Formula

Suan Zao Ren Tang

Sour Jujube Decoction | 酸枣仁汤

Also known as:

Good Night Blend , Zizyphus Decoction

Properties

Spirit-calming formulas · Slightly Cool

Key Ingredients

Suan Zao Ren

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula for difficulty sleeping caused by insufficient nourishment of the Liver and Heart. It works by replenishing Blood to calm the mind while gently clearing the low-grade internal heat that causes restlessness, irritability, and night sweats. One of the most widely used sleep formulas in Chinese medicine for over 1,800 years.

Formula Category

Main Actions

  • Nourishes Blood and Calms the Spirit
  • Clears deficiency Heat and eliminates irritability
  • Nourishes Liver Blood
  • Calms the Heart and Quiets the Spirit
  • Harmonizes the Liver and Spleen

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Suan Zao Ren Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Suan Zao Ren Tang addresses this pattern

Liver Blood deficiency is the primary pattern this formula addresses. When Liver Blood is insufficient, the Ethereal Soul (Hun) loses its anchor and wanders at night, causing difficulty falling asleep, excessive dreaming, and restless sleep. The Heart, which depends on Blood nourishment to house the Spirit (Shen), also becomes unsettled. Suan Zao Ren directly nourishes Liver Blood and calms the Spirit, while Chuan Xiong ensures Blood circulates smoothly through the Liver. Fu Ling calms the Heart, and Gan Cao supplements the middle to support Blood production. The entire formula is built around restoring the Liver's Blood reserves so the Hun can settle and sleep can return.

A practitioner would look for one or more of these signs

Insomnia

Difficulty falling asleep or staying asleep, often worsening with fatigue

Palpitations

Heart palpitations, especially at night or when lying down

Dizziness

Dizziness and light-headedness from insufficient Blood reaching the head

Blurry Vision

Blurred or dry vision, floaters

Anxiety

A vague sense of unease or restlessness that worsens in the evening

How It Addresses the Root Cause

Suan Zao Ren Tang addresses a pattern rooted in Liver Blood deficiency generating internal deficiency Heat that disturbs the spirit. In TCM, the Liver stores Blood and houses the ethereal soul (Hun). When Liver Blood becomes depleted, often through prolonged illness, overwork, excessive worry, or chronic strain, two consequences follow. First, the Blood can no longer nourish the Heart, which depends on sufficient Blood to house and anchor the spirit (Shen). A spirit without a stable home becomes restless. Second, when Blood and Yin are insufficient, they fail to restrain the body's Yang, which rises unchecked and generates empty Heat. This low-grade internal warmth is not a robust fever but a smoldering irritability that worsens at night when the body should be settling into stillness.

Night is the domain of Yin. Sleep depends on Yang Qi descending inward and being embraced by Yin. When Yin-Blood is depleted and deficiency Heat simmers, Yang cannot settle, and the mind remains agitated. This produces the hallmark presentation: restless insomnia with mental agitation, palpitations, dizziness, dry throat, a red tongue, and a thin wiry pulse. The dryness and Heat signs are mild because they arise from insufficiency rather than excess. The formula works because it simultaneously replenishes the Blood that anchors the spirit, clears the mild Heat that agitates it, and harmonizes the Liver so its Qi flows smoothly rather than generating further internal tension.

Formula Properties

Temperature

Slightly Cool

Taste Profile

Predominantly sweet and sour with mild bitter notes: sweet and sour to nourish and astringe Liver Blood, bitter to clear deficiency Heat.

Target Organs
Heart Liver Gallbladder Kidneys
Channels Entered
Heart Liver Gallbladder Kidney

Formula Origin

Jin Gui Yao Lue (金匮要略, Essential Prescriptions from the Golden Cabinet) by Zhang Zhongjing

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Suan Zao Ren Tang

Detailed information about each herb in Suan Zao Ren Tang and their roles

Kings
Deputies
Assistants
Envoys
Suan Zao Ren
Suan Zao Ren

Sour jujube seed

Dosage: 15 - 30g

Temperature Neutral
Taste Sweet (甘 gān), Sour (酸 suān)
Organ Affinity Heart, Liver, Gallbladder
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Suan Zao Ren Tang

The principal herb, used in a heavy dose to nourish Liver Blood, calm the Heart, and quiet the Spirit (Shen). Its sweet and sour flavours enter the Heart and Liver channels, replenishing Blood to anchor the Ethereal Soul (Hun) and promote sleep.

Fu Ling
Fu Ling

Poria

Dosage: 6 - 15g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Suan Zao Ren Tang

Calms the Heart and quiets the Spirit while strengthening the Spleen. Supports the King herb by promoting tranquility from within and helping to transform any dampness that might obstruct the Spirit.

Zhi Mu
Zhi Mu

Anemarrhena rhizome

Dosage: 6 - 12g

Temperature Cold
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Lungs, Stomach, Kidneys
Parts Used Rhizome (根茎 gēn jīng)
Role in Suan Zao Ren Tang

Nourishes Yin and clears deficiency Heat. Its bitter, cold, and moistening nature directly addresses the internal heat generated by Blood and Yin insufficiency, relieving the restlessness and irritability that disturb sleep.

Chuan Xiong
Chuan Xiong

Szechuan lovage rhizome

Dosage: 6 - 10g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium
Parts Used Rhizome (根茎 gēn jīng)
Role in Suan Zao Ren Tang

Invigorates Blood and moves Qi to regulate the Liver. Its acrid and dispersing nature balances the sour and astringent quality of Suan Zao Ren, ensuring that Blood is nourished without becoming stagnant. This pairing of sour-collecting with acrid-dispersing is the formula's key synergy for regulating the Liver.

Gan Cao
Gan Cao

Licorice root

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Suan Zao Ren Tang

Harmonizes the other herbs and moderates the acrid dispersal of Chuan Xiong. Its sweet flavour relaxes tension, supplements the middle, and protects the Spleen from the cold nature of Zhi Mu.

Modern Research (5 studies)

  • RCT: Suan Zao Ren Tang for Sleep Disturbance during Methadone Maintenance (2015)
  • Systematic Review & Meta-Analysis: Suanzaoren Formulae for Insomnia (2018)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

In the evening, ideally 1 to 2 hours before bedtime. The classical instruction is to divide into three warm doses throughout the day, but modern clinical practice often concentrates the dose in the evening for insomnia.

Typical Duration

Typically prescribed for 2 to 4 weeks initially, then reassessed. Chronic or recurrent insomnia may require 4 to 8 weeks or longer with periodic practitioner review.

Dietary Advice

Avoid stimulating foods and beverages that may worsen insomnia or generate internal Heat, including coffee, strong tea, alcohol, and spicy or heavily fried foods, particularly in the evening. Favor calming, Blood-nourishing foods such as red dates (jujubes), longan fruit, lotus seeds, lily bulbs, millet porridge, and warm milk. Light, easily digestible evening meals support the formula's action. Avoid eating large meals close to bedtime, as food stagnation in the Stomach can itself disturb sleep.

Modern Usage

Suan Zao Ren Tang is a TCM formula developed by the esteemed ancient physician Hua Tuo during the Eastern Han Dynasty (circa 200 AD). The primary herb, Suan Zao Ren, is one of five herbs in this formula that work synergistically to nourish the Blood and Yin.

It is renowned for its calming and nourishing properties. In TCM, this formula nourishes Heart Blood and Liver Blood, calms the spirit, clears Heat, and nourishes Yin. Practitioners often recommend it for conditions such as restless sleep, anxiety, night sweats, forgetfulness, and other symptoms related to blood and yin deficiency.

Special Populations

Pregnancy

Generally considered safe in pregnancy at standard doses, but should be used with professional guidance. Chuan Xiong (Ligusticum) is a Blood-moving herb that, while used in small doses in obstetric formulas, warrants caution in early pregnancy or in women with a history of miscarriage. Zhi Mu (Anemarrhena) is cold in nature and could potentially affect digestion in pregnant women with weak Spleen Qi. The formula overall is mild and nourishing, but any use during pregnancy should be supervised by a qualified practitioner.

Breastfeeding

Generally considered compatible with breastfeeding. The herbs in this formula are mild and nourishing. One clinical study specifically noted that Suan Zao Ren Tang was used in postpartum depression with results comparable to paroxetine but without notable adverse effects, suggesting suitability for breastfeeding mothers. Chuan Xiong and Zhi Mu are present in modest doses and are not known to have concerning transfer through breast milk. However, as with all herbal medicines during lactation, professional supervision is recommended.

Pediatric Use

Suan Zao Ren Tang can be used in children, but with appropriate dose reduction. A common guideline is roughly one-third of the adult dose for children aged 6 to 12, and one-quarter or less for children under 6, though exact dosing should be determined by a qualified practitioner based on the child's weight and constitution. The formula is mild and nourishing, making it generally well-tolerated. It may be considered for children with nighttime restlessness, difficulty falling asleep, or night terrors when the pattern matches Blood deficiency with restless spirit. The bitter taste of Zhi Mu may make compliance difficult in young children; honey or small amounts of sweetener may be added to improve palatability.

Drug Interactions

Sedative and hypnotic medications (benzodiazepines, zolpidem, etc.): Suan Zao Ren Tang has demonstrated sedative-hypnotic effects mediated through GABA and serotonin receptor pathways. When combined with pharmaceutical sedatives, there may be additive central nervous system depression. Clinical trials have safely combined SZRT with low-dose lorazepam, but patients should be monitored for excessive drowsiness.

Anticoagulant and antiplatelet drugs (warfarin, aspirin, clopidogrel): Chuan Xiong (Ligusticum) has blood-activating properties and may have mild antiplatelet effects. Concurrent use with anticoagulants warrants monitoring of bleeding parameters.

Antidepressants, especially SSRIs and SNRIs: Given that Suan Zao Ren constituents interact with serotonin receptors, theoretical additive serotonergic effects may occur. While clinical interactions have not been well documented, caution is prudent, and patients should inform their prescribing physician.

Gan Cao (Licorice) considerations: Gan Cao is present in a small dose (3g) in this formula. At this level, significant interactions are unlikely, but prolonged use alongside corticosteroids, diuretics, or cardiac glycosides (digoxin) should still be monitored for potential effects on potassium and sodium balance.

Contraindications

Caution

Insomnia caused by excess Heat or Phlegm-Fire harassing the Heart. This formula is designed for deficiency-type insomnia and would not address excess patterns adequately.

Caution

Insomnia due to food stagnation or Stomach disharmony (the classical 'wei bu he ze wo bu an' pattern). Different pathomechanism requires different treatment.

Caution

Patients with Spleen deficiency and loose stools should use with caution. Zhi Mu (Anemarrhena) is cold and slippery in nature, which can aggravate diarrhea.

Caution

Individuals with significant blood stasis patterns. While Chuan Xiong moves Blood, this formula is fundamentally a tonifying prescription and is not designed for stasis-dominant presentations.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Treasure of the East

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