Er Qing Gao

Two Greens Paste · 二青膏

An external paste used to clear Heat-toxins and reduce hot, painful swelling in conditions like boils, carbuncles, abscesses, and inflamed skin lesions. It is applied topically to the affected area, not taken internally. The formula combines cooling, detoxifying herbs with ingredients that draw out pus and promote tissue healing.

Origin Wài Kē Zhèng Zōng (外科正宗, Orthodox Manual of External Medicine) by Chén Shígōng (陈实功) — Míng dynasty, 1617 CE
Composition 11 herbs
Qing Dai
King
Qing Dai
Fu Rong Ye
King
Fu Rong Ye
Mang Xiao
Deputy
Mang Xiao
Shi Gao
Deputy
Shi Gao
Da Huang
Assistant
Da Huang
Huang Qi
Assistant
Huang Qi
Tian Hua Fen
Assistant
Tian Hua Fen
Chi Xiao Dou
Assistant
Chi Xiao Dou
+3
more
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Er Qing Gao is designed to correct these specific patterns.

Why Er Qing Gao addresses this pattern

When Toxic-Heat accumulates in the skin and flesh, it causes local redness, swelling, heat, and pain, potentially progressing to suppuration (pus formation). The toxins congest the local area, blocking the flow of Qi and Blood and causing tissue damage. Er Qing Gao directly addresses this by applying powerful cooling, detoxifying agents (Qing Dai, Fu Rong Ye, Da Huang, Huang Bai) to the site. Mang Xiao softens and disperses the hard, hot mass. Tian Hua Fen and Bai Zhi draw out the pus, allowing the accumulated toxin to drain. Once the Heat is cleared and the toxin resolved, Bai Ji and Long Gu promote tissue healing and wound closure.

A practitioner would look for one or more of these signs

Boils

Hot, red, painful skin nodules with possible pus

Carbuncles

Large, deep-seated infected swellings

Acute Breast Abscesses

Localized collection of pus with surrounding inflammation

Skin Dryness

Local redness and heat at the lesion

Swelling

Hard or soft swelling that is hot and tender to touch

Localized Pain

Throbbing or burning pain at the affected site

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Er Qing Gao when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Toxic-Heat

TCM Interpretation

In TCM, boils (furuncles) are understood as the result of Toxic-Heat lodging in the skin and flesh. This may arise from external exposure to pathogenic Heat or Dampness, or from internal Heat (often linked to dietary excess of rich, greasy, or spicy foods) that pushes outward to the skin surface. The local accumulation of Heat-toxin obstructs Qi and Blood flow, causing the tissue to swell, redden, and become painful. As the Heat 'cooks' the flesh, pus forms. The condition reflects a struggle between the body's upright Qi and the pathogenic toxin.

Why Er Qing Gao Helps

Er Qing Gao is applied directly to the boil, delivering its cooling, detoxifying ingredients right where they are needed. Qing Dai and Fu Rong Ye, the two King herbs, powerfully clear the Heat-toxin at the site, reducing redness and pain. Mang Xiao softens and disperses the hard swelling. If pus has begun to form, Bai Zhi and Tian Hua Fen help draw it to the surface for discharge. Once the acute inflammation resolves, Bai Ji and Long Gu promote healing and closure of the lesion. The external application avoids systemic side effects while concentrating the therapeutic action at the affected site.

Also commonly used for

Carbuncles

Large infected swellings in the skin and subcutaneous tissue

Mastitis

Inflammatory breast tissue with Heat-toxin accumulation

Cellulitis

Spreading skin and soft tissue inflammation

Trauma

Soft tissue injuries with local swelling and bruising

Sprains

Joint sprains with hot, painful swelling

Insect Bites

Inflamed or infected insect bites

What This Formula Does

Every TCM formula has a specific set of actions — here's what Er Qing Gao does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Er Qing Gao is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Er Qing Gao performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Er Qing Gao works at the root level.

Er Qing Gao addresses conditions where Toxic-Heat (热毒) has accumulated in the local flesh and channels, causing tissue inflammation and swelling. In TCM theory, when external pathogenic factors or internal Heat toxins gather in a particular area, they obstruct the flow of Qi and Blood through the local channels. This obstruction generates further Heat and stagnation, creating a vicious cycle: the blocked Qi and Blood stagnate, producing swelling and pain, while the concentrated Heat transforms into toxin that corrupts the flesh, potentially forming pus.

Clinically, this mechanism manifests as red, hot, swollen, and painful lesions such as boils (疖), carbuncles (痈), abscesses, acute breast inflammation (乳痈), and traumatic swelling with local Heat signs. The skin over the affected area is typically taut, warm or hot to the touch, and tender. There may also be general signs of Heat such as fever and a rapid pulse. The tongue may be red with a yellow coating. As an external plaster, Er Qing Gao works directly at the site of pathology, delivering its cold, Heat-clearing, and toxin-resolving properties through the skin to the underlying affected tissues, thereby interrupting the cycle of Heat accumulation and Qi-Blood stagnation.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Cold

Taste Profile

Predominantly bitter and salty, with cooling therapeutic action — bitter to drain Fire and dry Dampness, salty to soften hardness and disperse swelling.

Target Organs

Ingredients

11 herbs

The herbs that make up Er Qing Gao, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Kings — Main ingredient driving the formula
Qing Dai

Qing Dai

Indigo Naturalis

Dosage 6 - 9g
Temperature Cold
Taste Salty (咸 xián)
Organ Affinity Liver, Lungs

Role in Er Qing Gao

The primary Heat-clearing and toxin-resolving herb. Qing Dai (Natural Indigo) is bitter and cold, powerfully clears Fire-toxins from the Blood and skin, reduces swelling, and relieves pain. Its deep cooling nature directly targets the core pathomechanism of Toxic-Heat accumulation.
Fu Rong Ye

Fu Rong Ye

Cotton Rose Hibiscus Leaf

Dosage 9 - 15g
Temperature Cool
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Liver
Preparation Fresh leaves may be pounded directly; dried leaves are ground to powder

Role in Er Qing Gao

The second principal herb, Fu Rong Ye (Hibiscus mutabilis Leaf) clears Heat, resolves toxins, expels pus, and reduces swelling. It is a classical external-use herb for sores and abscesses, working in tandem with Qing Dai to form the formula's core detoxifying action. The name 'Er Qing' (Double Blue/Dark) refers to these two dark-colored King herbs.
Deputies — Assists and enhances the King
Mang Xiao

Mang Xiao

Mirabilite

Dosage 6 - 9g
Temperature Cold
Taste Bitter (苦 kǔ), Salty (咸 xián)
Organ Affinity Stomach, Large Intestine

Role in Er Qing Gao

Mang Xiao (Mirabilite/Sodium Sulfate) is salty and cold. Applied externally, it softens hardness, disperses swelling and nodules, and clears Heat. It strengthens the Kings' ability to reduce hot, hard, swollen lesions.
Shi Gao

Shi Gao

Gypsum

Dosage 9 - 15g
Temperature Cold
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Lungs, Stomach
Preparation Used in calcined form (Duan Shi Gao, 煅石膏)

Role in Er Qing Gao

Calcined Gypsum (Duan Shi Gao) is used externally to clear Heat, absorb moisture, and promote tissue healing. It supports the formula's cooling strategy and helps generate new tissue at the lesion site.
Assistants — Supports or moderates other herbs
Da Huang

Da Huang

Rhubarb root and rhizome

Dosage 6 - 9g
Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Spleen, Stomach, Large Intestine, Liver, Pericardium

Role in Er Qing Gao

Da Huang (Rhubarb) used externally clears Heat-toxins, invigorates Blood, and disperses stasis. It helps break down accumulated Heat and stagnant Blood in the affected tissue, reducing redness and swelling.
Huang Qi

Huang Qi

Astragalus root

Dosage 6 - 9g
Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs

Role in Er Qing Gao

Huang Bai (Phellodendron Bark) clears Heat, dries Dampness, and resolves toxins. It reinforces the formula's ability to address Damp-Heat and toxins in the skin, particularly useful when sores weep or ooze fluid.
Tian Hua Fen

Tian Hua Fen

Trichosanthes root

Dosage 6 - 9g
Temperature Cool
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Stomach

Role in Er Qing Gao

Tian Hua Fen (Trichosanthes Root) clears Heat, generates fluids, reduces swelling, and expels pus. In external application, it is classically used to disperse clumps and help draw out pus from abscesses.
Chi Xiao Dou

Chi Xiao Dou

Adzuki bean

Dosage 9 - 15g
Temperature Neutral
Taste Sweet (甘 gān), Sour (酸 suān)
Organ Affinity Heart, Small Intestine

Role in Er Qing Gao

Chi Xiao Dou (Aduki Bean) clears Heat, resolves Dampness, and disperses swelling. Used externally, it helps reduce puffiness and fluid accumulation in inflamed tissues.
Bai Zhi

Bai Zhi

Dahurian angelica root

Dosage 6 - 9g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Stomach, Large Intestine

Role in Er Qing Gao

Bai Zhi (Angelica Dahurica Root) reduces swelling, expels pus, and alleviates pain. It is a key external medicine herb that promotes the discharge of pus from mature abscesses and helps relieve the pain of inflamed sores.
Bai Ji

Bai Ji

Common Bletilla Tuber

Dosage 6 - 9g
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sweet (甘 gān), Astringent (涩 sè)
Organ Affinity Lungs, Liver, Stomach

Role in Er Qing Gao

Bai Ji (Bletilla Rhizome) astringes and stops bleeding, reduces swelling, and promotes tissue regeneration. It helps close wounds and supports healing once the Heat-toxin has been cleared.
Long Gu

Long Gu

Dragon Bone (fossilised mammal bone)

Dosage 9 - 15g
Temperature Neutral
Taste Sweet (甘 gān), Astringent (涩 sè)
Organ Affinity Heart, Liver, Kidneys
Preparation Used in calcined form (Duan Long Gu, 煅龙骨)

Role in Er Qing Gao

Long Gu (Dragon Bone/Fossilized Bone) used externally absorbs moisture, astringes sores, and promotes tissue healing. It helps dry weeping lesions and supports the generation of new skin tissue.

Why This Combination Works

How the herbs in Er Qing Gao complement each other

Overall strategy

Er Qing Gao addresses acute Toxic-Heat accumulating in the flesh and skin, presenting as hot, red, painful swelling such as boils, carbuncles, and abscesses. The formula combines powerful Heat-clearing and toxin-resolving herbs with ingredients that soften hardness, draw out pus, and promote tissue repair, all delivered directly to the lesion as an external paste.

King herbs

Qing Dai and Fu Rong Ye together form the core of the formula and give it its name ('Er Qing' meaning 'Double Blue/Dark'). Both are bitter and cold, excelling at clearing Fire-toxins and dispersing swelling from the skin and flesh. Qing Dai powerfully cools the Blood and resolves toxins, while Fu Rong Ye is a classical topical herb for sores, specifically indicated for expelling pus and reducing swollen masses. Together they mount a strong assault on the Heat-toxin at the core of the lesion.

Deputy herbs

Mang Xiao, salty and cold, softens hardness and disperses bound swellings, complementing the Kings by breaking down the hard, nodular quality of the lesion. Calcined Shi Gao clears residual Heat, absorbs excess moisture, and promotes tissue regeneration at the wound surface.

Assistant herbs

Da Huang clears Heat and invigorates Blood stasis in the affected tissue (reinforcing). Huang Bai dries Dampness and resolves toxins, particularly useful when lesions weep fluid (reinforcing). Tian Hua Fen and Bai Zhi both disperse clumping and thrust out pus, facilitating the discharge of suppurated material (reinforcing). Chi Xiao Dou clears Damp-Heat and reduces puffy swelling (reinforcing). Bai Ji astringes the sore and promotes new tissue growth once the toxin is cleared (restraining, in the sense that it begins the healing phase). Long Gu absorbs moisture and astringes weeping lesions, supporting wound closure (restraining).

Notable synergies

Qing Dai and Fu Rong Ye together provide a synergistic cooling and detoxifying action far stronger than either alone, making this pair the formula's signature. Bai Zhi and Tian Hua Fen together promote the expulsion of pus while reducing pain. Bai Ji and Long Gu work as a pair to astringe, dry, and promote healing once the acute toxin has been resolved.

How to Prepare

Traditional preparation instructions for Er Qing Gao

Grind all dry ingredients into a very fine powder and mix thoroughly. Combine the powder with an appropriate amount of sesame oil (Ma You, 麻油) or honey (Feng Mi, 蜂蜜), or mix with fresh egg white (Ji Zi Qing, 鸡子清) or vinegar (Cu, 醋) to form a smooth, spreadable paste. Apply the paste directly to the affected area, covering with clean cloth or gauze. Change the dressing once or twice daily, cleaning the area before each new application. If fresh Fu Rong Ye (Hibiscus Leaves) are available, they may be pounded fresh and incorporated into the paste for stronger effect.

Common Modifications

How practitioners adapt Er Qing Gao for specific situations

Added
Pu Gong Ying

15 - 30g, strengthens Heat-clearing and toxin-resolving action

Jin Yin Hua

9 - 15g, powdered and added to the paste for enhanced detoxification

When the Heat-toxin is particularly severe with intense redness and burning, adding strong Heat-clearing and detoxifying herbs like Pu Gong Ying and Jin Yin Hua powder intensifies the formula's core cooling action.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Er Qing Gao should not be used or requires extra caution

Avoid

Do not apply to open wounds, ulcerated or broken skin, as the formula may cause further irritation, delay healing, or promote infection.

Avoid

Not suitable for Yin-type sores (those that are pale, flat, non-inflamed, cold to the touch, with thin watery discharge) as these indicate cold/deficiency rather than Toxic-Heat. Using a cold, Heat-clearing formula on a Yin-type sore may worsen the condition.

Avoid

Individuals with known allergy or sensitivity to indigo (Qing Dai) or any other ingredient should avoid use. A small patch test on intact skin is advisable before broader application.

Caution

Use with caution in individuals with generally cold constitutions or Spleen-Stomach deficiency cold, as the formula is predominantly cold in nature and may impair local circulation if used excessively.

Caution

Avoid application near mucous membranes (eyes, mouth, nasal passages, genitalia), as Mang Xiao and other ingredients can cause chemical irritation to sensitive tissues.

Caution

Use with caution when sores have already ruptured and begun draining pus. The formula is primarily designed for the early and middle stages of swelling before ulceration.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Although Er Qing Gao is an external topical formula (not taken internally), it contains Mang Xiao (芒硝, Mirabilite), which is classically contraindicated in pregnancy. Mang Xiao can be absorbed through the skin in small amounts, and its traditional classification as a substance that may stimulate uterine activity warrants caution. Pregnant women should consult a qualified practitioner before using this formula, and it should not be applied over large areas of skin or for prolonged periods during pregnancy.

Breastfeeding

Use with caution during breastfeeding. As an external topical formula, systemic absorption is limited, but Mang Xiao (芒硝) can be absorbed through the skin in small amounts and may theoretically pass into breast milk. When used on the breast itself (as for mastitis), the residue must be thoroughly cleaned before nursing to prevent the infant from ingesting any of the formula's ingredients. Consult a qualified practitioner before use during breastfeeding.

Children

Er Qing Gao is an external topical formula and may be used on children with appropriate caution. Apply a thinner layer than for adults, and reduce the area and duration of application. Children's skin is more permeable and sensitive than adult skin, so close monitoring for any local irritation (redness, rash, itching) is important. Discontinue immediately if adverse skin reactions occur. Not recommended for infants under 1 year of age without direct supervision from a qualified practitioner. Ensure the child cannot touch or ingest the plaster.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Er Qing Gao

As an external topical formula, Er Qing Gao has a lower risk of systemic drug interactions compared to internal formulas. However, the following precautions apply:

  • Topical medications: Do not apply Er Qing Gao simultaneously with other topical preparations (antibiotics, corticosteroid creams, antifungals) on the same area, as unpredictable chemical interactions or altered absorption may occur.
  • Mang Xiao (芒硝, sodium sulfate): Although applied externally, if used over large body surface areas, percutaneous absorption of sodium sulfate could theoretically affect electrolyte balance in individuals taking diuretics or medications sensitive to sodium levels.
  • Anticoagulant or antiplatelet therapy: Some ingredients in the formula may have mild Blood-moving properties when absorbed; patients on warfarin or similar agents should use with caution and inform their prescriber.

Usage Guidance

Practical advice for getting the most out of Er Qing Gao

Best time to take

Apply to the affected area once or twice daily (morning and evening), on clean, dry, intact skin. Replace the plaster when it dries out.

Typical duration

Applied externally once or twice daily for 3–10 days depending on symptom severity; reassess if no improvement within 5 days.

Dietary advice

While using this external formula for active Hot-type sores or abscesses, avoid foods that may aggravate Heat and toxin accumulation: spicy and pungent foods (chili, garlic, raw onion, ginger), deep-fried and greasy foods, alcohol, shellfish and other "hair-trigger" foods (发物 fa wu) such as shrimp, crab, lamb, and rooster. Favor cooling, bland foods such as mung bean soup, winter melon, cucumber, pear, and leafy greens to support the body's Heat-clearing process from within.

Er Qing Gao originates from Wài Kē Zhèng Zōng (外科正宗, Orthodox Manual of External Medicine) by Chén Shígōng (陈实功) Míng dynasty, 1617 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Er Qing Gao and its clinical use

Er Qing Gao originates from the Wai Ke Zheng Zong (外科正宗, Orthodox Manual of External Medicine) by Chen Shigong (陈实功), published in 1617 during the Ming Dynasty. As a specialized external plaster in the tradition of TCM surgery (Wai Ke), detailed classical quotes about this specific formula are embedded within the broader clinical discussions of sore and abscess management in the source text rather than appearing as standalone aphorisms. The formula name "Er Qing" (二青, "Double Dark/Blue-Green") refers to its two principal herbs, Qing Dai (青黛, Natural Indigo) and Fu Rong Ye (芙蓉叶, Hibiscus mutabilis leaf), both of which share a deep blue-green hue and cold, bitter nature suited to clearing Heat toxins from the flesh.

Historical Context

How Er Qing Gao evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Er Qing Gao comes from the Wai Ke Zheng Zong (外科正宗, Orthodox Manual of External Medicine), written by the renowned Ming Dynasty surgeon Chen Shigong (陈实功) and published in 1617. Chen Shigong was one of the most influential figures in the history of Chinese external medicine (Wai Ke), and his text remains a foundational reference for the surgical branch of TCM. The Wai Ke Zheng Zong systematized the diagnosis and treatment of sores, carbuncles, and other external conditions, and contained numerous formulas for plasters, washes, and powders designed for topical application.

The formula name "Er Qing Gao" literally means "Double Blue-Green Plaster," referring to its two chief herbs that share both the character "qing" (青, blue-green/dark) in their names and a cold, bitter, Heat-clearing nature: Qing Dai (青黛, Natural Indigo) and Fu Rong Ye (芙蓉叶, the leaf of Hibiscus mutabilis, sometimes called the "frost-defying flower"). This naming convention reflects the classical practice of titling formulas after their principal ingredients or their defining characteristics.