Herb Whole plant / Aerial parts (全草 quán cǎo)

Liu Ji Nu

Diverse wormwood herb · 刘寄奴

Artemisia anomala S. Moore · Herba Artemisiae Anomalae

Also known as: Jin Ji Nu (金寄奴)

Images shown are for educational purposes only

Liu Ji Nu is a Blood-moving herb uniquely named after an ancient Chinese emperor (Liu Yu, whose childhood name was Ji Nu). It is best known for treating injuries, wounds, and pain caused by stuck or stagnant Blood, including traumatic injuries, postpartum pain, and painful or absent menstrual periods. It also helps with indigestion and food-related abdominal pain.

TCM Properties

Temperature

Warm

Taste

Bitter (苦 kǔ)

Channels entered

Heart, Spleen

Parts used

Whole plant / Aerial parts (全草 quán cǎo)

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What This Herb Does

Every herb has a specific set of actions — here's what Liu Ji Nu does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Liu Ji Nu is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Liu Ji Nu performs to restore balance in the body:

How these actions work

'Breaks up Blood stasis and unblocks menstruation' means Liu Ji Nu has a strong ability to move and break through stagnant Blood. When Blood becomes stuck and stops flowing properly, it can cause severe pain, missed periods, or painful masses in the abdomen. This herb's warm, bitter nature drives it powerfully into the Blood level, dispersing clots and restoring flow. It is used for conditions like absent or painful periods caused by Blood stagnation, and postpartum abdominal pain from retained blood clots (lochia).

'Disperses stasis and alleviates pain' refers to this herb's ability to resolve bruising, swelling, and pain from physical trauma. Whether from falls, fractures, sprains, or battlefield injuries, Liu Ji Nu moves stagnant Blood away from the injured area, reducing swelling and relieving pain. It can be taken internally or applied topically as a powder for this purpose. Classical texts famously describe it as a "key medicine for metal-inflicted wounds" (金疮要药).

'Stops bleeding and reduces swelling' may seem contradictory for a Blood-moving herb, but Liu Ji Nu has the unique property of stopping bleeding precisely by breaking up stasis. As the classical text Ben Cao Qiu Zhen explains: when Blood is stuck, it cannot return to its channels, so bleeding continues. By breaking up the obstruction, the Blood can circulate normally again and the bleeding stops. Externally, the powdered herb is applied directly to wounds, cuts, or burns to stop bleeding and promote healing.

'Reduces food stagnation and transforms accumulations' reflects Liu Ji Nu's aromatic quality, which enlivens the Spleen and Stomach. When food sits undigested in the abdomen causing pain, bloating, or diarrhea, this herb can help move things through. This action is distinctive enough that the herb has earned the folk name "Hua Shi Dan" (化食丹), meaning "pill that dissolves food."

Patterns Addressed

In TCM, symptoms cluster into recognizable patterns of disharmony. Liu Ji Nu is used to help correct these specific patterns.

Why Liu Ji Nu addresses this pattern

Liu Ji Nu directly addresses Blood Stasis through its warm, bitter nature. Bitter descends and drains, while warmth activates Blood circulation. Together these properties allow the herb to powerfully break through stagnant Blood. It enters the Heart channel (the Heart governs Blood) and the Spleen channel (the Spleen holds Blood), giving it a direct pathway to resolve Blood accumulation. This makes it particularly effective when Blood Stasis manifests as traumatic injury pain, postpartum retained lochia, or abdominal masses.

A practitioner would look for one or more of these signs

Amenorrhea

From Blood stasis blocking the uterine vessels

Amenorrhea

Sharp, fixed, stabbing menstrual pain

Abdominal Pain

Fixed location, worse with pressure, from stagnant Blood

Bruising

Dark purple bruises from traumatic injury

Commonly Used For

These are conditions where Liu Ji Nu is frequently used — but only when they arise from the specific patterns it addresses, not in all cases

Arises from: Blood Stasis

TCM Interpretation

In TCM, painful menstruation is most commonly understood as Blood failing to flow smoothly through the uterine vessels. When Blood becomes stagnant in the lower abdomen, it creates a blockage that produces sharp, stabbing pain that is fixed in location and typically worse with pressure. The pain often worsens at the start of the period when the body is trying to push old Blood out against the obstruction. Contributing factors include cold exposure (which congeals Blood), emotional stress (which stagnates Qi, leading to Blood stasis), or physical trauma to the pelvic area.

Why Liu Ji Nu Helps

Liu Ji Nu's warm, bitter nature allows it to powerfully break through stagnant Blood and restore normal circulation. Its warmth counters the congealing effect of cold (a common cause of menstrual pain), while its Blood-moving action directly addresses the underlying blockage. By entering the Heart channel (which governs Blood) and the Spleen channel (which holds Blood in the vessels), it reaches the systems responsible for healthy Blood flow. Classical sources describe it as able to 'break Blood and descend distension,' making it well suited for the congestion and pain of Blood stasis dysmenorrhea.

Also commonly used for

Postpartum Abdominal Pain

From retained lochia or Blood stasis

Sprains

Soft tissue injuries with swelling

Bone Fractures

As adjunct for pain and swelling from fractures

Skin Burns

Applied topically as powder for burn wounds

Wounds

External bleeding from cuts and lacerations

Hepatitis

Particularly infectious hepatitis with jaundice

Hematuria

Blood in urine

Dysentery

Bloody dysentery

Herb Properties

Every herb has an inherent temperature, taste, and affinity for specific channels — these properties determine how it interacts with the body

Temperature

Warm

Taste

Bitter (苦 kǔ)

Channels Entered

Heart Spleen

Parts Used

Whole plant / Aerial parts (全草 quán cǎo)

Dosage & Preparation

These are general dosage guidelines for Liu Ji Nu — always follow your practitioner's recommendation, as dosages vary based on the formula and your individual condition

Standard dosage

3–10g

Maximum dosage

Up to 15g in decoction for acute traumatic injury or severe Blood stasis, under practitioner supervision. External use dosage is as needed.

Dosage notes

Use lower doses (3–6g) for mild Blood stasis, food stagnation, or as part of a multi-herb formula. Use higher doses (6–10g) for acute traumatic injury, severe dysmenorrhea with Blood stasis, or postpartum abdominal pain with retained lochia. For external wound application, the powdered herb is applied directly to the wound in appropriate amounts. When used for its digestive function (food stagnation), moderate doses suffice. The classical caution that excessive dosing causes diarrhea should be respected; doses above the standard range require careful monitoring.

Preparation

No special decoction handling is required. Liu Ji Nu is decocted normally with other herbs. For external use on wounds, the dried herb is ground into a fine powder and applied directly to the wound surface. Historically, the Lei Gong Pao Zhi Lun describes a processing method using only the seeds, wiping the shell clean, then steaming with wine from the si hour to the shen hour (roughly 9 AM to 3 PM) before drying.

Processing Methods

In TCM, the same herb can be prepared in different ways to change its effects — here's how processing alters what Liu Ji Nu does

Processing method

The seeds/fruits are cleaned, mixed with wine, and steamed from the si hour (9 AM) until the shen hour (3 PM), then sun-dried. As described in Lei Gong Pao Zhi Lun.

How it changes properties

Wine-steaming enhances the herb's Blood-moving and channel-unblocking properties. The wine (a warm, pungent substance) synergizes with the herb's warm nature to more powerfully dispel Blood stasis and penetrate the channels. The prolonged steaming moderates some of the herb's harshness.

When to use this form

When the primary goal is to strongly invigorate Blood and unblock the channels for conditions like amenorrhea or deep-seated Blood stasis. The wine-processed form was historically preferred when using the seeds/fruits rather than the whole plant.

Common Herb Pairs

These ingredients are traditionally combined with Liu Ji Nu for enhanced therapeutic effect

Yan Hu Suo
Yan Hu Suo 1:1 (Liu Ji Nu 30g : Yan Hu Suo 30g)

Liu Ji Nu breaks up Blood stasis while Yan Hu Suo powerfully moves Qi and Blood to relieve pain. Together they address both the structural blockage (stagnant Blood) and the resulting pain from Qi obstruction, providing stronger analgesic and stasis-resolving effects than either herb alone.

When to use: Traumatic injuries with internal Blood stasis and significant pain, especially abdominal pain from falls or blows. This is the classical pairing from the Qian Jin Fang.

Gu Sui Bu
Gu Sui Bu 1:1 (Liu Ji Nu 30g : Gu Sui Bu 30g)

Liu Ji Nu disperses stagnant Blood from injured tissue while Gu Sui Bu strengthens the bones, promotes bone healing, and tonifies the Liver and Kidneys. Together they address both the acute Blood stasis from trauma and the underlying structural damage, promoting comprehensive injury recovery.

When to use: Fractures, bone injuries, or severe falls where there is both Blood stasis and bone/tendon damage that needs healing.

Dang Gui
Dang Gui 2:1 (Liu Ji Nu 60g : Dang Gui 30g, as in the classical formula)

Liu Ji Nu breaks up stagnant Blood while Dang Gui nourishes and invigorates Blood. This pairing ensures that Blood stasis is resolved without depleting the body's Blood supply, combining a strong stasis-breaker with a Blood tonic for a balanced approach.

When to use: Postpartum conditions where retained lochia causes abdominal pain, but the new mother is also Blood-deficient from childbirth. The classical Liu Ji Nu Yin from Wei Sheng Jia Bao uses this pairing.

Gan Cao
Gan Cao 1:1 (equal parts)

Liu Ji Nu moves Blood and breaks stasis while Gan Cao moderates its harsh, draining nature and relieves pain. This simple two-herb combination covers postpartum Blood movement disorders by pairing a strong stasis-breaker with a harmonizing, pain-relieving herb.

When to use: Postpartum disorders with Blood stasis causing dizziness, agitation, or general malaise. From the Sheng Ji Zong Lu (Liu Ji Nu Tang) for 'all postpartum Blood disorders.'

Comparable Ingredients

These ingredients have overlapping uses — here's how to tell them apart

Yi Mu Cao
Liu Ji Nu vs Yi Mu Cao

Both herbs invigorate Blood and are used for gynecological Blood stasis conditions like amenorrhea and postpartum pain. However, Yi Mu Cao (Leonurus/motherwort) also promotes urination and reduces edema, making it better for postpartum conditions complicated by swelling or water retention. Liu Ji Nu has stronger trauma-healing and hemostatic (bleeding-stopping) properties and uniquely addresses food stagnation, making it the better choice for physical injuries and when digestive symptoms accompany Blood stasis.

Ze Lan
Liu Ji Nu vs Ze Lan

Both are warm, Blood-invigorating herbs used for menstrual disorders and postpartum Blood stasis. Ze Lan is milder in its Blood-moving action and also promotes urination and reduces swelling, making it better suited for mild Blood stasis with edema. Liu Ji Nu is more powerful at breaking up severe stasis and has the additional abilities to stop bleeding externally and resolve food stagnation, making it more versatile for trauma and multi-system presentations.

Wu Ling Zhi
Liu Ji Nu vs Wu Ling Zhi

Both enter the Blood level to dispel stasis and alleviate pain, and both are used for gynecological and trauma-related Blood stasis. Wu Ling Zhi (flying squirrel feces) is particularly strong at relieving pain from Blood stasis, especially chest and abdominal pain, and is classically paired with Pu Huang (Shi Xiao San). Liu Ji Nu has the unique advantage of stopping bleeding topically for wounds and treating food stagnation, and has a more aromatic quality that benefits the Spleen.

Common Substitutes & Adulterants

Related species and common adulterations to be aware of when sourcing Liu Ji Nu

The name "Liu Ji Nu" is used for several distinct plant species across different regions of China, making confusion a significant concern: 1. South Liu Ji Nu (南刘寄奴): Artemisia anomala S. Moore (Asteraceae). This is the species most consistent with classical descriptions and is used in Jiangsu, Zhejiang, Shanghai, Jiangxi, and Fujian. 2. North Liu Ji Nu (北刘寄奴): Siphonostegia chinensis Benth. (Scrophulariaceae/Orobanchaceae). This is the species recorded in the Chinese Pharmacopoeia (2020 edition). It is a completely different plant family, with cold nature rather than warm, and different therapeutic emphasis (clearing Heat and Dampness). Mainly produced in Hebei, Shandong, Henan, and northeast China. 3. Sichuan Liu Ji Nu: Artemisia lavandulifolia (narrow-leaved mugwort), also called Hong Chen Ai or Lu Hao. 4. Guangdong Liu Ji Nu: Artemisia lactiflora (white mugwort), also called Ya Jiao Ai. Practitioners should verify the botanical source when prescribing, as these species have substantially different properties and indications.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herb.

Toxicity Classification

Classical Chinese pharmacopoeia toxicity rating for Liu Ji Nu

Non-toxic

Liu Ji Nu is generally considered non-toxic at standard therapeutic doses. However, classical sources clearly warn that excessive internal use can cause diarrhea due to its strongly moving and descending nature. The Ben Cao Jing Shu states that because its nature is to "move swiftly through the Blood level, excessive use causes diarrhea." Pharmacological research notes some toxicity potential at high doses, including effects on smooth muscle. At standard decoction doses of 3 to 10g, the herb has a good safety profile with no serious adverse effects reported in clinical literature.

Contraindications

Situations where Liu Ji Nu should not be used or requires extra caution

Avoid

Pregnancy. Liu Ji Nu has strong Blood-moving and Blood-breaking properties that can stimulate uterine contractions and promote menstrual flow, posing a risk of miscarriage.

Caution

Qi and Blood deficiency without Blood stasis. The herb's nature is to strongly move and break Blood. In patients who are already deficient, it may further deplete Qi and Blood, worsening the underlying weakness.

Caution

Spleen deficiency with loose stools or diarrhea. Classical sources (Xin Xiu Ben Cao and Ben Cao Jing Shu) warn that excessive use causes diarrhea. Those already prone to loose stools should avoid it or use with great caution.

Caution

Heavy menstrual bleeding or active hemorrhage without Blood stasis. Although Liu Ji Nu can stop bleeding from traumatic wounds, its primary internal action is to break stasis and move Blood. Using it in active bleeding that is not caused by stasis could worsen the condition.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. Liu Ji Nu is classified among Blood-breaking and Blood-moving herbs. Its strong ability to invigorate Blood circulation, break stasis, and promote menstrual flow can stimulate uterine activity and potentially cause miscarriage. Classical and modern Chinese Materia Medica texts consistently list pregnancy as a contraindication (孕妇禁服/忌服). This herb should be strictly avoided throughout all stages of pregnancy.

Breastfeeding

No specific classical or modern data is available on the safety of Liu Ji Nu during breastfeeding. Given its strong Blood-moving properties and the general precautionary principle for nursing mothers, it should be used with caution and only under professional supervision if clinically necessary. It is prudent to avoid routine use while breastfeeding, as active compounds may transfer through breast milk and their effects on infants have not been studied.

Children

Liu Ji Nu has historical use in paediatric conditions. The Sheng Ji Zong Lu records a formula for persistent night crying in children combining Liu Ji Nu with Gan Cao and Di Long. Li Shizhen noted its use for childhood urinary bleeding (taken as fresh herb powder). For children, dosages should be reduced proportionally according to age and body weight, typically one-third to one-half of the adult dose. It should only be used under professional guidance and is not suitable for routine or long-term paediatric use due to its Blood-moving properties.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Liu Ji Nu

Anticoagulant and antiplatelet medications: Liu Ji Nu has demonstrated anti-platelet aggregation activity in pharmacological studies. Concurrent use with anticoagulants (such as warfarin or heparin) or antiplatelet drugs (such as aspirin or clopidogrel) may theoretically increase the risk of bleeding. Patients on such medications should inform their healthcare providers before using this herb. While direct clinical interaction studies specific to Artemisia anomala are lacking, the documented anti-platelet and Blood-moving pharmacology warrants caution.

Note: No other well-documented drug interactions specific to Liu Ji Nu have been reported in peer-reviewed literature. The herb contains coumarins, flavonoids, and volatile oils, which could in principle interact with drugs metabolized by cytochrome P450 enzymes, but this has not been specifically studied.

Dietary Advice

Foods and dietary considerations when taking Liu Ji Nu

While taking Liu Ji Nu, it is advisable to avoid excessive consumption of cold, raw foods that could impair Spleen function, as the herb itself can cause loose stools in susceptible individuals. Because Liu Ji Nu moves Blood vigorously, combining it with large amounts of alcohol may amplify its Blood-moving effects and should be done cautiously. No specific food incompatibilities are traditionally recorded.

Botanical Description

Physical characteristics and morphology of the Liu Ji Nu source plant

Liu Ji Nu (南刘寄奴) refers to the dried whole plant of Artemisia anomala S. Moore, a member of the Asteraceae (daisy) family. It is a perennial herb growing 80 to 150 cm tall with a distinctive aromatic scent. The stems are erect, often branching above the middle, with prominent longitudinal ridges and fine hairs on the upper portions where the flowering branches emerge.

The leaves are arranged alternately along the stem. The middle leaves are nearly leathery in texture, oblong or ovate-lance shaped, 7 to 11 cm long and 3 to 4 cm wide, with finely serrated margins and a covering of white hairs on the surface. The lower leaves wither and drop during flowering. The plant produces numerous small bell-shaped flower heads (capitula) that cluster densely into spike-like panicles. The involucral bracts are arranged in four rows and are pale yellow. The fruits (achenes) are small, oblong, and smooth. The plant grows in hillsides, roadsides, and forest edges across central and eastern China, preferring warm, humid environments.

Sourcing & Harvesting

Where Liu Ji Nu is sourced, when it's harvested or collected, and how to assess quality

Harvesting season

Late summer to early autumn (August to September), when the flowers are in bloom. The above-ground portion is cut, cleaned of impurities, and sun-dried.

Primary growing regions

South Liu Ji Nu (南刘寄奴, Artemisia anomala) is mainly produced in Jiangsu, Zhejiang, Jiangxi, Hunan, Hubei, and Sichuan provinces. It is most traditionally associated with the Jiangnan region (south of the Yangtze River), particularly Jiangsu and Zhejiang, where it has the longest history of use. The herb is also used in Shanghai, Fujian, and neighbouring areas. North Liu Ji Nu (北刘寄奴, Siphonostegia chinensis), a different species recorded in the Chinese Pharmacopoeia, is mainly produced in Hebei, Shandong, Henan, Jilin, and Heilongjiang provinces.

Quality indicators

Good quality South Liu Ji Nu (南刘寄奴) should have green leaves, yellow flower spikes, and a strong, distinctive aromatic fragrance. The stems should be intact, not overly woody, and the herb should feel light but not hollow. The whole plant should be free of excessive dirt, roots, or other impurities. Avoid material that has turned blackish (a sign of rain damage or improper drying) or that lacks fragrance. When rubbed between the fingers, the leaves should release a pleasant, slightly acrid aromatic scent.

Classical Texts

Key passages from the classical Chinese medical texts that describe Liu Ji Nu and its therapeutic uses

Xin Xiu Ben Cao (《新修本草》, Tang Dynasty)

Chinese: 主破血,下胀。

English: "It mainly breaks Blood [stasis] and reduces distension."

Kai Bao Ben Cao (《开宝本草》, Song Dynasty)

Chinese: 疗金疮,止血为要药;产后余疾,下血、止痛。

English: "It treats metal-inflicted wounds and is an essential medicine for stopping bleeding. For postpartum residual disorders, it moves Blood downward and stops pain."

Ri Hua Zi Ben Cao (《日华子本草》)

Chinese: 治心腹痛,下气水胀、血气,通妇人经脉症结,止霍乱水泻。

English: "It treats pain of the Heart and abdomen, descends Qi, relieves water distension and Blood-Qi [stagnation], opens women's channels and resolves masses, and stops cholera-like watery diarrhea."

Ben Cao Jing Shu (《本草经疏》)

Chinese: 刘寄奴草,其味苦,其气温...苦能降下,辛温通行,血得热则行,故能主破血下胀。然善走之性,又在血分,故多服则令人痢矣。昔人谓为金疮要药,又治产后余疾、下血止痛者,正以其行血迅速故也。

English: "Liu Ji Nu is bitter in flavour and warm in nature... Bitterness descends and moves downward; acrid warmth promotes free flow. Blood moves when it receives warmth, thus it can break Blood stasis and reduce distension. However, its nature is to move swiftly through the Blood level, so excessive use causes diarrhea. The ancients called it an essential wound medicine and used it for postpartum residual disorders, moving Blood downward and stopping pain, precisely because it circulates Blood so rapidly."

Historical Context

The history and evolution of Liu Ji Nu's use in Chinese medicine over the centuries

Liu Ji Nu holds the unique distinction of being the only Chinese medicinal herb named after an emperor. The name comes from Liu Yu (刘裕), whose childhood name was "Ji Nu" (寄奴), the founder of the Liu Song Dynasty (420 CE) during the Southern and Northern Dynasties period. According to the Song Shu (《宋书》) by Shen Yue and the Nan Shi (《南史》) by Li Yanshou, before Liu Yu became emperor he was hunting and shot a large serpent with an arrow. The next day, he followed the sound of a mortar and pestle into a grove and found several green-clad spirit boys grinding herbs to treat their injured serpent king. When they revealed the patient was wounded by "Liu Ji Nu," he announced himself and the boys fled, leaving behind the herb and its prepared paste. Liu Yu used this herb to heal battle wounds among his soldiers with remarkable success. Not knowing its proper name, the troops simply called it "Liu Ji Nu" after their commander.

The herb first appears in the pharmaceutical literature under this name in the Tang Dynasty's Xin Xiu Ben Cao (《新修本草》, 659 CE), which describes it as growing in Jiangnan with stems resembling mugwort. Subsequent texts including the Kai Bao Ben Cao, Ben Cao Tu Jing, and Ben Cao Gang Mu all expanded on its uses. Li Shizhen recorded the full legend in Ben Cao Gang Mu, Volume 15, citing Li Yanshou's Nan Shi. Over the centuries, its primary reputation was as a "golden wound essential medicine" (金疮要药) for traumatic injuries, while its Blood-moving and stasis-resolving functions were also applied to gynaecological conditions. In some regions, the South Liu Ji Nu variety also gained the folk name "Hua Shi Dan" (化食丹, "food-dissolving elixir") for its ability to relieve food stagnation.

Modern Research

2 published studies investigating the pharmacological effects or clinical outcomes of Liu Ji Nu

1

Comprehensive Review: Artemisia anomala S. Moore botany, traditional uses, phytochemistry, pharmacology and quality control (2023)

Liu J, Xiong P, Huang L, Zhang W, Song L, Hu H, Jia B, Liu X. Journal of Ethnopharmacology, 2023, 317, 116722.

This review compiled over 1300 years of traditional use and modern research on Artemisia anomala. It catalogued 125 isolated compounds including terpenoids, triterpenoids, flavonoids, phenylpropanoids, and volatile oils. The review confirmed significant anti-inflammatory, antibacterial, hepatoprotective, anti-platelet aggregation, and antioxidant activities, and noted the herb's wide modern clinical use for rheumatoid arthritis, dysmenorrhea, traumatic bleeding, hepatitis, and burns.

PubMed
2

In vitro study: Anti-inflammatory effects of Artemisia anomala ethanolic extract via NLRP3 inflammasome inhibition (2022)

Hong F, Zhao M, Xue LL, Ma X, Liu L, Cai XY, Zhang RJ, Li N, Wang L, Ni HF, Wu WS, Ye HY, Chen LJ. Journal of Ethnopharmacology, 2022, 295, 115377.

This preclinical study investigated the ethanolic extract of Artemisia anomala (EAA) in lipopolysaccharide-primed bone marrow-derived macrophages. EAA inhibited the activation of the NLRP3 inflammasome and reduced the release of the pro-inflammatory cytokine IL-1β, providing mechanistic evidence for the herb's traditional anti-inflammatory uses in conditions like enteritis, hepatitis, and rheumatism.

PubMed

Research on individual TCM herbs is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.