Xiong Gui Er Chen Tang

Chuanxiong and Angelica Two-Aged Decoction · 芎归二陈汤

A classical gynecological formula that combines phlegm-dissolving and dampness-drying herbs with blood-nourishing and Qi-moving herbs. It is designed for women whose menstrual irregularities or difficulty conceiving stem from phlegm and dampness blocking the reproductive system, often seen in those with a heavier body constitution.

Origin Wan Shi Nü Ke (万氏女科, Wan's Gynecology) by Wan Quan (万全, also known as Wan Mizhai 万密斋) — Míng dynasty, c. 1549–1575 CE
Composition 10 herbs
Dang Gui
King
Dang Gui
Chuan Xiong
King
Chuan Xiong
Ban Xia
Deputy
Ban Xia
Chen Pi
Deputy
Chen Pi
Xiang Fu
Assistant
Xiang Fu
Zhi Ke
Assistant
Zhi Ke
Fu Ling
Assistant
Fu Ling
Hua Shi
Assistant
Hua Shi
+2
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Xiong Gui Er Chen Tang is designed to correct these specific patterns.

Why Xiong Gui Er Chen Tang addresses this pattern

This is the primary pattern this formula was designed to treat. When the Spleen fails to properly transform and transport fluids, dampness accumulates and congeals into phlegm. In women, this phlegm-dampness can settle in the uterus and obstruct the Chong and Ren vessels (the extraordinary vessels governing menstruation and reproduction). The obstruction blocks the normal flow of Blood and Qi through the reproductive system, leading to delayed or scanty periods, or inability to conceive. The formula addresses this pattern on multiple fronts: Ban Xia and Chen Pi dry dampness and transform phlegm, Fu Ling and Hua Shi drain dampness downward, Xiang Fu and Zhi Ke move stagnant Qi, and Dang Gui with Chuan Xiong nourish and invigorate Blood to restore normal menstrual flow.

A practitioner would look for one or more of these signs

Late Menstruation

Periods arriving later than expected due to phlegm blocking the flow of Blood

Scanty Menstruation

Reduced menstrual flow, often pale in color

Infertility

Difficulty conceiving due to phlegm-dampness obstructing the uterus

Abdominal Distention

Bloating and fullness in the lower abdomen

Obesity

Tendency toward a heavier body constitution

Excessive Vaginal Discharge

Copious white or cloudy vaginal discharge

Nausea

Nausea or feeling of heaviness, especially after eating

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Xiong Gui Er Chen Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, conception requires free flow of Blood and Qi through the Chong and Ren vessels (the extraordinary meridians that govern the uterus and reproductive capacity). When the Spleen is weak and cannot properly transform fluids, dampness accumulates and gradually thickens into phlegm. This phlegm can settle in the uterus, creating a physical and functional blockage that prevents the uterus from receiving and nourishing a fertilized egg. This type of infertility is classically associated with women of heavier constitution who also show signs like fatigue, bloating, copious vaginal discharge, and late or scanty periods. The original text specifically states the formula treats women who are "obese with distension and fullness, phlegm-dampness obstruction, irregular menstruation, or inability to conceive."

Why Xiong Gui Er Chen Tang Helps

The formula simultaneously clears the obstruction and restores normal function. Ban Xia and Chen Pi dissolve the phlegm that is blocking the uterus, while Fu Ling and Hua Shi drain dampness downward to prevent re-accumulation. Xiang Fu and Zhi Ke restore smooth Qi flow through the lower abdomen. Crucially, Dang Gui and Chuan Xiong nourish and invigorate the Blood so that once the phlegm blockage clears, healthy Blood flow through the Chong and Ren vessels can resume, creating the conditions necessary for conception.

Also commonly used for

Late Menstruation

Due to phlegm-dampness obstructing the uterus, particularly in women with heavier body constitution

Scanty Menstruation

Reduced menstrual volume with pale color due to phlegm blocking Blood flow

Excessive Vaginal Discharge

Copious white vaginal discharge due to dampness in the lower body

Obesity

When accompanied by phlegm-dampness signs and menstrual irregularity

Polycystic Ovary Syndrome

When presenting with phlegm-dampness pattern features

What This Formula Does

Every TCM formula has a specific set of actions — here's what Xiong Gui Er Chen Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Xiong Gui Er Chen Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Xiong Gui Er Chen Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Xiong Gui Er Chen Tang works at the root level.

This formula addresses a pattern where two problems intertwine: Phlegm-Dampness accumulation and insufficient Blood movement in the uterus. In TCM, the Spleen is responsible for transforming and transporting fluids throughout the body. When the Spleen becomes weakened (from diet, overwork, or constitutional factors), it loses the ability to properly process fluids. These unprocessed fluids accumulate and thicken into what TCM calls "Phlegm" and "Dampness." Over time, this turbid material settles into the lower abdomen and blocks the Chong and Ren vessels, the two extraordinary channels most closely linked to menstruation and reproductive function.

When Phlegm-Dampness obstructs these channels, Blood cannot flow freely to the uterus at the appropriate time. This leads to delayed menstruation, scanty periods, or even amenorrhea. The person may also experience a sensation of heaviness in the body, chest fullness, nausea, vaginal discharge, and a greasy tongue coating. The pulse is typically slippery (indicating Phlegm) and possibly choppy or thin (indicating insufficient Blood flow).

The formula works by tackling both the root and the branch simultaneously. It dries the Dampness and dissolves the Phlegm that is blocking the channels, while also nourishing and gently moving the Blood so that menstrual flow can be restored. By strengthening the Spleen's fluid-processing capacity, it prevents new Phlegm from forming, addressing the underlying cause of the pattern.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly acrid and bitter with a sweet undertone — acrid to move Qi and Blood, bitter to dry Dampness, sweet to tonify the Spleen and harmonize.

Channels Entered

Ingredients

10 herbs

The herbs that make up Xiong Gui Er Chen Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Dang Gui

Dang Gui

Chinese Angelica root

Dosage 6 - 9g
Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen

Role in Xiong Gui Er Chen Tang

Nourishes and invigorates the Blood, regulates menstruation, and ensures that the phlegm-resolving strategy does not leave the Blood depleted. As a key gynecological herb, it addresses the underlying Blood deficiency that often accompanies phlegm-dampness in women with menstrual disorders.
Chuan Xiong

Chuan Xiong

Sichuan lovage rhizome

Dosage 3 - 6g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium

Role in Xiong Gui Er Chen Tang

Moves the Blood and promotes Qi circulation, working synergistically with Dang Gui to both nourish and activate Blood flow. Its ability to move Qi in the upper body and invigorate Blood throughout the channels helps break through stagnation caused by accumulated phlegm-dampness.
Deputies — Assists and enhances the King
Ban Xia

Ban Xia

Pinellia rhizome

Dosage 6 - 9g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs

Role in Xiong Gui Er Chen Tang

The primary phlegm-transforming herb in the formula. It dries dampness, expels phlegm, and directs rebellious Qi downward. It targets the root mechanism of phlegm production by restoring the Spleen and Stomach's ability to transform and transport fluids.
Chen Pi

Chen Pi

Tangerine peel

Dosage 6 - 9g
Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Spleen

Role in Xiong Gui Er Chen Tang

Regulates Qi and dries dampness, assisting Ban Xia in resolving phlegm. By promoting smooth Qi flow in the Spleen and Stomach, it helps prevent further phlegm accumulation and relieves chest and abdominal distension.
Assistants — Supports or moderates other herbs
Xiang Fu

Xiang Fu

Nutgrass Galingale Rhizome

Dosage 6 - 9g
Temperature Neutral
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Liver, Spleen, San Jiao (Triple Burner)

Role in Xiong Gui Er Chen Tang

A key Qi-regulating herb for gynecological conditions. It soothes the Liver, disperses stagnation, and regulates menstruation. Its addition strengthens the formula's ability to move Qi and disperse the stagnation that phlegm-dampness creates in the lower abdomen and uterus.
Zhi Ke

Zhi Ke

Bitter orange fruit

Dosage 6 - 9g
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn), Sour (酸 suān)
Organ Affinity Spleen, Stomach, Large Intestine, Lungs

Role in Xiong Gui Er Chen Tang

Moves Qi and reduces distension, reinforcing the Qi-regulating action of Xiang Fu and Chen Pi. It helps open the Qi dynamic in the Middle Burner, further alleviating the bloating and fullness characteristic of phlegm-dampness obstruction.
Fu Ling

Fu Ling

Poria

Dosage 6 - 9g
Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys

Role in Xiong Gui Er Chen Tang

Strengthens the Spleen and leaches out dampness through the urinary pathway. By addressing the root cause of phlegm (Spleen weakness leading to fluid accumulation), it prevents the regeneration of pathological dampness.
Hua Shi

Hua Shi

Talc

Dosage 6 - 9g
Temperature Cold
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Stomach, Urinary Bladder

Role in Xiong Gui Er Chen Tang

Clears heat and promotes urination, providing a downward drainage route for dampness. It strengthens the formula's ability to resolve dampness and phlegm, particularly useful when dampness generates mild heat.
Envoys — Directs the formula to its target
Gan Cao

Gan Cao

Licorice root

Dosage 3 - 6g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Xiong Gui Er Chen Tang

Tonifies the Spleen and harmonizes all the other herbs in the formula. It moderates the drying nature of Ban Xia and Chen Pi, ensuring the formula does not overly deplete fluids while still resolving dampness.
Sheng Jiang

Sheng Jiang

Fresh ginger rhizome

Dosage 3 - 6g
Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Spleen, Stomach

Role in Xiong Gui Er Chen Tang

Warms the Stomach, assists Ban Xia in transforming phlegm, and reduces Ban Xia's potential toxicity. It also harmonizes the Stomach to control nausea and promotes the smooth flow of Qi.

Why This Combination Works

How the herbs in Xiong Gui Er Chen Tang complement each other

Overall strategy

This formula addresses the intertwined problems of phlegm-dampness accumulation and Blood deficiency with stagnation in the uterus. The prescription logic combines the classic phlegm-resolving Er Chen Tang base with Blood-nourishing and Qi-moving herbs, tackling both the turbid excess blocking the reproductive system and the underlying insufficiency of Blood that drives menstrual irregularity and infertility.

King herbs

Dang Gui and Chuan Xiong serve as the King herbs, giving the formula its distinctive gynecological focus. Dang Gui nourishes and moves Blood, while Chuan Xiong invigorates Blood circulation and promotes Qi movement. Together they ensure that while phlegm is being resolved, the Blood is simultaneously replenished and kept flowing freely through the Chong and Ren vessels that govern menstruation and fertility.

Deputy herbs

Ban Xia and Chen Pi form the core of the Er Chen Tang structure. Ban Xia is the primary phlegm-transforming agent, drying dampness and directing turbidity downward. Chen Pi regulates Qi and assists in drying dampness, ensuring that the Middle Burner's transport function is restored so phlegm ceases to be produced.

Assistant herbs

Xiang Fu and Zhi Ke are reinforcing assistants that strengthen the Qi-moving dimension of the formula, particularly important for dispersing stagnation in the Liver channel and lower abdomen. Xiang Fu is especially valued in gynecology for its ability to regulate menstruation through Qi movement. Fu Ling is a reinforcing assistant that strengthens the Spleen and drains dampness downward via urination, addressing the root cause of phlegm production. Hua Shi serves as a reinforcing assistant that provides an additional route for draining dampness and mild heat through the urinary pathway.

Envoy herbs

Gan Cao harmonizes the formula and tonifies the Spleen, moderating the drying herbs so they do not injure fluids. Sheng Jiang warms the Stomach, assists Ban Xia in phlegm transformation, and reduces Ban Xia's harshness.

Notable synergies

Dang Gui paired with Chuan Xiong (the classic "Xiong Gui" combination from Si Wu Tang) creates a powerful Blood-nourishing and Blood-moving pair that neither herb achieves alone. Ban Xia paired with Chen Pi provides mutual reinforcement in drying dampness and transforming phlegm. Xiang Fu paired with Chuan Xiong moves both Qi and Blood simultaneously, helping to break through the combined phlegm and stagnation in the uterus.

How to Prepare

Traditional preparation instructions for Xiong Gui Er Chen Tang

Combine all herbs and soak in approximately 600 mL of water for 30 minutes. Add 7 slices of fresh ginger (Sheng Jiang). Bring to a boil, then simmer on low heat for 25–30 minutes until the liquid reduces to approximately 250–300 mL. Strain and divide into two portions. Take warm, one portion in the morning and one in the evening, ideally between meals.

Common Modifications

How practitioners adapt Xiong Gui Er Chen Tang for specific situations

Added
Bai Zhu

9g, strengthens the Spleen and dries dampness

Dang Shen

9g, tonifies Spleen Qi to address underlying deficiency

When the Spleen is severely weakened, simply resolving phlegm is insufficient. Adding Bai Zhu and Dang Shen directly tonifies the Spleen so it can resume its fluid-transforming function and prevent phlegm from re-forming.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Xiong Gui Er Chen Tang should not be used or requires extra caution

Caution

Yin deficiency with Heat signs (dry mouth, night sweats, red tongue with scanty coating). The drying and warming nature of this formula can further damage Yin fluids.

Avoid

Heavy menstrual bleeding or active uterine hemorrhage. Dang Gui and Chuan Xiong invigorate Blood movement and may worsen bleeding.

Avoid

Pregnancy. Chuan Xiong and Ban Xia are traditionally cautioned or contraindicated in pregnancy due to their Blood-moving and downward-directing properties.

Caution

Dry, non-productive cough without signs of Dampness. This formula is designed for Phlegm-Dampness patterns and is inappropriate when there is no Dampness present.

Caution

Blood deficiency without concurrent Phlegm-Dampness. If Blood deficiency is the sole issue, a purely Blood-tonifying formula is more appropriate.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. Chuan Xiong (Ligusticum) is a Blood-invigorating herb with known downward-directing action that can stimulate uterine contractions. Ban Xia (Pinellia) is traditionally listed among herbs prohibited during pregnancy (妊娠禁忌) due to its potential to disturb fetal stability. Dang Gui (Angelica sinensis) also promotes Blood circulation and may increase the risk of uterine bleeding. The combination of these three herbs makes this formula unsuitable for pregnant women.

Breastfeeding

Use with caution during breastfeeding. Ban Xia (Pinellia) has mild toxicity in its unprocessed form, though the formula uses the processed (Fa Ban Xia) variety, which is considered safer. Components may pass into breast milk in small quantities. Chuan Xiong's Blood-invigorating properties are unlikely to pose significant risk to a nursing infant at standard doses. There is no strong classical prohibition against use during breastfeeding, but consultation with a qualified practitioner is recommended, particularly in the early postpartum period when the mother's constitution may be depleted.

Children

This formula is designed for gynecological conditions in adult women, particularly menstrual irregularity due to Phlegm-Dampness. It is not typically indicated for pediatric use. If a modified version were considered for an adolescent girl experiencing late onset of menarche with clear Phlegm-Dampness signs, dosages would need to be reduced to approximately 50-70% of the adult dose depending on age and body weight, and treatment should be supervised by an experienced practitioner. Ban Xia requires careful dosing in younger patients due to its mild inherent toxicity.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Xiong Gui Er Chen Tang

Anticoagulant and antiplatelet medications (warfarin, heparin, aspirin, clopidogrel): Both Dang Gui (Dong Quai) and Chuan Xiong (Ligusticum) have documented Blood-invigorating properties. Dang Gui contains coumarin derivatives and has been specifically identified in pharmacological literature as having potential to increase warfarin's anticoagulant effect and raise bleeding risk. Concurrent use with anticoagulants or antiplatelet drugs should be avoided or closely monitored with INR testing.

Gan Cao (Licorice root) interactions: Gan Cao contains glycyrrhizin, which can cause potassium depletion and sodium retention. It may interact with antihypertensive medications (reducing their effectiveness), diuretics (worsening potassium loss), corticosteroids (potentiating side effects), and cardiac glycosides such as digoxin (hypokalemia increasing digoxin toxicity).

Hypoglycemic medications: Dang Gui may have mild blood glucose-lowering effects. Patients on insulin or oral hypoglycemic agents should monitor blood sugar levels if taking this formula concurrently.

Usage Guidance

Practical advice for getting the most out of Xiong Gui Er Chen Tang

Best time to take

30 minutes after meals, twice daily (morning and evening). Traditionally taken as a warm decoction.

Typical duration

Typically prescribed for 2-4 weeks, adjusted based on menstrual cycle response. Often taken for 1-3 menstrual cycles with reassessment by the practitioner.

Dietary advice

Avoid cold, raw, and greasy foods while taking this formula, as these contribute to Dampness and Phlegm production, directly counteracting the formula's therapeutic purpose. Dairy products, excessive sweets, deep-fried foods, and heavy starchy dishes should be minimized. Favor warm, lightly cooked meals with mild aromatic spices (such as fresh ginger or dried tangerine peel in cooking) that support the Spleen's digestive function. Avoid alcohol, which generates Dampness and Heat. Light, easily digestible grains such as rice congee, millet, and barley are supportive. Small amounts of cooked leafy greens and warming soups are beneficial.

Xiong Gui Er Chen Tang originates from Wan Shi Nü Ke (万氏女科, Wan's Gynecology) by Wan Quan (万全, also known as Wan Mizhai 万密斋) Míng dynasty, c. 1549–1575 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Xiong Gui Er Chen Tang and its clinical use

Wan Quan (万全), Wan Shi Fu Ren Ke (《万氏妇人科》), on the pathology of late menstruation due to Phlegm-Dampness:

Wan Quan taught that in women whose menstruation arrives late, one must consider whether Phlegm-Dampness is obstructing the flow of Blood. When the Spleen fails to transform and transport fluids properly, Dampness collects and congeals into Phlegm. This Phlegm then blocks the Chong and Ren vessels, preventing Blood from descending at the proper time. The treatment principle is to dry Dampness, transform Phlegm, and simultaneously nourish and move the Blood so that menstruation can resume its normal cycle.

On the relationship between Phlegm and Blood in gynecology:

Wan Quan's approach reflects the classical teaching that "treating Phlegm must address the Spleen, and treating menstruation must address the Blood" (治痰须理脾,调经须理血). His innovation was combining these two strategies in a single formula, recognizing that Phlegm and Blood stasis frequently coexist in gynecological conditions.

Historical Context

How Xiong Gui Er Chen Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Xiong Gui Er Chen Tang originates from the Wan Shi Fu Ren Ke (《万氏妇人科》, "Wan's Gynecology"), written by the Ming Dynasty physician Wan Quan (万全, courtesy name Mizhai 密斋, c. 1499–1582). Wan Quan came from a distinguished three-generation medical lineage based in Luotian, Hubei province. While his family was originally famous for pediatrics ("the Wan family pediatrics"), Wan Quan himself expanded into gynecology and became equally accomplished in that field. He was later honored with the title "Medical Sage" (医圣) by the Kangxi Emperor during the early Qing Dynasty.

The formula represents a clever modification of Er Chen Tang (二陈汤, "Two Aged Decoction"), one of the most foundational Phlegm-resolving formulas in all of Chinese medicine. Er Chen Tang was first recorded in the Song Dynasty text Tai Ping Hui Min He Ji Ju Fang (《太平惠民和剂局方》) and became the base formula for dozens of later variations. Wan Quan's insight was to add Dang Gui and Chuan Xiong, the two key Blood-nourishing and Blood-moving herbs from Si Wu Tang (四物汤, "Four Substances Decoction"), to the Phlegm-resolving base. This created a formula uniquely suited for gynecological conditions where Phlegm-Dampness and Blood deficiency or stasis overlap, a pattern combination that earlier gynecologists had recognized but lacked a dedicated formula to address.

Wan Quan's broader gynecological philosophy emphasized that menstrual regulation should focus on "regulating Qi and tonifying the Heart and Spleen" (调经专以理气补心脾为主). His approach to late menstruation from Phlegm-Dampness reflects the influence of Zhu Danxi's teachings on Phlegm as a central pathological product, combined with the Blood-focused tradition of gynecological medicine.