Ding Chuan Tang

Arrest Wheezing Decoction · 定喘湯

Also known as: Bai Guo Ding Chuan Tang (白果定喘汤, Ginkgo Arrest Wheezing Decoction)

A classical formula used to relieve wheezing, coughing, and shortness of breath caused by phlegm-heat congesting the lungs, often triggered by catching a cold. It works by opening the airways, directing Lung Qi downward, clearing heat, and resolving thick, sticky phlegm. Commonly applied for asthma and bronchitis with yellow, difficult-to-expectorate sputum.

Origin Shè Shēng Zhòng Miào Fāng (摄生众妙方, Multitude of Marvelous Formulas for Sustaining Life) by Zhang Shiche — Míng dynasty, ~1550 CE
Composition 9 herbs
Bai Guo
King
Bai Guo
Ma Huang
King
Ma Huang
Zi Su Zi
Deputy
Zi Su Zi
Xing Ren
Deputy
Xing Ren
Ban Xia
Deputy
Ban Xia
Kuan Dong Hua
Deputy
Kuan Dong Hua
Sang Bai Pi
Assistant
Sang Bai Pi
Huang Qin
Assistant
Huang Qin
+1
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Ding Chuan Tang is designed to correct these specific patterns.

Why Ding Chuan Tang addresses this pattern

This is the primary pattern for Ding Chuan Tang. It arises when someone with a constitutional tendency toward excess phlegm catches a Wind-Cold pathogen. The cold constrains the exterior and blocks the Lung's ability to disperse and descend Qi. The blocked Qi stagnates and transforms into heat, which 'cooks' the existing phlegm into thick, sticky, yellow sputum. The formula addresses every layer of this pattern: Ma Huang releases the exterior Wind-Cold; Bai Guo, Zi Su Zi, Xing Ren, Ban Xia, and Kuan Dong Hua descend Qi and resolve phlegm; Huang Qin and Sang Bai Pi clear the interior heat. The result is that Lung Qi can once again flow freely, phlegm is dissolved, heat is cleared, and the exterior pathogen is expelled.

A practitioner would look for one or more of these signs

Wheezing

Wheezing and labored breathing, the hallmark symptom

Hypochondrial Pain That Is Worse On Coughing And Breathing

Coughing with copious thick, yellow sputum that is difficult to expectorate

Shortness Of Breath

Shortness of breath and rapid breathing

Chills

Mild aversion to cold or slight chills, indicating residual exterior pathogen

Yellowish Phlegm

Thick, sticky, yellow-colored sputum indicating phlegm-heat

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Ding Chuan Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, asthma (哮喘) is understood as a condition rooted in phlegm lodged deep within the Lungs. This 'hidden phlegm' (伏痰) sits dormant until triggered, commonly by external Wind-Cold, dietary factors, or emotional stress. Once triggered, the phlegm obstructs the airways and disrupts the Lung's normal function of dispersing and descending Qi. When blocked Qi stagnates and transforms into heat, it 'cooks' the phlegm into thick, yellow, sticky sputum, creating a self-reinforcing cycle of obstruction, heat, and more phlegm. The Lung becomes unable to perform its descending function, so Qi rebels upward, producing the characteristic wheezing and labored breathing.

Why Ding Chuan Tang Helps

Ding Chuan Tang is specifically designed for the phlegm-heat type of asthma attack. The formula works on multiple levels simultaneously: Ma Huang opens the blocked airways and restores Lung Qi flow, while Bai Guo prevents over-dispersion and directly arrests wheezing. The team of Zi Su Zi, Xing Ren, Ban Xia, and Kuan Dong Hua drives Qi downward and dissolves the thick phlegm, while Huang Qin and Sang Bai Pi clear the heat that keeps generating more sticky sputum. A randomized, double-blind clinical trial demonstrated that Ding Chuan Tang improved airway hyperresponsiveness in children with persistent asthma over 12 weeks of treatment. Animal research has shown it can reduce eosinophil infiltration and suppress the Th2 inflammatory response associated with allergic asthma.

Also commonly used for

Chronic Bronchitis

Acute episodes with yellow sputum and wheezing

Bronchiolitis

Especially in infants, with wheezing and phlegm

Hypochondrial Pain That Is Worse On Coughing And Breathing

Cough-variant asthma with thick phlegm

Wheezing

Acute wheezing episodes from various respiratory conditions

What This Formula Does

Every TCM formula has a specific set of actions — here's what Ding Chuan Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Ding Chuan Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Ding Chuan Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Ding Chuan Tang works at the root level.

Ding Chuan Tang addresses a very specific situation: a person who already has Phlegm-Heat brewing inside their Lungs catches an external chill (Wind-Cold). Think of it as a problem on two fronts at once.

The inner problem often comes first. Some people have a constitutional tendency to produce excessive Phlegm, perhaps from poor diet, lingering illness, or a weak digestive system that fails to properly transform fluids. This Phlegm accumulates in the Lungs. Over time, stagnant Phlegm generates Heat, much like compost heaps that build up warmth internally. The result is thick, sticky, yellowish mucus that clogs the airways.

Then the outer problem arrives. When such a person catches a chill, the cold tightens the body's surface and constricts the Lungs' ability to circulate Qi. The Lungs are supposed to spread and descend Qi smoothly, but now they are squeezed from the outside by cold and clogged from the inside by hot Phlegm. Lung Qi rebels upward, producing wheezing, coughing, and labored breathing. The classic signs are copious thick yellow sputum, a greasy yellow tongue coating, and a slippery rapid pulse, sometimes with mild chills and fever lingering from the surface invasion. The formula works by addressing both layers simultaneously: gently opening the exterior constraint while vigorously clearing the interior Phlegm-Heat and restoring the Lungs' natural downward flow of Qi.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Warm

Taste Profile

Predominantly bitter and acrid (pungent), with some sweet notes. The acrid taste disperses and opens the Lungs, the bitter taste descends Qi and dries Dampness, and the sweet taste harmonizes the formula.

Channels Entered

Ingredients

9 herbs

The herbs that make up Ding Chuan Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Bai Guo

Bai Guo

Ginkgo nuts

Dosage 9 - 12g
Temperature Neutral
Taste Bitter, Sweet
Organ Affinity Lungs
Preparation Remove shell, crush, and dry-fry until yellow (去壳砸碎炒黄)

Role in Ding Chuan Tang

Constrains Lung Qi to arrest wheezing, transforms phlegm, and prevents Ma Huang from over-dispersing. Its astringent nature balances the dispersing action of Ma Huang, creating a 'one scattering, one collecting' dynamic that powerfully stabilizes the airways.
Ma Huang

Ma Huang

Ephedra

Dosage 6 - 9g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Urinary Bladder, Lungs

Role in Ding Chuan Tang

Opens and disseminates Lung Qi, releases the exterior to dispel Wind-Cold, and arrests wheezing. As the other King herb, it addresses the external component of the pattern and restores the Lung's descending and dispersing functions.
Deputies — Assists and enhances the King
Zi Su Zi

Zi Su Zi

Perilla seeds

Dosage 6 - 9g
Temperature Warm
Taste Pungent
Organ Affinity Lungs

Role in Ding Chuan Tang

Directs Lung Qi downward, resolves phlegm, and stops wheezing. Reinforces the descending action needed to counter the upward rebellion of Lung Qi.
Xing Ren

Xing Ren

Apricot seeds

Dosage 4.5 - 9g
Temperature Warm
Taste Bitter, Sweet
Organ Affinity Large Intestine, Lungs
Preparation Remove skin and tip (去皮尖)

Role in Ding Chuan Tang

Descends Lung Qi and stops coughing. Works with Ma Huang in a classic pairing where Ma Huang opens and Xing Ren descends, restoring normal Lung Qi movement.
Ban Xia

Ban Xia

Crow-dipper rhizomes

Dosage 9g
Temperature Warm
Taste Pungent
Organ Affinity Lungs, Spleen, Stomach
Preparation Use the prepared form (法制半夏)

Role in Ding Chuan Tang

Dries Dampness and transforms phlegm, directs rebellious Qi downward, and harmonizes the Stomach. A key herb for resolving the sticky, accumulated phlegm obstructing the airways.
Kuan Dong Hua

Kuan Dong Hua

Coltsfoot flowers

Dosage 9g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Lungs

Role in Ding Chuan Tang

Moistens the Lungs, descends Qi, and stops coughing. Supports the phlegm-resolving and cough-suppressing actions of the other Deputy herbs.
Assistants — Supports or moderates other herbs
Sang Bai Pi

Sang Bai Pi

Mulberry bark

Dosage 6 - 9g
Temperature Cold
Taste Sweet
Organ Affinity Lungs
Preparation Use honey-processed form (蜜炙)

Role in Ding Chuan Tang

Drains Lung heat, descends Lung Qi, and promotes urination. Clears the interior heat that has transformed from constrained Qi, and works with Huang Qin to address the phlegm-heat component.
Huang Qin

Huang Qin

Baikal skullcap roots

Dosage 4.5 - 6g
Temperature Cold
Taste Bitter
Organ Affinity Gallbladder, Heart, Large Intestine, Lungs, Small Intestine, Spleen
Preparation Lightly dry-fried (微炒)

Role in Ding Chuan Tang

Clears heat from the Lungs, dries dampness, and stops coughing. Directly targets the phlegm-heat that produces thick yellow sputum, and prevents the warm, dispersing herbs from generating further heat.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Liquorice

Dosage 3g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Ding Chuan Tang

Harmonizes the actions of all the other herbs in the formula, moderates the harshness of the dispersing and descending ingredients, and protects the Stomach.

Why This Combination Works

How the herbs in Ding Chuan Tang complement each other

Overall strategy

This formula addresses a complex pattern where Wind-Cold traps the exterior while phlegm-heat brews in the interior, blocking the Lung's ability to properly disperse and descend Qi. The prescription strategy simultaneously releases the exterior, opens the Lung, descends rebellious Qi, clears heat, and resolves phlegm, all while preventing any single therapeutic direction from going too far.

King herbs

Ma Huang and Bai Guo serve as co-Kings in a brilliantly balanced pairing. Ma Huang is acrid and warm, opening the Lung and dispersing to release the exterior and stop wheezing. Bai Guo is astringent and constraining, gathering Lung Qi to arrest wheezing and prevent Ma Huang from over-scattering. Together they form a 'one scattering, one collecting' (一散一收) dynamic: Ma Huang ensures the Lung is not blocked, while Bai Guo ensures the Lung is not depleted. This mutual restraint amplifies their combined anti-wheezing power.

Deputy herbs

Four herbs reinforce the Kings by focusing on descending Qi and resolving phlegm. Zi Su Zi directs Lung Qi downward powerfully; Xing Ren descends Qi and stops coughing, partnering with Ma Huang to restore the Lung's natural rhythm of dispersing and descending. Fa Ban Xia dries dampness and transforms the thick, sticky phlegm that is the material basis of the obstruction. Kuan Dong Hua moistens the Lung and descends Qi, adding a gentle cough-suppressing quality that complements the drying action of Ban Xia.

Assistant herbs

Sang Bai Pi and Huang Qin serve as restraining Assistants. Both clear heat from the Lungs, directly targeting the phlegm-heat that produces the thick yellow sputum. Huang Qin also dries dampness, reinforcing Ban Xia's phlegm-resolving effect. Together they counterbalance the warm, dispersing nature of Ma Huang and the other acrid herbs, preventing the formula from generating more heat while treating the internal heat component that is central to the pattern.

Envoy herbs

Gan Cao harmonizes the entire formula, moderating the interaction between warm dispersing herbs and cold heat-clearing herbs. It also gently protects the Stomach from the drying and descending actions of the other ingredients.

Notable synergies

The Ma Huang and Bai Guo pairing is the signature of this formula, creating a dynamic tension between dispersion and containment that is more effective for wheezing than either approach alone. The Huang Qin and Sang Bai Pi pairing targets Lung heat from two angles: Huang Qin through bitter cold clearing and Sang Bai Pi through sweet cold draining. The Ma Huang and Xing Ren combination (from San Ao Tang) restores the Lung's dispersing-descending axis, while Ban Xia and Zi Su Zi work together to transform phlegm and direct Qi downward.

How to Prepare

Traditional preparation instructions for Ding Chuan Tang

Traditionally: add three cups (zhong) of water to the herbs, decoct down to two cups, and divide into two servings of one cup each. Sip slowly, at any time of day. Ginger is not added to this formula.

Modern method: Decoct all herbs in approximately 600–800 ml of water. Bring to a boil, then simmer for 30–40 minutes. Strain and divide into two doses, taken warm morning and evening.

Preparation notes for individual herbs: Bai Guo should be shelled, crushed, and dry-fried until yellow before adding. Xing Ren should have the skin and tip removed. Sang Bai Pi should be honey-processed (蜜炙). Huang Qin should be lightly dry-fried (微炒). Ban Xia should be prepared using the standard method (法制半夏).

Common Modifications

How practitioners adapt Ding Chuan Tang for specific situations

Added
Gua Lou

Gua Lou (瓜蒌), 12-15g, clears heat and loosens thick phlegm for easier expectoration

Dan Nan Xing

Dan Nan Xing (胆南星), 6-9g, clears heat and powerfully dissolves stubborn phlegm

When phlegm is extremely thick and tenacious, the base formula's phlegm-resolving capacity needs reinforcement. Gua Lou and Dan Nan Xing both clear heat-phlegm and promote expectoration of stubborn sputum.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Ding Chuan Tang should not be used or requires extra caution

Avoid

Externally contracted Wind-Cold without internal Phlegm-Heat: this formula is designed for a mixed pattern of exterior Cold with interior Phlegm-Heat. Using it for a pure Wind-Cold invasion (no sweating, no yellow phlegm, no signs of internal Heat) is inappropriate, as the Heat-clearing herbs would further damage already constrained Lung Qi.

Avoid

Chronic asthma with Qi Deficiency and a frail (weak) pulse: this formula is composed entirely of dispersing and draining herbs with no tonifying ingredients. In a person whose wheezing stems from underlying Qi weakness rather than excess Phlegm-Heat, it could further deplete their already insufficient Qi.

Avoid

Chronic wheezing or cough caused by Lung and Kidney Yin Deficiency: the warm, drying herbs (Ma Huang, Ban Xia) would further injure Yin fluids and worsen dry cough, night sweats, or heat sensations associated with Yin Deficiency patterns.

Caution

Dry cough without phlegm or with scant, sticky phlegm from Lung dryness: the formula's drying and dispersing properties are unsuitable when the Lungs lack moisture rather than being congested with Phlegm.

Caution

Hypertension, heart disease, or thyroid disorders: Ma Huang (Ephedra) contains sympathomimetic alkaloids that can raise blood pressure and heart rate. People with cardiovascular conditions should use this formula with extreme caution under close medical supervision.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Ma Huang (Ephedra) is a strong dispersing herb whose sympathomimetic alkaloids (ephedrine, pseudoephedrine) can stimulate the cardiovascular system and potentially affect uterine blood flow. Xing Ren (Apricot Kernel) contains small amounts of amygdalin. Ban Xia (Pinellia) is traditionally listed among herbs requiring caution in pregnancy due to its potent descending and drying nature. The NCCIH considers the use of ephedra during pregnancy unsafe. This formula should generally be avoided in pregnancy unless the clinical situation is urgent and no safer alternative exists, and only under close supervision by a qualified practitioner.

Breastfeeding

Use with caution during breastfeeding. Ma Huang (Ephedra) contains ephedrine and pseudoephedrine, which are known to pass into breast milk. These sympathomimetic compounds may cause irritability, poor sleep, or increased heart rate in nursing infants. Pseudoephedrine has also been documented to reduce milk supply in some mothers. If the formula is clinically necessary, the breastfeeding parent should be monitored for decreased lactation, and the infant should be observed for signs of stimulant effects (fussiness, poor feeding, disrupted sleep).

Children

Ding Chuan Tang has been used clinically in children and was specifically studied in a randomized controlled trial in children aged 8 to 15 at a dose of 6.0 g of concentrated granules daily for 12 weeks. For younger children (under 8), dosages are typically reduced proportionally based on age and body weight, often to one-third to one-half the adult dose. The formula has also been used in modified form for infants with acute bronchiolitis in Chinese clinical reports, though such use requires careful practitioner supervision. Bai Guo (Ginkgo nut) should be used within the prescribed dosage as excessive consumption can cause toxicity, particularly in young children. Ma Huang dosage should be conservative in pediatric patients to avoid overstimulation.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Ding Chuan Tang

Ma Huang (Ephedra) interactions: This is the primary concern. Ma Huang contains ephedrine and pseudoephedrine, which are sympathomimetic agents. It may interact with:

  • MAO inhibitors (e.g. phenelzine, tranylcypromine): Concurrent use can cause dangerous hypertensive crisis. This is a serious and well-documented interaction.
  • Beta-blockers and antihypertensives: Ephedrine can oppose the blood-pressure-lowering effects of these drugs.
  • Cardiac glycosides (e.g. digoxin): Increased risk of cardiac arrhythmias due to additive sympathomimetic stimulation.
  • Theophylline and other bronchodilators: Potential for additive stimulant effects on the heart and central nervous system.
  • Other stimulants (caffeine, amphetamines, decongestants containing pseudoephedrine): Additive cardiovascular and CNS stimulation.

Gan Cao (Licorice root) interactions: Glycyrrhizin in Gan Cao can cause potassium depletion and sodium retention with prolonged use. This may interact with diuretics, corticosteroids, digoxin, and antihypertensive medications.

Huang Qin (Scutellaria) interactions: Baicalin may affect the absorption of certain drugs and has been shown to inhibit some CYP450 enzymes, potentially altering the metabolism of concurrently administered medications.

Usage Guidance

Practical advice for getting the most out of Ding Chuan Tang

Best time to take

As the original text states, 'not restricted by time' (不拘时候). Typically taken warm, sipped slowly (徐徐服), twice daily between meals.

Typical duration

Acute use: 3-10 days during active wheezing episodes, reassessed as symptoms change.

Dietary advice

Avoid cold, raw foods and iced drinks, which can constrict the Lungs and worsen Phlegm accumulation. Also avoid greasy, fried, and rich foods, as these generate Dampness and Phlegm. Reduce intake of excessively spicy or hot foods, which may aggravate the internal Heat component. Dairy products and overly sweet foods should be minimized as they tend to promote Phlegm production. Suitable foods include steamed pears with rock sugar (to moisten the Lungs), white radish soup (to transform Phlegm), and light, easily digested warm meals like congee with lily bulb.

Ding Chuan Tang originates from Shè Shēng Zhòng Miào Fāng (摄生众妙方, Multitude of Marvelous Formulas for Sustaining Life) by Zhang Shiche Míng dynasty, ~1550 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Ding Chuan Tang and its clinical use

Original indication from the She Sheng Zhong Miao Fang (《摄生众妙方》):

The original text records the formula's use and preparation: 「水三盅,煎二盅,作二服,每服一盅,不用姜,不拘时候,徐徐服。」 ("Decoct with three cups of water down to two cups. Divide into two doses, one cup each. Do not add ginger. Take at any time, sipping slowly.")

The instruction "do not add ginger" (不用姜) is noteworthy. Ginger is routinely added to decoctions to assist the exterior-releasing function of herbs like Ma Huang. Its deliberate exclusion here suggests the formula's primary therapeutic focus is on the interior Phlegm-Heat, with the exterior-releasing action being secondary.

Formula verse (方歌):

「定喘白果与麻黄,苏子夏款杏草囊,清热泻火桑白芩,宣肺平喘效力彰。」

("Ding Chuan uses Bai Guo and Ma Huang, Su Zi, Ban Xia, Kuan Dong Hua, Xing Ren, and Gan Cao in company; Sang Bai Pi and Huang Qin clear Heat and drain Fire; disseminating the Lungs and calming wheezing, its efficacy is manifest.")

Historical Context

How Ding Chuan Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Ding Chuan Tang first appeared in the She Sheng Zhong Miao Fang (《摄生众妙方》, "Multitude of Marvelous Formulas for Sustaining Life"), compiled by the Ming dynasty scholar Zhang Shiche (张时彻) around 1550 CE. The book is a collection of effective folk and clinical prescriptions rather than an original theoretical treatise, and the actual creator of the formula is unknown. As one commentator notes, "we cannot know the author or original intent" of this formula, only that it "came from folk practice and had miraculous effects for wheezing."

The formula is also known as Bai Guo Ding Chuan Tang (白果定喘汤, "Ginkgo Arrest Wheezing Decoction"), a name recorded in the Li Shi Yi Jian (《李氏医鉴》). A modified version later appeared in the Chong Ding Tong Su Shang Han Lun (《重订通俗伤寒论》), which added Chen Pi (tangerine peel) to the composition.

Modern scholars have noted that the formula's structure can be understood as a combination of San Ao Tang (the Ma Huang, Xing Ren, and Gan Cao core for opening the Lungs) merged with Phlegm-clearing and Lung-astringing herbs. The distinctive addition of Bai Guo and Kuan Dong Hua together has been described as giving the formula its characteristic "wheezing-arresting" power, acting as what classical physicians called "robbing herbs" (劫药) that powerfully halt the acute symptom.

Modern Research

4 published studies investigating the pharmacological effects or clinical outcomes of Ding Chuan Tang

1

Randomized, double-blind, placebo-controlled clinical trial of DCT for airway hyper-responsiveness in asthmatic children (2006)

Chan CK, Kuo ML, Shen JJ, See LC, Chang HH, Huang JL. Pediatric Allergy and Immunology, 2006, 17(5): 316-322.

This trial enrolled 52 children aged 8 to 15 with mild to moderate persistent asthma. Participants received either 6.0 g of Ding Chuan Tang or placebo daily for 12 weeks. The study found that DCT improved airway hyper-responsiveness and symptom and medication scores compared to placebo.

Link
2

Preclinical study: DCT attenuates airway inflammation and eosinophil infiltration in ovalbumin-sensitized asthmatic mice (2021)

Ma J, Liu MX, Chen LC, Shen JJ, Kuo ML. BioMed Research International, 2021, 2021: 6692772.

Using an OVA-sensitized mouse asthma model, this study showed that DCT significantly reduced airway hyper-responsiveness, eosinophil infiltration, and mucus production. It also reduced Th2 cytokines IL-5 and IL-13, suggesting DCT may alleviate allergic asthma through suppression of Th2-mediated immune responses.

Link
3

Preclinical study: Effects of DCT on bronchoconstriction and airway leukocyte infiltration in sensitized guinea pigs (2004)

Kao ST, Chang CH, Chen YS, Chiang SY, Lin JG. Immunopharmacology and Immunotoxicology, 2004, 26(1): 113-124.

This guinea pig study investigated DCT's antiasthmatic mechanisms using three different dosing protocols. DCT significantly inhibited immediate and late asthmatic responses, caused concentration-dependent relaxation of tracheal smooth muscle, and suppressed eosinophil infiltration into the airways, demonstrating both bronchodilatory and anti-inflammatory properties.

PubMed
4

Network pharmacology study: Molecular docking and network connections of active compounds from DCT (2020)

Kelly-Cirino C. PeerJ, 2020, 8: e8685.

This computational study used molecular docking and network pharmacology to identify potential anti-asthma mechanisms of DCT. It found that DCT compounds interact with five key asthma-related protein targets (ESR1, KDR, LTA4H, PDE4D, and PPARG) involved in inflammation and immune signaling pathways.

PubMed

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.