Herb

Di Long

Earthworms | 地龙

Also known as:

Qiu Yin (蚯蚓)

Parts Used

Animal — whole (全虫 quán chóng)

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Herb

Traditional Chinese Medicine background and properties

Herb Description

Di Long (earthworm) is a classic animal-derived medicine used in Chinese medicine to address conditions involving blocked circulation, high fevers with seizures, wheezing from lung heat, and swelling with reduced urination. It is best known for its ability to open the body's network vessels, making it a key ingredient in formulas for stroke recovery and joint pain. Despite its unusual origin, it has a long history of safe use spanning over two thousand years.

Herb Category

Main Actions

  • Settles Fright and Calms Convulsions
  • Calms the Liver and Extinguishes Wind
  • Unblocks the Channels and Collaterals
  • Calms Wheezing
  • Promotes Urination

How These Actions Work

'Clears Heat and arrests convulsions' means Di Long can bring down high fevers and stop seizures or spasms triggered by excessive Heat. Its cold, salty nature makes it especially suited for acute febrile illnesses where Heat has stirred up internal Wind, causing delirium, convulsions, or loss of consciousness. This is one of its most classical uses, recorded since the Shen Nong Ben Cao Jing.

'Extinguishes Wind and calms the Liver' refers to Di Long's ability to settle internal Wind patterns associated with the Liver, such as headaches, dizziness, or tremors caused by Liver Yang rising. Its salty taste softens and descends, helping to anchor rising Yang and settle agitated movement in the body.

'Unblocks the channels and collaterals' is Di Long's most widely used action in modern practice. As an animal substance, Di Long has a penetrating, burrowing nature that allows it to reach deep into the body's network vessels (collaterals). This makes it highly valued for conditions where blockage in the channels causes paralysis, numbness, joint pain, or restricted movement, such as post-stroke hemiplegia or chronic joint pain (Bi syndrome).

'Calms wheezing' means Di Long can relax the airways and ease breathing difficulty. This applies specifically to wheezing and asthma caused by Lung Heat. Its cold nature clears Heat from the Lungs while its channel-opening properties help relieve bronchial constriction. The active compound succinic acid is considered the main component responsible for this effect.

'Promotes urination' means Di Long can help the body expel excess fluid through the urinary system. This is used in cases of edema with scanty urine, particularly when Heat is involved. It enters the Urinary Bladder channel, directly supporting this function.

Patterns Addressed

In TCM, symptoms cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Di Long is traditionally associated with these specific patterns.

The following describes this herb's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Di Long addresses this pattern

Di Long's cold, salty nature and its strong affinity for the Liver channel make it well suited for Wind-Stroke affecting the channels and collaterals. In this pattern, Wind (often combined with Blood stasis or Qi deficiency) obstructs the network vessels, leading to hemiplegia, numbness, and impaired speech. Di Long's outstanding ability to penetrate and unblock the collaterals directly addresses this obstruction. Its burrowing, mobile nature (described classically as 'good at crawling through passages') enables it to guide other medicines through the entire body's network vessels, restoring circulation to paralyzed limbs. This is the action showcased in Bǔ Yáng Huán Wǔ Tāng.

A practitioner would look for one or more of these signs

Hemiplegia After Cerebrovascular Accident

One-sided paralysis after stroke

Numbness of the Limbs

Numbness or tingling in the extremities

Slurred Speech

Difficulty speaking clearly

Facial Paralysis

Deviation of mouth and eye

TCM Properties

Temperature

Cold

Taste

Salty (咸 xián)

Channels Entered
Liver Spleen Urinary Bladder Lungs
Parts Used

Animal — whole (全虫 quán chóng)

This is partial information on the herb's TCM properties. More detailed information is available on the herb's dedicated page

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Botanical & Sourcing

Quality Indicators

Guang Di Long (the premium grade): Dried pieces should be long (15-20 cm), flat and strip-shaped with slightly curled edges, about 1-2 cm wide. The dorsal surface is brownish-brown to purplish-grey, the ventral surface light yellowish-brown. The clitellum ("white collar") at segments 14-16 should be clearly visible and slightly glossy. Good specimens are light in weight, slightly leathery in texture, and difficult to break. They should have a characteristic fishy smell and a slightly salty taste. Prefer pieces that are large, plump, intact (not broken), and free of internal soil or mud residue. Avoid specimens that are excessively dark, moldy, insect-damaged, or still containing visible soil.

Primary Growing Regions

Guang Di Long (广地龙, P. aspergillum) is considered the superior grade and is a recognized "Guang Yao" (广药, Guangdong medicinal). Its primary producing regions are Guangdong province (especially Boluo, Heshan, Nanhai, Panyu, Xinhui, Shunde, Jiangmen, Gaozhou, Huidong, Heyuan, and Xingning counties), Guangxi province (Rongxian, Hengxian, Lingshan, Beihai, Wuzhou, Beiliu), and Hainan and Fujian provinces. Hu Di Long (沪地龙, the other three species) is mainly produced in Shanghai, Zhejiang, Jiangsu, as well as Shandong, Henan, Anhui, and Fujian provinces. Guang Di Long from Guangdong and Guangxi is the most prized variety and is listed among Guangdong's "Ten Great Southern Medicines" (十大南药).

Harvesting Season

Guang Di Long: spring through autumn. Hu Di Long: summer.

Supplier Information

Treasure of the East

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Miscellaneous Info

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Usage & Safety

How to use this herb and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This herb is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Traditional Dosage Reference

Standard

5-15g

Maximum

Up to 15-20g in decoction for severe conditions (acute stroke sequelae, severe asthma). When using fresh earthworms, up to 10-20g is used. As dry powder for oral ingestion, 1-2g per dose, up to 3-4g per dose in severe cases.

Notes

Lower doses (5-10g) are used for general Heat-clearing, relieving wheezing, and promoting urination. Higher doses (10-15g) are used for unblocking collaterals in stroke sequelae and stubborn joint pain. When taken as dried powder (ground and swallowed rather than decocted), the dose is much smaller: 1-2g per dose. Fresh Di Long is used at roughly double the dried decoction dose. Wine-processed Di Long (酒制地龙) enhances the Blood-activating and collateral-unblocking action and reduces the strong fishy odor. Note that boiling or high-temperature processing destroys some of the fibrinolytic enzyme (lumbrokinase) activity, so powder form may preserve more of the thrombolytic effect.

Processing Methods

Processing method

The cleaned, cut segments of Di Long are mixed evenly with yellow rice wine (huang jiu), briefly moistened until the wine is absorbed, then stir-fried over low heat until the surface turns brown. The standard ratio is 12.5 kg of rice wine per 100 kg of Di Long.

How it changes properties

Wine processing moderates Di Long's intensely cold and salty nature, making it less likely to injure the Spleen and Stomach. It also removes the strong fishy smell, making the herb easier to take. Most importantly, wine enhances Di Long's channel-unblocking and Blood-moving actions, because wine itself has a warm, dispersing nature that directs herbs into the channels and collaterals. Research shows that wine-processed Di Long is superior to raw Di Long for reducing blood viscosity and dissolving blood clots.

When to use this form

Preferred for Wind-Damp Bi syndrome with joint pain and channel obstruction, and for post-stroke paralysis. Whenever the treatment priority is unblocking collaterals and moving Blood rather than clearing Heat, the wine-processed form is the better choice. Also preferred for patients with weaker digestion who cannot tolerate the raw form's strong fishy taste and cold nature.

Toxicity Classification

Non-toxic

Di Long is classified as non-toxic in the Ben Cao Gang Mu and modern Chinese Pharmacopoeia, though the original Shen Nong Ben Cao Jing listed it in the lower grade (implying caution). The earthworm body contains lumbrilysin (蚯蚓毒素), a hemolytic component, and lumbrofebin (蚯蚓解热碱), an antipyretic alkaloid. In processed dried form at standard dosages, these compounds do not cause significant toxicity. Overdosage may cause gastrointestinal discomfort (nausea, abdominal pain). Allergic reactions are the main safety concern: skin rash, itching, and in rare cases with injectable preparations, anaphylaxis-like symptoms (pallor, sweating, difficulty breathing, blood pressure drop). Raw, unprocessed earthworms may carry parasites or bacteria and should never be used internally without proper preparation.

Contraindications

Avoid

Pregnancy: Di Long has channel-unblocking and Blood-moving properties that may disturb the fetus and potentially stimulate uterine contractions. Classical sources list it as contraindicated (禁用) in pregnancy.

Caution

Spleen and Stomach deficiency-cold: Di Long is cold in nature and can injure Spleen and Stomach Yang. People with chronic loose stools, poor appetite, or cold abdomen should avoid it.

Caution

No true Heat pattern present: As a cold-natured substance, Di Long should not be used for convulsions, wheezing, or joint pain that are not caused by Heat or Heat-toxin.

Caution

Active bleeding or bleeding disorders: Due to its fibrinolytic and anticoagulant properties (via lumbrokinase), Di Long may increase bleeding risk in people with hemorrhagic conditions.

Avoid

Known allergy to earthworm proteins: Allergic reactions including skin rash, itching, and in rare cases anaphylaxis-like symptoms have been reported, particularly with injectable preparations.

Special Populations

Pregnancy

Contraindicated in pregnancy. Di Long has strong channel-unblocking and collateral-penetrating properties. Classical sources (including the Chinese Pharmacopoeia notes) explicitly prohibit its use during pregnancy (孕妇禁服), citing the risk of disturbing the fetus (动胎). Research has also suggested potential teratogenic effects. There are no circumstances under which Di Long should be used during pregnancy without urgent medical justification.

Breastfeeding

There is limited specific data on Di Long during breastfeeding. Given its cold nature and bioactive protein content (including lumbrokinase and lumbrilysin), there is a theoretical risk of these components transferring through breast milk or of the cold nature affecting the nursing infant's digestion. Caution is advised, and it is generally not recommended during breastfeeding unless the clinical benefit clearly outweighs potential risks, under practitioner supervision.

Pediatric Use

Di Long can be used in children for high fever with convulsions (acute childhood fright wind) at reduced, age-appropriate doses, typically one-third to one-half of the adult dose depending on the child's age and weight. It has a long history of pediatric use for febrile seizures. However, highly allergic children require extra caution. The strong fishy taste may cause nausea or vomiting in children, so powder form mixed with other herbs or encapsulated preparations may be better tolerated than decoction.

Drug Interactions

Anticoagulant and antiplatelet drugs (warfarin, heparin, aspirin, clopidogrel, DOACs): Di Long contains lumbrokinase and other fibrinolytic proteins with demonstrated anticoagulant and thrombolytic activity. Concurrent use with pharmaceutical anticoagulants or antiplatelets may have an additive blood-thinning effect and increase bleeding risk. Regular monitoring of coagulation parameters (INR, PT) is advised if co-administration is necessary.

Thrombolytic agents (alteplase, tenecteplase): Theoretical additive fibrinolytic effect. Concurrent use should be avoided or closely monitored.

Antihypertensive drugs: Di Long has demonstrated hypotensive effects in animal studies and clinical use. Combined use with antihypertensive medications may potentiate blood pressure lowering, requiring dose adjustment and monitoring.

Dietary Advice

Because Di Long is cold in nature, it is best to avoid excessively cold or raw foods while taking it, especially for individuals with weaker digestion. Warm, easily digestible foods help counterbalance its cold property. Avoid alcohol in excess unless the practitioner specifically prescribes wine-processed Di Long. If taking Di Long for its blood-moving properties, reducing intake of greasy, fatty foods may support therapeutic outcomes.

Cautions & Warnings

Although this herb is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.