Ding Xiang Shi Di Tang

Clove and Persimmon Calyx Decoction · 丁香柿蒂汤

A classical formula used to warm the Stomach, strengthen digestion, and stop persistent hiccups (hiccough), belching, or nausea caused by Cold and weakness in the digestive system. It is especially suited for people whose hiccups worsen with cold food or weather and improve with warmth.

Origin Zhèng Yīn Mài Zhì (症因脈治) by Qín Jǐngmíng (秦景明) — Míng dynasty (written ~1641 CE), published Qīng dynasty, 1706 CE
Composition 4 herbs
Ding Xiang
King
Ding Xiang
Shi Di
King
Shi Di
Ren Shen
Deputy
Ren Shen
Sheng Jiang
Assistant
Sheng Jiang
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Ding Xiang Shi Di Tang is designed to correct these specific patterns.

Why Ding Xiang Shi Di Tang addresses this pattern

This is the primary pattern treated by Ding Xiang Shi Di Tang. When the Stomach is both deficient in Qi and invaded by Cold, it loses its essential ability to move Qi downward. Instead, Qi rebels upward, producing persistent hiccups, belching, or vomiting. The formula directly addresses this by warming the Stomach with Ding Xiang and Sheng Jiang, restoring the descending function with Shi Di, and replenishing the depleted Qi with Ren Shen. The combination of warming, descending, and tonifying actions matches the compound nature of this pattern perfectly.

A practitioner would look for one or more of these signs

Hiccups

Persistent, continuous hiccups that worsen with cold and improve with warmth

Nausea

Nausea or vomiting, especially after cold food or drink

Epigastric Coldness

Stifling sensation or fullness in the upper abdomen and chest

Poor Appetite

Reduced appetite due to Stomach weakness

Cold Limbs

Cold hands and feet in severe cases

Pale Tongue

Pale tongue with a white coating

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Ding Xiang Shi Di Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, hiccups (known as 呃逆, è nì) are understood as Stomach Qi rebelling upward instead of descending as it normally should. The Stomach is meant to send food and Qi downward, and when this function is impaired, Qi surges up through the diaphragm, producing the characteristic involuntary sound. There are both Hot and Cold types of hiccups. In the Cold-deficiency type that Ding Xiang Shi Di Tang addresses, the Stomach has become weakened (Qi deficiency) and Cold has settled in the middle burner. The Cold constricts and disrupts the Stomach's descending mechanism, causing Qi to repeatedly rebel upward. Key signs pointing to this Cold pattern include: hiccups that worsen after consuming cold foods or drinks, improve with warmth, a pale tongue with white coating, and a deep, slow pulse.

Why Ding Xiang Shi Di Tang Helps

Ding Xiang Shi Di Tang is considered the primary formula for Cold-type persistent hiccups. The two King herbs, Ding Xiang (Clove) and Shi Di (Persimmon Calyx), form one of the most recognized herb pairs in the entire TCM pharmacopoeia for stopping hiccups. Ding Xiang warms the Stomach and propels Qi downward, while Shi Di is the single most specific anti-hiccup herb in the materia medica, with a strong astringent, descending action on Stomach Qi. Ren Shen addresses the underlying Qi deficiency that allows Cold to take hold, and Sheng Jiang reinforces the warming and anti-nausea effects. Clinical studies have reported this formula effective for intractable hiccups, with one study showing resolution of hiccups in 31 out of 34 patients over a 5-day course.

Also commonly used for

Nausea

Nausea with a cold-deficiency pattern

Epigastric Fullness And Pain Relieved By Vomiting

Vomiting of clear fluid due to Stomach Cold

Chronic Gastritis

Chronic gastritis with Stomach Cold

Diaphragm Pain

Postoperative or post-illness diaphragm spasm

Morning Sickness

Morning sickness with cold-deficiency presentation

Chemotherapy Side Effects

Chemotherapy-induced nausea and hiccups

What This Formula Does

Every TCM formula has a specific set of actions — here's what Ding Xiang Shi Di Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Ding Xiang Shi Di Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Ding Xiang Shi Di Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Ding Xiang Shi Di Tang works at the root level.

This formula addresses hiccup (呃逆, è nì) arising from a pattern of Stomach Qi deficiency combined with internal Cold. In TCM, the Stomach's natural direction of Qi movement is downward. When the middle burner (the Spleen-Stomach system responsible for digestion) becomes deficient and Cold settles in the Stomach, this downward flow is disrupted. Cold, by its nature, constricts and obstructs, causing Stomach Qi to rebel upward instead of descending. The result is persistent hiccup — short, rapid, involuntary sounds that the person cannot control — often accompanied by a stifling sensation in the chest and upper abdomen.

The underlying deficiency is important: the Stomach lacks the warmth and strength to maintain its normal descending function. Cold may come from dietary factors (eating too much cold or raw food), constitutional weakness, or loss of Yang Qi after prolonged illness. Because the root cause involves both weakness (Qi deficiency) and a pathogenic factor (Cold), effective treatment must address both simultaneously — warming away the Cold while replenishing the Stomach's Qi so it can resume its proper downward movement.

The classical text Chéng Fāng Biàn Dú makes clear that although hiccup can be caused by either Heat or Cold, it always involves the Stomach failing to send Qi downward. This formula specifically targets the Cold-deficiency pattern, which is why it is strictly contraindicated when hiccup arises from Stomach Heat.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly acrid (pungent) and bitter — acrid to disperse Cold and move Qi downward, bitter to direct descent and check the rebellious upward flow of Stomach Qi, with a sweet undertone from Ren Shen to gently tonify.

Channels Entered

Ingredients

4 herbs

The herbs that make up Ding Xiang Shi Di Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Kings — Main ingredient driving the formula
Ding Xiang

Ding Xiang

Clove

Dosage 3 - 6g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs, Kidneys

Role in Ding Xiang Shi Di Tang

Warms the Stomach, dispels Cold, and powerfully directs Qi downward to stop hiccups and belching. As a key herb for Stomach Cold with rebellious Qi, it addresses the core pathomechanism of this formula.
Shi Di

Shi Di

Persimmon calyx

Dosage 6 - 9g
Temperature Neutral
Taste Bitter (苦 kǔ), Astringent (涩 sè)
Organ Affinity Stomach

Role in Ding Xiang Shi Di Tang

The principal herb for stopping hiccups and belching by directing rebellious Stomach Qi downward. Paired with Ding Xiang, the two form a classic combination that is considered the most effective pair for treating hiccups due to Stomach Cold.
Deputy — Assists and enhances the King
Ren Shen

Ren Shen

Ginseng root

Dosage 3 - 6g
Temperature Slightly Warm
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Spleen, Lungs, Heart, Kidneys

Role in Ding Xiang Shi Di Tang

Strongly tonifies Qi and nourishes the Stomach, addressing the underlying deficiency that allows Cold to accumulate. Without sufficient Stomach Qi, the descending function cannot be restored, so Ren Shen provides the foundation for lasting recovery.
Assistant — Supports or moderates other herbs
Sheng Jiang

Sheng Jiang

Fresh ginger rhizome

Dosage 6 - 9g
Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Spleen, Stomach

Role in Ding Xiang Shi Di Tang

Warms the Stomach, assists in directing rebellious Qi downward, and harmonizes the formula. Known as a premier herb for treating nausea and vomiting, it reinforces the warming and descending actions of Ding Xiang and Shi Di.

Why This Combination Works

How the herbs in Ding Xiang Shi Di Tang complement each other

Overall strategy

This formula treats persistent hiccups caused by Cold lodging in a weakened Stomach, where the Stomach's natural downward-moving function has reversed. The prescription strategy embeds warming and Qi-tonifying actions within a framework of descending rebellious Qi, so that the root cause (deficiency-Cold) and the main symptom (upward-surging Qi) are addressed simultaneously.

King herbs

Ding Xiang (Clove) and Shi Di (Persimmon Calyx) jointly serve as King herbs. Ding Xiang is acrid and warm, entering the Spleen, Stomach, and Kidney channels. It excels at warming the middle and directing Qi downward, making it the primary herb for Stomach Cold with rebellious Qi. Shi Di is bitter, astringent, and slightly warm, entering the Stomach channel, and is recognized as the single most specific herb for stopping hiccups. Together they form a renowned pairing: Ding Xiang provides the warming force to dispel Cold, while Shi Di provides the astringent, descending force to anchor Qi back down.

Deputy herbs

Ren Shen (Ginseng) serves as Deputy. The hiccups in this pattern arise not just from Cold but from underlying Stomach Qi deficiency that leaves the organ unable to maintain its normal descending function. Ren Shen powerfully tonifies Qi and strengthens the Stomach, ensuring the organ has the functional capacity to hold Qi in its proper downward direction once Cold has been dispersed.

Assistant herbs

Sheng Jiang (Fresh Ginger) is a reinforcing Assistant. Called the "sage herb for nausea" in classical literature, it amplifies the warming and descending actions of the two King herbs. Its acrid warmth further dispels Cold from the Stomach while its well-known anti-nausea effect addresses any accompanying vomiting or nausea.

Notable synergies

The Ding Xiang and Shi Di pairing is the formula's signature: one warms and mobilizes, the other astringes and descends, creating a focused descending action that neither herb achieves as effectively alone. The Ren Shen and Sheng Jiang pairing echoes the classical strategy of combining Qi-tonifying herbs with warming, harmonizing herbs to rebuild Stomach function from the ground up.

How to Prepare

Traditional preparation instructions for Ding Xiang Shi Di Tang

Place all four herbs in a ceramic, glass, or stainless steel pot (avoid aluminium, iron, or copper). Add approximately 400 ml (about 2 cups) of water. Bring to a boil, then reduce to a gentle simmer and cook for 20 to 30 minutes until roughly half the liquid remains. Strain and drink warm. Take one dose per day, divided into two servings (morning and evening), on an empty stomach or between meals. Serve warm, as the formula is intended to warm the Stomach and Cold conditions respond best to warm administration.

Common Modifications

How practitioners adapt Ding Xiang Shi Di Tang for specific situations

Added
Rou Gui

3-6g, powerfully warms Yang and dispels deep Cold

Wu Zhu Yu

3-6g, warms the Stomach and Liver, disperses Cold and descends Qi

When Cold is severe enough to produce cold extremities and a deep thin pulse, the base formula's warming power needs reinforcement. Rou Gui and Wu Zhu Yu provide stronger warming and Yang-supporting action to address deeper Cold accumulation.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Ding Xiang Shi Di Tang should not be used or requires extra caution

Avoid

Hiccup or vomiting due to Stomach Heat (symptoms such as loud forceful hiccups, bad breath, thirst for cold drinks, red tongue with yellow coating, rapid pulse). This formula is warm in nature and would worsen Heat conditions.

Avoid

Hiccup caused by Liver Qi stagnation transforming into Fire, or Yin-deficiency Fire flaring upward. The warming and drying herbs in this formula can further damage Yin and intensify Fire.

Caution

Severe Qi collapse or Kidney Yang collapse with hiccup (characterized by continuous faint hiccups, profuse sweating, cold extremities, fading pulse). As noted in the Yi Fang Lun, such cases require heavy doses of Ren Shen and Fu Zi to rescue Yang, which is beyond the scope of Ding Xiang and Shi Di.

Caution

Chronic illness with severe Qi and Yin deficiency following childbirth or prolonged disease. Use with caution and only with appropriate modifications to avoid further depleting Yin fluids with warm, drying herbs.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Ding Xiang (Cloves) is warm and acrid with Qi-moving properties, and while it is not a classical abortifacient, its warming and descending nature could theoretically stimulate uterine activity. Ren Shen (Ginseng) is generally considered safe in pregnancy at moderate doses, and Sheng Jiang (Fresh Ginger) is widely used for pregnancy-related nausea. Overall, this formula is not absolutely contraindicated in pregnancy, but should only be used under professional guidance when the pattern clearly calls for it. If hiccup in pregnancy involves any Heat signs, this formula is inappropriate.

Breastfeeding

Generally considered compatible with breastfeeding when used at standard doses for short durations. Ding Xiang (Cloves) contains eugenol, which in large amounts could theoretically transfer through breast milk, though at typical decoction doses this is not a significant concern. Ren Shen (Ginseng) and Sheng Jiang (Fresh Ginger) are widely consumed during the postpartum period in East Asian traditions. No specific adverse effects on lactation or nursing infants have been documented for this formula. Nevertheless, use should be supervised by a qualified practitioner, and the formula should be discontinued once hiccup resolves.

Children

This formula can be used in children, but dosage must be significantly reduced according to age and body weight. A common approach is to use one-third to one-half the adult dose for children aged 6 to 12, and one-quarter or less for children under 6. Ren Shen (Ginseng) should be used cautiously in young children, and Dang Shen (Codonopsis) is often substituted at double or triple the dose as a gentler Qi tonic. The warm, acrid nature of Ding Xiang and Sheng Jiang means the formula should only be used in pediatric cases with clear signs of Cold (pale tongue, cold limbs, preference for warmth) and not for hiccup with any Heat signs. Treatment duration should be kept short.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Ding Xiang Shi Di Tang

Anticoagulant and antiplatelet medications: Ding Xiang (Cloves) contains eugenol and acetyl eugenol, which have demonstrated antiplatelet activity in laboratory studies. Concurrent use with warfarin, heparin, aspirin, clopidogrel, or other blood-thinning medications may theoretically increase bleeding risk. Patients on anticoagulant therapy should inform their prescriber before using this formula.

Ginseng and warfarin: Ren Shen (Ginseng) has been reported in case studies to modestly decrease the anticoagulant effect of warfarin (lowering INR), potentially reducing its effectiveness. This creates a complex picture when combined with clove's opposing antiplatelet effect, making the net impact on coagulation unpredictable. Close INR monitoring is advised for patients on warfarin.

Hypoglycemic agents: Both Ren Shen and Ding Xiang have been associated with mild blood-sugar-lowering effects in some studies. Patients taking insulin or oral hypoglycemic agents (metformin, sulfonylureas) should monitor blood glucose more closely when using this formula.

Usage Guidance

Practical advice for getting the most out of Ding Xiang Shi Di Tang

Best time to take

30 minutes before meals, served warm, 2–3 times daily. If hiccup is severe, can also be taken in small, frequent sips between meals.

Typical duration

Acute use: 3–7 days, reassessed once hiccup resolves or significantly improves. Not intended for long-term use.

Dietary advice

Avoid cold, raw, and icy foods and beverages while taking this formula, as these can introduce further Cold into the Stomach and directly counteract the warming action of the herbs. Greasy, heavy, and difficult-to-digest foods should also be limited, as they can obstruct Stomach Qi and worsen the stifling sensation in the chest. Favour warm, easily digested foods such as congee, cooked vegetables, soups, and mild broths. Small, frequent meals are preferable to large ones. Spicy or overly hot foods should be consumed in moderation to avoid overstimulating an already disrupted Stomach.

Ding Xiang Shi Di Tang originates from Zhèng Yīn Mài Zhì (症因脈治) by Qín Jǐngmíng (秦景明) Míng dynasty (written ~1641 CE), published Qīng dynasty, 1706 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Ding Xiang Shi Di Tang and its clinical use

《成方便读》(Chéng Fāng Biàn Dú) by Zhang Bingcheng

"夫呃逆一证,其声短促,连续不断之象,虽其证有火有寒,皆能所致,然无不皆自胃腑而来者,以胃气下行为顺,上行为逆。"

Translation: "The condition of hiccup is characterised by short, rapid sounds occurring continuously. Although it can arise from either Fire or Cold, it invariably originates from the Stomach, because Stomach Qi descending is the normal direction — ascending is rebellious."

《成方便读》continued

"方中以丁香温胃祛寒,补火生土;柿蒂苦温降气,生姜散逆疏邪,二味皆胃经之药;用人参者,以祛邪必先补正,然后邪退正安。"

Translation: "In this formula, Ding Xiang warms the Stomach and expels Cold, supporting Fire to nourish Earth; Shi Di, bitter and warm, directs Qi downward; Sheng Jiang disperses the rebellious Qi and expels pathogenic factors — both target the Stomach channel. Ren Shen is included because to expel pathogenic factors one must first support the upright Qi, and only then can the pathogen retreat and the body find peace."

《医方论》(Yī Fāng Lùn) by Fei Boxiong

"若因寒犯胃,气郁而呃者,则此方为宜。"

Translation: "If the hiccup is caused by Cold invading the Stomach and Qi becoming constrained, then this formula is appropriate."

Historical Context

How Ding Xiang Shi Di Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Ding Xiang Shi Di Tang is recorded in the Zhèng Yīn Mài Zhì (《症因脉治》, "Pattern, Cause, Pulse, and Treatment"), a work by the Ming dynasty physician Qín Jǐngmíng (秦景明). The text is notable for its systematic approach of linking symptoms to their underlying causes, then identifying the corresponding pulse and treatment — a method reflected in the book's title. The formula's elegant simplicity of just four herbs became a model for treating Cold-type hiccup with concurrent Qi deficiency.

The combination of Ding Xiang and Shi Di for hiccup has deeper roots, however. Earlier formulas using these two herbs appear in the Jì Shēng Fāng (《济生方》, "Formulas to Aid the Living") by Yan Yonghe of the Song dynasty, where a simpler two-herb version called Shi Di Tang (柿蒂汤) consisting of Ding Xiang and Shi Di was used for hiccup without significant Qi deficiency. The addition of Ren Shen and Sheng Jiang in Ding Xiang Shi Di Tang specifically addressed cases where the patient's constitutional Qi was weakened. Later texts offered expanded versions: the Huí Chūn (《回春》) version added many more warming and aromatic herbs for severe Cold patterns, while the Shòu Shì Bǎo Yuán (《寿世保元》) version incorporated Fu Ling and Chen Pi for patients with concurrent Dampness and Phlegm. Qing dynasty commentators such as Zhang Bingcheng in the Chéng Fāng Biàn Dú and Fei Boxiong in the Yī Fāng Lùn both offered detailed analyses of the formula's rationale, helping to cement its place as the standard prescription for Cold-deficiency hiccup.