Formula

Da Huang Mu Dan Pi Tang

大黄牡丹皮汤

Also known as:

Da Huang Mu Dan Tang (大黄牡丹汤) , Gua Zi Tang (瓜子汤)

Properties

Purgative formulas · Cold

Key Ingredients

Da Huang, Tao Ren

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Select Product Type

Select Supplier

Select Size

Quantity

$52.00 ($0.52/g)
Made to order · Non-cancellable once ordered · Policy
For shipments to: United States Change
Standard Shipping (3-5 business days): $4.99
Express Shipping (1-2 business days): $9.99
Free shipping on orders over $75

About This Formula*

Traditional Chinese Medicine background and properties

Formula Description*

A classical formula used to treat intestinal abscesses (similar to acute appendicitis) and lower abdominal infections caused by a buildup of heat, dampness, and blood stagnation. It works by purging heat downward through the bowels, breaking up blood stasis, and reducing swelling and inflammation in the lower abdomen.

Formula Category*

Main Actions*

  • Clears Heat from Blood Stasis
  • Purges Heat and Unblocks the Bowels
  • Disperses Swelling and Dissipates Nodules
  • Expels pus and resolves intestinal abscess
  • Clears Damp-Heat from the intestines

TCM Patterns*

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Da Huang Mu Dan Pi Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Da Huang Mu Dan Pi Tang addresses this pattern

When damp-heat accumulates in the Large Intestine, it obstructs the flow of Qi and Blood in the intestinal network vessels. The heat scorches and congests the blood locally, while dampness creates a turbid environment that breeds toxic material. Together, these pathogenic factors cause the tissue to swell, become painful, and eventually form an abscess. Da Huang and Mang Xiao powerfully purge the accumulated damp-heat downward through the bowels, while Dong Gua Ren specifically drains dampness and clears turbid pus from the intestines. The blood-moving herbs (Tao Ren, Mu Dan Pi) ensure that the blood stagnation secondary to the damp-heat obstruction is also resolved, preventing the abscess from worsening.

A practitioner would look for one or more of these signs

Abdominal Pain

Right lower abdominal pain that worsens with pressure (rebound tenderness)

Fever

Intermittent fever with spontaneous sweating and chills

Constipation

Constipation or difficult bowel movements

Abdominal Distention

Palpable swelling or fullness in the lower right abdomen

Yellow Tongue Coating

Yellow, greasy tongue coating indicating damp-heat

How It Addresses the Root Cause*

This formula addresses a condition the classical texts call chang yong (肠痈, intestinal abscess), which corresponds closely to acute appendicitis in modern terms. The underlying disease mechanism involves Damp-Heat accumulating in the intestines. When this pathogenic Damp-Heat becomes trapped and cannot be dispersed, it causes the local Qi and Blood to congeal and stagnate. The combination of Heat, Dampness, and Blood stasis clumped together in the lower right abdomen creates a toxic environment where the flesh begins to rot and pus may form.

Because Heat is bound in the interior, there is pain that worsens with pressure. The right leg may be drawn up and unable to straighten (classically called "contracted-foot intestinal abscess"). Since the disease is in the intestines and does not involve the Bladder, urination remains normal, which is an important distinguishing sign. Meanwhile, the struggle between the body's defensive forces and the pathogenic factors causes intermittent fever, spontaneous sweating, and alternating chills. The yellow greasy tongue coating and slippery, rapid pulse confirm that this is an excess-type pattern of Damp-Heat congealing with Blood stasis in the bowels.

The treatment strategy is straightforward: purge the accumulated Heat downward through the bowels, break up the Blood stasis, and disperse the swelling before the abscess progresses to full suppuration. The formula works by giving the trapped pathogenic material an exit route, draining it downward and out of the body.

Formula Properties*

Temperature

Cold

Taste Profile

Predominantly bitter and salty, with sweet undertones from Dong Gua Zi — bitter to drain Heat and purge, salty to soften hardness and guide downward, sweet to clear Dampness and expel pus.

Target Organs
Large Intestine Stomach
Channels Entered
Large Intestine Stomach Liver

Formula Origin

Jin Gui Yao Lue (金匮要略) by Zhang Zhongjing

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

Quantity Description

Loading quantity information...

Concentration Ratio

Loading concentration information...

Fabrication Method

Loading fabrication information...

Supplier Certifications

Loading certifications information...

Supplier Information

Treasure of the East

Loading supplier information...

Loading supplier attributes...

Miscellaneous Info

No additional information available

Ingredients in Da Huang Mu Dan Pi Tang

Detailed information about each herb in Da Huang Mu Dan Pi Tang and their roles

Kings
Deputies
Assistants
Da Huang
Da Huang

Rhubarb root and rhizome

Dosage: 9 - 12g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Spleen, Stomach, Large Intestine, Liver, Pericardium
Parts Used Root (根 gēn)
Role in Da Huang Mu Dan Pi Tang

Purges intestinal heat and accumulated toxins downward through the bowels, while also entering the Blood level to dispel blood stasis. As the primary purgative, it addresses both the heat obstruction and the stagnant blood that form the core of the intestinal abscess pathomechanism.

Tao Ren
Tao Ren

Peach kernel

Dosage: 9 - 12g

Temperature Neutral
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Heart, Liver, Large Intestine
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Da Huang Mu Dan Pi Tang

Powerfully breaks up blood stasis and disperses abscesses. Working alongside Da Huang, it targets the blood stagnation that is central to abscess formation, while also gently moistening the intestines to support downward elimination.

Mang Xiao
Mang Xiao

Mirabilite

Dosage: 6 - 9g

Temperature Cold
Taste Bitter (苦 kǔ), Salty (咸 xián)
Organ Affinity Stomach, Large Intestine
Parts Used Mineral (矿物 kuàng wù)
Role in Da Huang Mu Dan Pi Tang

Softens hardness and disperses knotted accumulations with its salty, cold nature. It reinforces Da Huang's purgative and heat-clearing action, helping to break down the firm, swollen mass in the intestines.

Mu Dan Pi
Mu Dan Pi

Tree peony root bark

Dosage: 3 - 9g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Heart, Liver, Kidneys
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Da Huang Mu Dan Pi Tang

Cools the Blood and disperses blood stasis, while clearing heat from the Blood level. It complements the King herbs by addressing the heat-driven blood stagnation that generates the abscess, and helps resolve residual inflammation.

Dong Gua Zi
Dong Gua Zi

Winter melon seed

Dosage: 15 - 30g

Temperature Cool
Taste Sweet (甘 gān)
Organ Affinity Lungs, Large Intestine, Stomach, Small Intestine
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Da Huang Mu Dan Pi Tang

Clears intestinal heat, promotes the drainage of dampness, and expels pus. As the sole herb specifically indicated for abscess drainage, it ensures that accumulated pus and turbid fluids are discharged, preventing further tissue damage.

Modern Research (2 studies)

  • Efficacy and Adverse Reactions of Dahuang Mudan Decoction Combined with Laparoscopy in the Treatment of Appendicitis: A Meta-Analysis (2023)
  • Anti-sepsis effects of Dahuang Mudan decoction and its disassembled prescriptions (Preclinical study, 2024)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

Loading storage and consumption information...

Best Time to Take

On an empty stomach, typically 30-60 minutes before meals or between meals, to maximize the purgative effect and allow the formula to act directly on the intestines without interference from food.

Typical Duration

Acute use only: typically 3-7 days maximum, reassessed daily. The original text instructs taking as a single large dose (顿服). Modern clinical use involves daily doses for a few days, discontinued promptly once symptoms resolve.

Dietary Advice

While taking this formula, avoid cold and raw foods (such as ice water, raw salads, and sashimi) which may counteract the formula's ability to move stagnation by further congealing the bowels. Avoid greasy, fried, and heavy foods that generate more Dampness and Heat in the intestines, worsening the underlying condition. Spicy and pungent foods (chili, alcohol, pepper) should also be avoided as they can inflame the condition further. Favor a light, easily digestible diet. Congee (rice porridge), clear soups, and lightly steamed vegetables are ideal. Winter melon soup is particularly appropriate as it supports the formula's action of clearing Heat and draining Dampness. Adequate hydration is important, especially because the formula's purgative action can lead to fluid loss.

Special Populations

Pregnancy

Contraindicated. This formula should not be used during pregnancy under any circumstances without urgent specialist supervision. It contains multiple herbs that pose serious risks: - Da Huang (Rhubarb): a strong purgative classified as cautionary during pregnancy in the Chinese Pharmacopoeia. Studies indicate that Da Huang's reproductive toxicity dose is as low as 1-3 times the standard clinical dose, posing a tangible risk of uterine stimulation and miscarriage. - Mang Xiao (Mirabilite): another potent purgative that promotes strong downward movement, contraindicated in pregnancy. - Tao Ren (Peach Kernel): a powerful Blood-moving herb with known abortifacient properties. It can stimulate uterine contractions. - Mu Dan Pi (Moutan Bark): an herb that invigorates Blood and has demonstrated anti-early-pregnancy effects in animal studies. The formula's overall design is to drive pathogenic material forcefully downward, which directly threatens fetal stability. The combined purgative and Blood-breaking actions make this one of the most clearly contraindicated formulas in pregnancy.

Breastfeeding

Use with caution during breastfeeding. The primary concerns are: - Da Huang (Rhubarb) contains anthraquinone compounds (such as emodin and sennosides) that are known to pass into breast milk. These can cause diarrhea and intestinal cramping in the nursing infant. - Mang Xiao (Mirabilite, sodium sulfate) has a strong osmotic purgative effect. While systemic absorption is limited, its combined use with Da Huang increases the likelihood of gastrointestinal disturbance being passed to the infant through breast milk. - The formula is designed for short-term acute use, not prolonged administration, which somewhat limits exposure. However, breastfeeding mothers should generally avoid this formula unless the clinical situation is urgent and no safer alternative exists. If the formula must be used, consider temporarily suspending breastfeeding during treatment and for 24-48 hours afterward, and consult both a TCM practitioner and a pediatrician.

Pediatric Use

This formula is generally not recommended for infants or young children. Specific considerations: - Classical sources and modern guidelines specifically list appendicitis in infants as a contraindication for this formula due to the aggressive purgative action, which can cause dangerous fluid and electrolyte loss in small children. - For older children (roughly age 7 and above) with confirmed acute uncomplicated appendicitis presenting with a clear Damp-Heat excess pattern, some modern Chinese clinical reports describe cautious use at significantly reduced dosages (typically one-third to one-half of the adult dose, adjusted by body weight and constitution). - Children are more sensitive to the purgative effects of Da Huang and Mang Xiao. Close monitoring for dehydration, electrolyte imbalance, and excessive diarrhea is essential. - A qualified practitioner experienced in pediatric cases should always supervise use. The formula should be discontinued as soon as symptoms improve.

Cautions & Warnings

Da Huang Mu Dan Pi Tang is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Da Huang Mu Dan Pi Tang.