Herb

Gui Zhi

Cinnamon twig | 桂枝

Also known as:

Cinnamon Twig

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Herb

Traditional Chinese Medicine background and properties

Herb Description

Cinnamon twig is one of the most frequently used herbs in classical Chinese medicine, prized for its gentle warming action. It helps the body fight off colds and flu, relieves joint and menstrual pain caused by cold, supports healthy fluid metabolism, and promotes circulation. It is the lead herb in Gui Zhi Tang, historically called the "chief of all formulas."

Herb Category

Main Actions

  • Releases the Muscle Layer
  • Warms the Channels and Disperses Cold
  • Warms Yang and Transforms Qi
  • Subdues Rushing Qi (Ben Tun)
  • Warms Yang in the chest
  • Invigorates Blood and Dispels Stasis

How These Actions Work

'Releases the exterior and resolves the muscle layer' (发汗解肌) means Gui Zhi gently opens the body's surface to expel Wind-Cold pathogens. Unlike Ma Huang (Ephedra), which forcefully induces sweating, Gui Zhi has a milder action. It works by warming the defensive Qi (Wei Qi) and harmonizing it with the nutritive Qi (Ying Qi), making it suitable both when someone is sweating and when they are not. This is why it is the lead herb in Gui Zhi Tang for colds with spontaneous sweating and chills.

'Warms and unblocks the channels and collaterals' (温通经脉) refers to Gui Zhi's ability to promote circulation through the body's pathways by using its warm, pungent nature to disperse Cold obstruction. This makes it valuable for joint pain caused by Cold and Dampness (as in rheumatic conditions), for menstrual pain and irregular periods caused by Cold stagnating in the Blood, and for chest pain from obstruction of Heart Yang (chest Bi pattern).

'Assists Yang and promotes Qi transformation' (助阳化气) means Gui Zhi supports the body's warming, activating functions, particularly the Bladder's ability to properly process and distribute fluids. When Cold blocks Yang Qi, fluids accumulate as edema, difficult urination, or Phlegm-fluid retention. Gui Zhi restores the warmth needed for proper fluid metabolism, which is why it appears in Wu Ling San (Five-Ingredient Powder with Poria) for water retention.

'Calms surging Qi and directs it downward' (平冲降气) addresses a condition called Ben Tun (running piglet) where a person feels a strong surge of Qi rushing upward from the lower abdomen toward the chest and throat, causing panic and distress. Gui Zhi warms Heart Yang and settles this abnormal upward movement of Cold Qi from below.

Patterns Addressed

In TCM, symptoms cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Gui Zhi is traditionally associated with these specific patterns.

The following describes this herb's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Gui Zhi addresses this pattern

Gui Zhi is acrid, sweet, and warm, entering the Lung and Bladder channels. Its acrid warmth disperses Wind-Cold from the body's surface, while its sweet warmth supports the defensive Qi (Wei Qi) and harmonizes it with the nutritive Qi (Ying Qi). Unlike stronger diaphoretics, Gui Zhi gently 'resolves the muscle layer' rather than forcing open the pores, making it uniquely suited for exterior patterns where the person is already sweating (the 'exterior deficiency' type of Wind-Cold invasion). When paired with Bai Shao (White Peony), it achieves the classical principle of harmonizing Ying and Wei.

A practitioner would look for one or more of these signs

Chills

Chills with aversion to wind

Fever

Mild fever

Headaches

Headache from Wind-Cold

Excessive Sweating

Spontaneous sweating that does not relieve the condition

Nasal Congestion

Nasal congestion with clear discharge

TCM Properties

Temperature

Warm

Taste

Acrid / Pungent (辛 xīn), Sweet (甘 gān)

Channels Entered
Heart Lungs Urinary Bladder
Parts Used

Twig (枝 zhī)

This is partial information on the herb's TCM properties. More detailed information is available on the herb's dedicated page

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Botanical & Sourcing

Quality Indicators

Good quality Gui Zhi comes from young, thin twigs (diameter 0.5 cm or less for top grade). The outer surface should be reddish-brown, and the cross-section should show a reddish-brown bark layer and pale yellowish-brown wood. It should have a strong, distinctive cinnamon-like aromatic fragrance and taste sweet with a noticeable pungency, the flavour being strongest in the bark portion. The pieces should be relatively intact with a breakage rate below 10%. Avoid twigs that are thick and woody (over 1.5 cm diameter), dark or blackened in the wood section, weak in aroma, or that show signs of mould or deterioration. Leaf stalks (petioles) mixed in are considered an adulterant under Chinese Pharmacopoeia standards and should not exceed 3% of the material.

Primary Growing Regions

Gui Zhi belongs to the 'Southern herbs' (Nan Yao) category of dao di yao cai. It is primarily produced in Guangxi, Guangdong, and Yunnan provinces of southern China. Guangxi is the largest production region, particularly around Yulin, Fangchenggang, Qinzhou, and Bobai. Guangdong production centres include Luoding (known as the 'Chinese Cinnamon Capital'), Xinyi, and Yunan. Historically, the finest quality cassia was associated with the Lingnan (Two Guangs) region. Vietnamese-origin large-leaf Qinghua cinnamon (Cinnamomum loureiroi) has been considered particularly high in essential oil content, and has been introduced into Chinese cultivation.

Harvesting Season

Spring and summer, primarily in spring around March to May before the tree produces new growth. Branches are also collected during autumn trimming.

Supplier Information

Treasure of the East

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Usage & Safety

How to use this herb and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This herb is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Traditional Dosage Reference

Standard

3–9g

Maximum

Up to 15g for severe Cold-Damp joint pain or strong Cold patterns, under practitioner supervision. Standard clinical use rarely exceeds 9g.

Notes

For releasing the exterior in Wind-Cold patterns, 6 to 9g is typical. For warming the channels and relieving joint pain in Cold-Damp impediment conditions, larger doses of 9 to 15g may be used. For assisting Yang transformation of Qi and promoting water metabolism (as in Wu Ling San), moderate doses of 6 to 9g are standard. When used primarily to warm Heart Yang or calm rushing Qi (Ben Tun), 9g is common. Lower doses (3 to 6g) may be appropriate for patients with mild Cold or as a channel-guiding component in formulas. Excessive dosage in patients with underlying Yin deficiency can cause sweating, dry mouth, thirst, and agitation.

Processing Methods

Processing method

Stir-fried with honey until the surface becomes slightly glossy and non-sticky.

How it changes properties

Honey processing reduces the acrid, dispersing quality and enhances the sweet, tonifying quality. The processed form shifts from surface-releasing toward warming and tonifying the Middle Jiao (digestive system). Its Yang-supporting action is strengthened while its exterior-releasing action is weakened.

When to use this form

When the goal is to tonify Middle Jiao Yang and warm the digestive system rather than release the exterior. Preferred in formulas targeting Spleen Yang deficiency or when the acrid dispersing action is not desired.

Toxicity Classification

Non-toxic

Gui Zhi is classified as non-toxic in the Chinese Pharmacopoeia. The Ben Jing Feng Yuan describes it as 'acrid, sweet, slightly warm, and non-toxic.' Cinnamaldehyde, the primary volatile oil constituent, is generally safe at standard decoction doses. However, the parent plant Cinnamomum cassia contains coumarin, which at high chronic doses can cause hepatotoxicity through biotransformation into reactive metabolites in the liver. This concern is more relevant to concentrated cassia bark products (Rou Gui, cinnamon powder supplements) than to Gui Zhi twigs, which have lower essential oil content. At standard decoction dosages (3 to 9g), Gui Zhi poses no significant toxicity risk. Overdose may cause symptoms related to its warm, acrid nature: excessive sweating, thirst, dry mouth, and in Yin-deficient constitutions, agitation or worsening of Heat signs.

Contraindications

Avoid

Warm-febrile diseases (Wen Bing) and conditions with Heat signs. Gui Zhi is warm and acrid, and will worsen any pattern where pathogenic Heat is already present, whether at the exterior or interior level.

Avoid

Yin deficiency with vigorous Fire (Yin Xu Huo Wang). The warming, dispersing nature of Gui Zhi can further damage Yin fluids and intensify deficiency Heat, worsening symptoms like night sweats, hot flashes, and dry mouth.

Avoid

Blood Heat with bleeding (blood Heat patterns causing hematemesis, epistaxis, or other hemorrhage). As classical texts warn, Gui Zhi's warmth can 'move Blood' recklessly, aggravating bleeding conditions. The Ben Cao Cong Xin states: 'For Yin-deficient persons, in all Blood conditions, it must not be mistakenly used.'

Caution

Pregnancy. Gui Zhi's warm, acrid, and Blood-moving properties may disturb the fetus. Classical sources list it among herbs to be used with caution during pregnancy. While Gui ZhiFu Ling Wan is a classical formula used in specific pregnancy-related Blood stasis conditions, this requires expert prescription and is not a general-use scenario.

Caution

Excessive menstrual bleeding (menorrhagia). Gui Zhi's warming and Blood-moving properties may worsen heavy menstrual flow in the absence of Cold stasis.

Caution

Interior excess Heat with exterior symptoms. When an exterior pattern is accompanied by strong interior Heat, Gui Zhi's warmth may trap Heat inside. Cooling, exterior-releasing herbs are more appropriate in such cases.

Classical Incompatibilities

Gui Zhi itself does not appear directly on the Eighteen Incompatibilities or Nineteen Mutual Fears lists. The related substance Guan Gui (官桂, a form of Rou Gui/cinnamon bark) is listed in the Nineteen Mutual Fears as fearing Chi Shi Zhi (Halloysitum Rubrum). However, the 2020 edition of the Chinese Pharmacopoeia clarifies that Gui Zhi and Chi Shi Zhi are not considered incompatible and may be used together. This distinction arises because Gui Zhi (the twig) and Rou Gui (the bark) are recognized as separate medicinal substances despite coming from the same plant.

Special Populations

Pregnancy

Use with caution during pregnancy. Gui Zhi is warm, acrid, and has Blood-moving properties that may stimulate uterine activity or disturb the fetus. Classical texts list it among herbs that are cautioned against during pregnancy (妊娠慎用). Research has shown that the essential oil from Cinnamomum cassia twigs can inhibit oxytocin-induced uterine contractions in vitro, but its warming, dispersing nature still poses theoretical risk. While the classical formula Gui Zhi Fu Ling Wan is used for specific pregnancy complications involving Blood stasis (under expert supervision), Gui Zhi should not be used casually during pregnancy. Avoid unless prescribed by an experienced practitioner for a specific condition.

Breastfeeding

No specific classical or modern prohibitions exist for Gui Zhi during breastfeeding. However, its warm, acrid, and dispersing properties mean it should be used cautiously and at conservative doses in nursing mothers. Cinnamaldehyde and other volatile oil components may pass into breast milk in small amounts. One historical Western herbal source describes cassia as potentially capable of decreasing milk secretion. It is best used only when clinically indicated for a specific Cold pattern, and not as a routine tonic during lactation.

Pediatric Use

Gui Zhi can be used in children for appropriate Cold-pattern conditions such as Wind-Cold common cold, but dosage should be reduced proportionally based on age and body weight. As a general guide, children under 6 may use roughly one-third of the adult dose, and children 6 to 12 may use one-half. Because of its warm, dispersing nature, it should be used carefully in children who tend to run hot or who have Yin-deficient constitutions. Avoid prolonged use. Paediatric prescriptions should always be supervised by a qualified practitioner.

Drug Interactions

Anticoagulant and antiplatelet medications (e.g. warfarin, aspirin): Cinnamaldehyde and cinnamic acid from Cinnamomum cassia have blood-thinning properties. Concurrent use with anticoagulants may theoretically potentiate bleeding risk. Patients on such medications should inform their healthcare provider before using Gui Zhi-containing formulas.

Diabetes medications (insulin, metformin, sulfonylureas): Cinnamomum cassia has demonstrated blood glucose-lowering effects in multiple studies. Combined use with conventional diabetes drugs may enhance hypoglycaemic effects, requiring closer blood sugar monitoring.

CYP3A4-metabolised drugs: Research has shown that cinnamon can inhibit CYP3A4 enzyme activity, which may increase plasma levels of drugs metabolised by this pathway (e.g. pioglitazone, certain statins, some calcium channel blockers). Clinical significance at standard decoction doses is uncertain but warrants awareness.

Hepatotoxic drugs: Coumarin present in Cinnamomum cassia (more concentrated in bark than twigs) undergoes hepatic metabolism that can produce reactive metabolites. Concurrent use with other hepatotoxic drugs may theoretically increase liver burden, though this is more relevant to concentrated cassia bark supplements than standard Gui Zhi decoctions.

Dietary Advice

While taking Gui Zhi formulas for exterior Wind-Cold conditions, avoid cold, raw, and greasy foods, which impede the sweating response and the dispersal of Cold. Classical instructions for Gui Zhi Tang specifically recommend consuming hot rice porridge (xi zhou) after taking the formula to support the stomach and assist gentle sweating. Avoid sour, astringent foods that may obstruct the exterior-releasing action. When Gui Zhi is used for warming the interior or assisting Yang, avoid excessive cold drinks and iced foods. Those with any underlying Heat tendency should avoid spicy, rich, and warming foods that could compound excess warmth.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.