Learn more about Donkey-Hide Gelatin (E Jiao)

Huo Ma Ren is an assistant ingredient in Zhi Gan Cao Tang. This means that it either serves to reinforces the effect of other ingredients or it moderates their toxicity.

7. Hemp Seeds (Huo Ma Ren)

Part used: Dried ripe fruit

Nature: Neutral

Taste(s): Sweet

Meridian affinity: Large intestineSpleenStomach

Category: Laxative herbs that drain downward

Huo Ma Ren nourishes the Yin and moistens the Intestines, which is located at the Lower Burner. The combination of E Jiao, Huo Ma Ren and Mai Dong assists Sheng Di Huang in enriching the Yin, moistening Dryness, and cooling
Heat from Yin Deficiency.

Learn more about Hemp Seeds (Huo Ma Ren)

Sheng Jiang is an assistant ingredient in Zhi Gan Cao Tang. This means that it either serves to reinforces the effect of other ingredients or it moderates their toxicity.

8. Fresh Ginger (Sheng Jiang)

Part used: Fresh root

Nature: Warm

Taste(s): Pungent

Meridian affinity: LungSpleenStomach

Category: Warm/Acrid herbs that release the Exterior

Sheng Jiang strengthens the Stomach and enable it to cope with the tonifying substances in the formula. In concert with Da Zao, it also regulates the relationship between the Protective and Nutritive Qi. This function plays an important part in restoring vitality to individuals suffering from consumption, as it enables their systems to revive without developing other problems.

Learn more about Fresh Ginger (Sheng Jiang)

Da Zao is an assistant ingredient in Zhi Gan Cao Tang. This means that it either serves to reinforces the effect of other ingredients or it moderates their toxicity.

9. Jujube Dates (Da Zao)

Part used: Dried ripe fruit

Nature: Warm

Taste(s): Sweet

Meridian affinity: SpleenStomach

Category: Tonic herbs for Qi Deficiency

Da Zao benefits the Spleen and nourishes the Heart. It assists the king ingredient Zhi Gan Cao in tonifying the Qi of the Spleen and Stomach (the Post-Heaven Qi), which is the root of the Heart Qi and the source of Blood generation.

Learn more about Jujube Dates (Da Zao)

Mi Jiu is an envoy ingredient in Zhi Gan Cao Tang. This means that it directs the formula towards certain area of the body and/or harmonizes the actions of other ingredients.

10. Rice Wine (Mi Jiu)

Part used: Fermented rice

Nature: Hot

Taste(s): BitterPungentSweet

Meridian affinity: Liver

Category: Herbs that invigorate the Blood

Mi Jiu helping the assistant ingredients keep things moving. Although this condition is due to an underlying Deficiency, there is also an element of Stagnation due to both Cold and Dryness. Both must be treated if the condition is to be dealt with effectively.

Learn more about Rice Wine (Mi Jiu)

Conditions and patterns for which Zhi Gan Cao Tang may be prescribed

It's important to remember that herbal formulas are meant to treat patterns, not "diseases" as understood in Western Medicine. According to Chinese Medicine patterns, which are disruptions to the body as a system, are the underlying root cause for diseases and conditions.

As such Zhi Gan Cao Tang is used by TCM practitioners to treat two different patterns which we describe below.

But before we delve into these patterns here is an overview of the Western conditions they're commonly associated with:

Irregular heartbeats Sick sinus syndrome Atrial flutter Atrial fibrillation Coronary artery disease Viral myocarditis Rheumatic heart disease Hyperthyroidism Anemia Upper GI bleeding secondary to cirrhosis

Again it wouldn't be correct to say "Zhi Gan Cao Tang treats irregular heartbeats" for instance. Rather, Zhi Gan Cao Tang is used to treat patterns that are sometimes the root cause behind irregular heartbeats.

Now let's look at the two patterns commonly treated with Zhi Gan Cao Tang.

The Lungs is a so-called "Zang" Organ. Learn more about the Lungs in Chinese Medicine

Lung Qi Deficiency

Zhi Gan Cao Tang is sometimes prescribed by TCM practitioners to treat Lung Qi Deficiency. This pattern leads to symptoms such as spontaneous daytime sweating, aversion to speak, shortness of breath and coughing. Patients with Lung Qi Deficiency typically exhibit empty (Xu) pulses as well as Pale or normal color tongue.

The Lungs govern Qi and respiration. Therefore there will be shortness of breath and coughing in case of Lung Qi Deficiency. However the condition is not severe as it is mostly on exertion and not full-blown symptoms of bronchitis or asthma.

Symptoms like coughing can also appear if Lungs' Qi... read more about Lung Qi Deficiency

Qi is one of Chinese Medicine's vital subtances. Learn more about Qi in Chinese Medicine

Qi and Blood Deficiency

Zhi Gan Cao Tang is sometimes prescribed by TCM practitioners to treat Qi and Blood Deficiency. This pattern leads to symptoms such as general weakness, fatigue, weak voice and pale face. Patients with Qi and Blood Deficiency typically exhibit slowed-down (Huan), weak (Ruo) or fine (Xi) pulses as well as Pale tongue with thin white coating .

The Qi and Blood are from the some origin and these two elements are transformable between each other. The Qi creates the Blood, and vice versa the Blood supplies Qi. Therefore it is quite common both patterns appear at the same time. 

When general Qi is Deficient, the patients lack the energy to... read more about Qi and Blood Deficiency

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