Dang Gui Shao Yao San

Dang Gui and Peony Powder · 當歸芍藥散

Also known as: Dang Gui Shao Yao Tang (当归芍药汤), Dang Gui Fu Ling San (当归茯苓散), Toki-shakuyaku-san (TJ-23, Japanese name),

A classical formula originally designed for women experiencing abdominal pain during pregnancy or menstruation, caused by a combination of Blood deficiency and internal Dampness. It nourishes and moves the Blood, supports healthy digestion, and resolves fluid retention, making it helpful for dull abdominal cramping, bloating, dizziness, swelling, and irregular periods.

Origin Jin Gui Yao Lue (Essential Prescriptions from the Golden Cabinet) by Zhang Zhongjing — Han dynasty, ~200 CE
Composition 6 herbs
Bai Shao
King
Bai Shao
Dang Gui
Deputy
Dang Gui
Chuan Xiong
Deputy
Chuan Xiong
Fu Ling
Assistant
Fu Ling
Bai Zhu
Assistant
Bai Zhu
Ze Xie
Assistant
Ze Xie
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Dang Gui Shao Yao San is designed to correct these specific patterns.

Why Dang Gui Shao Yao San addresses this pattern

When the Liver lacks sufficient Blood, it loses its ability to maintain smooth flow of Qi and becomes prone to constraint. This manifests as dull, cramping abdominal pain that comes and goes. Bai Shao, as the King herb at high dosage, directly nourishes Liver Blood and relaxes spasms. Dang Gui further supplements the Blood while Chuan Xiong ensures it circulates freely. The Blood-nourishing triad restores the Liver's suppleness, relieving the root cause of the pain and associated symptoms like dizziness, pallor, and irregular menstruation.

A practitioner would look for one or more of these signs

Abdominal Pain

Dull, cramping lower abdominal pain that waxes and wanes

Dizziness

Dizziness and lightheadedness from Blood deficiency

Severe Heart Palpitations

Palpitations due to Blood failing to nourish the Heart

Dull Pale Complexion

Pale or sallow complexion

Irregular Menstruation

Scanty or irregular periods

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Dang Gui Shao Yao San when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

TCM understands menstrual pain through the principle 'when there is no free flow, there is pain.' In many women, the pain is not caused by excess or cold alone, but by an insufficiency of Blood that deprives the uterus and Liver channel of nourishment. When Blood is deficient, the Liver loses its ability to ensure smooth circulation, leading to Qi and Blood stagnation in the lower abdomen during menstruation. At the same time, if the Spleen is weak, Dampness accumulates in the pelvic region, further obstructing the free flow of Blood. The result is dull, pulling, cramping pain (not the sharp, stabbing pain of full Blood stasis) that often comes with fatigue, dizziness, and a feeling of heaviness.

Why Dang Gui Shao Yao San Helps

Dang Gui Shao Yao San addresses menstrual pain from both the Blood and fluid sides simultaneously. Bai Shao in its large dose directly relaxes uterine cramping and smooths Liver Qi. Dang Gui and Chuan Xiong nourish and invigorate Blood to resolve the mild stagnation causing pain. Meanwhile, Fu Ling, Bai Zhu, and Ze Xie drain Dampness from the pelvic region, reducing congestion and swelling that contribute to the discomfort. Modern pharmacological research has shown the formula can improve blood flow, reduce prostaglandin F2-alpha levels, and inhibit platelet aggregation, offering scientific support for its clinical effectiveness in dysmenorrhea.

Also commonly used for

Irregular Menstruation

Associated with Liver-Spleen disharmony

Ovarian Cysts

Functional cysts with underlying Dampness and Blood stagnation

Edema

Pregnancy-related or premenstrual edema

Chronic Pelvic Inflammatory Disease

With dull pain and Dampness

Meniere's Disease

Dizziness with fluid retention

Infertility

Due to Liver-Spleen disharmony with Blood deficiency

Anemia

Mild anemia with Blood deficiency pattern

Abdominal Pain

Chronic dull abdominal pain without structural cause

Premenstrual Syndrome

Bloating, mood changes, and pain before periods

What This Formula Does

Every TCM formula has a specific set of actions — here's what Dang Gui Shao Yao San does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Dang Gui Shao Yao San is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Dang Gui Shao Yao San performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Dang Gui Shao Yao San works at the root level.

This formula addresses a pattern in which two interrelated problems reinforce each other: Blood deficiency in the Liver and Dampness accumulation due to Spleen weakness. In TCM, the Liver stores Blood and governs the smooth flow of Qi, while the Spleen transforms and transports fluids. When Liver Blood becomes insufficient — from menstruation, pregnancy, chronic illness, or constitutional weakness — the Liver loses its softness and flexibility. A Blood-deficient Liver tends toward tension and constraint, which is why the pain it produces is a dull, cramping, continuous ache rather than a sharp or stabbing sensation.

When the constrained Liver "overacts" on the Spleen (a recognized pathological direction in Five Phase theory, where Wood overwhelms Earth), the Spleen's ability to transform and transport fluids deteriorates. Fluids that should be metabolized accumulate as internal Dampness. This Dampness further obstructs the flow of Qi and Blood in the lower abdomen and uterus, worsening the pain and creating symptoms like edema, scanty urination, heaviness, and a white greasy tongue coating. The two problems create a vicious cycle: Blood deficiency makes the Liver tense and overbearing; the overbearing Liver weakens the Spleen; the weakened Spleen generates Dampness; and the Dampness further impedes Blood circulation.

During pregnancy, this mechanism is especially relevant. The body's Blood is directed toward nourishing the fetus, leaving less available for the Liver. The growing uterus and the metabolic demands of pregnancy also tax the Spleen's fluid-processing capacity. This is why Zhang Zhongjing placed this formula in both the pregnancy chapter and the general gynecological chapter of the Jin Gui Yao Lue — the same Liver-Spleen disharmony with Blood deficiency and Dampness accumulation underlies pain in both contexts.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Warm

Taste Profile

Predominantly sweet and bitter with a sour note — sweet from Bai Zhu and Fu Ling to tonify and harmonize, bitter from Bai Shao and Dang Gui to nourish Blood, and bland from Ze Xie and Fu Ling to drain Dampness through urination.

Channels Entered

Liver Spleen Kidney Bladder

Ingredients

6 herbs

The herbs that make up Dang Gui Shao Yao San, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
King — Main ingredient driving the formula
Bai Shao

Bai Shao

White peony root

Dosage 15 - 30g
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen

Role in Dang Gui Shao Yao San

Used in a dominant dose (far exceeding the other herbs), Bai Shao softens the Liver, relieves spasmodic abdominal pain, nourishes Blood, and restrains Liver Qi from overacting on the Spleen. It is the principal herb addressing the core complaint of cramping abdominal pain.
Deputies — Assists and enhances the King
Dang Gui

Dang Gui

Chinese Angelica root

Dosage 6 - 10g
Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen

Role in Dang Gui Shao Yao San

Nourishes and harmonizes the Blood, addressing the underlying Blood deficiency. Works with Bai Shao and Chuan Xiong to form the Blood-regulating core of the formula, supplementing the Liver's Blood stores while gently promoting circulation to relieve pain.
Chuan Xiong

Chuan Xiong

Szechuan lovage rhizome

Dosage 6 - 15g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium

Role in Dang Gui Shao Yao San

Invigorates Blood and promotes the movement of Qi. As a warm, acrid herb, it ensures that the Blood-nourishing action of Dang Gui and Bai Shao does not stagnate, and it facilitates smooth flow of Qi and Blood to resolve pain.
Assistants — Supports or moderates other herbs
Fu Ling

Fu Ling

Poria

Dosage 9 - 12g
Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys

Role in Dang Gui Shao Yao San

Strengthens the Spleen and promotes urination to drain Dampness. Supports the Spleen's ability to transform and transport fluids, addressing the internal accumulation of Dampness that contributes to pain and edema.
Bai Zhu

Bai Zhu

White Atractylodes rhizome

Dosage 9 - 12g
Temperature Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Spleen, Stomach

Role in Dang Gui Shao Yao San

Tonifies the Spleen Qi and dries Dampness. Works together with Fu Ling to restore the Spleen's transportation function, and is classically recognized for its ability to calm a restless fetus when Spleen Qi is deficient.
Ze Xie

Ze Xie

Water plantain rhizome

Dosage 9 - 15g
Temperature Cold
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Kidneys, Urinary Bladder

Role in Dang Gui Shao Yao San

Promotes urination and drains accumulated water and Dampness via the Bladder. Used in relatively large dosage alongside the Spleen-tonifying herbs, Ze Xie provides a direct outlet for fluid stagnation, clearing water retention from the lower body.

Why This Combination Works

How the herbs in Dang Gui Shao Yao San complement each other

Overall strategy

This formula addresses a pattern in which Blood deficiency and Liver constraint coexist with Spleen weakness and Dampness accumulation. The prescription simultaneously nourishes and moves Blood to relieve the Liver, while strengthening the Spleen and draining Dampness to resolve fluid stagnation. This dual approach of treating Blood and Water together (血水并治) is the hallmark of the formula.

King herb

Bai Shao (White Peony) is used at several times the dosage of any other herb, making it the undisputed King. Its sour, slightly cold nature softens and restrains the Liver, directly relaxing the cramping and spasmodic abdominal pain that defines this pattern. By restraining the Liver, it also prevents the Liver from overacting on the Spleen, laying the groundwork for the Spleen-supporting herbs to take effect.

Deputy herbs

Dang Gui and Chuan Xiong serve as Deputies. Dang Gui nourishes and supplements Blood, addressing the root deficiency, while Chuan Xiong invigorates Blood circulation and moves Qi. Together with Bai Shao, these three herbs form the blood-regulating triad (closely related to the later Si Wu Tang), ensuring that Blood is both replenished and kept moving freely so stagnation does not worsen pain.

Assistant herbs

Fu Ling, Bai Zhu, and Ze Xie form the Dampness-resolving group. Fu Ling (reinforcing assistant) strengthens the Spleen and gently promotes urination. Bai Zhu (reinforcing assistant) tonifies Spleen Qi and dries internal Dampness. Ze Xie (reinforcing assistant) provides a strong downward drainage of accumulated water through the urinary tract. Together, they restore the Spleen's fluid metabolism and resolve the water retention that compounds the abdominal pain and causes edema and dizziness.

Notable synergies

The pairing of Bai Shao with Bai Zhu is a classic Liver-Spleen combination: Bai Shao softens the Liver while Bai Zhu strengthens the Spleen, mutually preventing the Liver from overcontrolling a weakened Spleen. The interplay between the Blood group (Dang Gui, Bai Shao, Chuan Xiong) and the Water group (Fu Ling, Bai Zhu, Ze Xie) embodies the formula's distinctive principle that in gynecological conditions, Blood stasis and fluid retention often coexist and must be treated simultaneously.

How to Prepare

Traditional preparation instructions for Dang Gui Shao Yao San

The original text instructs: grind the six herbs into a fine powder. Take one square-inch spoonful (approximately 1.5–3g) of the powder, mix with warm rice wine, and take three times daily.

In modern clinical practice, this formula is most commonly prepared as a decoction (water decoction) instead. Combine all six herbs with approximately 1100ml of water, bring to a boil, then reduce to a gentle simmer for 30–40 minutes. Strain to obtain roughly 300ml of liquid and divide into 2–3 warm doses taken throughout the day.

Common Modifications

How practitioners adapt Dang Gui Shao Yao San for specific situations

Added
Gan Cao

Zhi Gan Cao (honey-prepared licorice) 6g, to relax spasms and moderate pain through its sweet, relaxing nature

Adding Gan Cao follows the classical Shao Yao Gan Cao Tang principle, where the pairing of Bai Shao with Gan Cao powerfully relaxes smooth muscle spasm and alleviates acute cramping pain.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Dang Gui Shao Yao San should not be used or requires extra caution

Caution

Abdominal pain due to excess Heat or true Blood stasis with fixed, stabbing pain and dark clots. This formula is designed for deficiency-type dull pain with Dampness, not for acute excess conditions requiring strong Blood-breaking or Heat-clearing formulas.

Caution

Severe Yin deficiency with empty Heat signs (night sweats, malar flush, dry mouth, red tongue with no coat). The drying and draining herbs (Bai Zhu, Ze Xie, Fu Ling) may further deplete fluids in a genuinely Yin-deficient patient.

Avoid

Active hemorrhage or heavy menstrual bleeding. Dang Gui and Chuan Xiong invigorate Blood circulation, which could worsen active bleeding.

Caution

Concurrent use with anticoagulant or antiplatelet medications (e.g. warfarin, aspirin, clopidogrel) without medical supervision, due to potential additive anticoagulant effects from Dang Gui and Chuan Xiong.

Caution

Cold-type abdominal pain with pronounced cold signs (severe cold limbs, desire for warmth, pale complexion, deep slow pulse) that requires strong warming herbs. This formula is only mildly warm and lacks strong Yang-warming herbs.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

This formula is classically indicated for use during pregnancy and has been used for abdominal pain in pregnant women for nearly two thousand years. Zhang Zhongjing originally described it specifically for pregnancy-related cramping pain, and it is renowned in the Japanese Kampo tradition for its safety during pregnancy, often prescribed to "stabilize the fetus." However, Chuan Xiong (Ligusticum chuanxiong) is a Blood-invigorating herb with a dispersing nature, and classical commentators advise keeping its dosage conservative during pregnancy to avoid excessive Qi dispersal. In modern clinical practice, this formula is generally considered safe during pregnancy when used at standard doses under professional guidance, but dosage of Chuan Xiong should be moderated (typically 6-10g rather than higher doses). Pregnant women should always consult a qualified practitioner before use.

Breastfeeding

Dang Gui Shao Yao San is generally considered compatible with breastfeeding. All six herbs are commonly used in postpartum recovery formulas to nourish Blood and restore Spleen function after delivery. None of the herbs in this formula are known to be toxic or to produce harmful compounds that transfer through breast milk in clinically significant amounts. Dang Gui has traditionally been used to support postpartum recovery and lactation. However, as with any herbal formula during breastfeeding, use should be supervised by a qualified practitioner, and any changes in the infant's feeding behavior or health should be monitored.

Children

Dang Gui Shao Yao San is primarily a gynecological formula and is rarely indicated in pediatric practice. Its main indications (menstrual pain, pregnancy-related conditions, Liver-Spleen disharmony with Blood deficiency and Dampness) are not common presentations in children. If used in adolescents for menstrual-related complaints after menarche, dosages should be reduced to approximately one-half to two-thirds of the standard adult dose, adjusted by body weight and constitution. Use in young children is not standard practice and should only occur under close supervision by a qualified practitioner with specific clinical justification.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Dang Gui Shao Yao San

Anticoagulants and antiplatelet drugs (warfarin, heparin, aspirin, clopidogrel): Dang Gui (Angelica sinensis) contains natural coumarin derivatives and ferulic acid, which can inhibit platelet aggregation and thromboxane formation. Animal studies and case reports have documented that Dang Gui can potentiate the anticoagulant effect of warfarin, increasing INR and bleeding risk. Chuan Xiong (Ligusticum chuanxiong) also possesses antiplatelet properties. Patients on anticoagulant or antiplatelet therapy should inform their physician before using this formula, and INR should be monitored more closely if concurrent use is necessary.

Diuretics: Ze Xie (Alisma orientale), Fu Ling (Poria cocos), and Bai Zhu (Atractylodes macrocephala) all promote urination and fluid metabolism. Combined use with pharmaceutical diuretics (furosemide, hydrochlorothiazide, spironolactone) could theoretically produce additive diuretic effects, potentially contributing to electrolyte imbalance or dehydration, though this has not been formally studied.

Hormone-sensitive conditions and hormonal medications: Dang Gui has demonstrated weak estrogenic activity in some studies. While clinical significance is debated, caution is advised in patients with hormone-sensitive conditions or those taking hormonal medications (oral contraceptives, hormone replacement therapy, tamoxifen).

Usage Guidance

Practical advice for getting the most out of Dang Gui Shao Yao San

Best time to take

Traditionally taken three times daily with warm rice wine; in modern practice, taken twice daily 30 minutes before meals on a relatively empty stomach to enhance absorption.

Typical duration

Typically prescribed for 2-8 weeks for menstrual pain or gynecological conditions, reassessed monthly; may be taken throughout pregnancy under practitioner supervision for pregnancy-related abdominal pain.

Dietary advice

While taking this formula, favor warm, easily digestible, nourishing foods that support both Blood and Spleen function: cooked grains (rice, millet, oats), root vegetables, dark leafy greens, small amounts of lean protein, and warming soups. Foods that traditionally nourish Blood such as red dates, goji berries, and black sesame are beneficial. Avoid cold, raw foods (salads, ice cream, cold drinks, raw sushi) and greasy, heavy, or overly rich foods, as these further burden the Spleen and generate more Dampness — exactly what this formula is trying to resolve. Excessive dairy, sugar, and processed foods should also be minimized. The classical method of administration was with warm wine (酒和服), which helps promote circulation and enhance the formula's Blood-moving function.

Dang Gui Shao Yao San originates from Jin Gui Yao Lue (Essential Prescriptions from the Golden Cabinet) by Zhang Zhongjing Han dynasty, ~200 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Dang Gui Shao Yao San and its clinical use

Jin Gui Yao Lue (金匮要略), Chapter 20 — Pregnancy Diseases:
「妇人怀娠,腹中㽲痛,当归芍药散主之。」
"When a woman is pregnant and has cramping pain in the abdomen, Dang Gui Shao Yao San governs."

Jin Gui Yao Lue (金匮要略), Chapter 22 — Miscellaneous Diseases of Women:
「妇人腹中诸疾痛,当归芍药散主之。」
"For all types of abdominal pain in women, Dang Gui Shao Yao San governs."

Jin Gui Yao Lue Lun Zhu (金匮要略论注) by Xu Bin:
「㽲痛者,绵绵而痛,不若寒疝之绞痛,血气之刺痛也。正气乃不足,使阴得乘阳,而水气胜土,脾郁不伸。」
"This cramping pain is a continuous dull ache, unlike the twisting pain of cold hernia or the stabbing pain of Blood stagnation. The upright Qi is insufficient, allowing Yin to overwhelm Yang, water overcoming Earth, so the Spleen is suppressed and cannot extend freely."

Jin Gui Yao Lue Xin Dian (金匮要略心典) by You Yi:
「妇人以血为主,而血以中气为主。中气者,土气也。土燥不生物,土湿亦不生物。芍药、芎、归滋其血,苓、术、泽泻治其湿,燥湿得宜,而土能生物,疾痛并蠲矣。」
"In women, Blood is paramount, and Blood depends on the Middle Qi. Middle Qi is the Qi of Earth. Earth that is too dry cannot nourish life; Earth that is too damp also cannot nourish life. Shao Yao, Xiong, and Gui nourish the Blood; Ling, Zhu, and Ze Xie treat the Dampness. When dryness and dampness are properly balanced, Earth can nourish life and all pains are resolved."

Historical Context

How Dang Gui Shao Yao San evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Dang Gui Shao Yao San originates from Zhang Zhongjing's Jin Gui Yao Lue (Essentials from the Golden Cabinet), compiled around 220 CE during the late Han Dynasty. It appears in two separate chapters: Chapter 20 on pregnancy diseases, for cramping abdominal pain during pregnancy, and Chapter 22 on miscellaneous diseases of women, for general abdominal pain. This dual placement reflects the formula's broad applicability to gynecological conditions rooted in Liver-Spleen disharmony.

An intriguing historical note comes from the Yuan He Ji Yong Jing (元和纪用经), which records an earlier form of this prescription as a longevity and health-cultivation formula attributed to the Daoist immortal An Qi Xian Sheng, who supposedly gave it to Li Shao Jun. According to this account, Zhang Zhongjing later modified it for pregnancy abdominal pain. The formula was also known by the alias Liu Qi Jing Wei Wan (六气经纬丸, "Six Qi Warp and Weft Pill") in its pill form. Later generations often regarded it as an important precursor to Si Wu Tang (Four Substance Decoction), the foundational Blood-nourishing formula, since three of its six herbs (Dang Gui, Bai Shao, Chuan Xiong) form the core of Si Wu Tang. The Song Dynasty text San Yin Fang praised it for regular use, stating it could "free the flow of Blood vessels, eliminate disease, nourish the Stomach, brighten the eyes, and generate fluids." Some later scholars have also argued that the famous Xiao Yao San (Free Wanderer Powder) was developed using this formula as a blueprint.

In Japan, the formula is known as Toki-shakuyaku-san (TJ-23) and remains one of the most widely prescribed Kampo formulas, particularly in obstetrics and gynecology. Japanese clinicians have significantly expanded its modern applications to include dementia and cognitive disorders, sparking an international line of research into its neuroprotective properties.

Modern Research

4 published studies investigating the pharmacological effects or clinical outcomes of Dang Gui Shao Yao San

1

Systematic Review and Meta-Analysis: Danggui-Shaoyao-San for Dementia (2020)

Kim Y, Cho SH. Medicine. 2020;99(4):e18507.

This systematic review pooled data from 9 randomized controlled trials examining the formula's effects on Alzheimer's disease (AD) and vascular dementia (VD). The analysis found that the formula showed significant improvements on cognitive scales (MMSE) and activities of daily living compared with vitamin E in AD patients, and was superior to nootropic drugs for VD patients. However, included studies were small and some had methodological limitations.

PubMed
2

In Vitro Study: Antioxidant and Antiplatelet Effects on Human Blood Cells (2005)

Hsu HY et al. American Journal of Chinese Medicine. 2005;33(5):747-767.

This laboratory study tested the formula's effects on human blood cells, finding concentration-dependent antioxidant activity including free radical scavenging, inhibition of superoxide formation, and anti-lipid peroxidation effects. The formula also demonstrated antiplatelet activity, providing a pharmacological basis for its traditional use in Blood-stasis conditions.

PubMed
3

Review Article: Danggui-Shaoyao-San: New Hope for Alzheimer's Disease (2016)

Fu X, Wang Q, Wang Z, Kuang H, Jiang P. Aging and Disease. 2016;7(4):502-513.

This review compiled preclinical evidence showing the formula possesses anti-inflammatory and antioxidant properties, reduces hippocampal cell apoptosis, modulates central monoamine neurotransmitter systems, and ameliorates dysfunction of the cholinergic nervous system. These properties suggest potential mechanisms for its observed neuroprotective effects in animal models of dementia.

4

Preclinical Study: DSS Ameliorates Cognitive Impairment in Vascular Dementia Rats via PI3K/Akt Pathway (2024)

Liu X, Yao L, Ye X, et al. Journal of Ethnopharmacology. 2024.

This animal study established a vascular dementia model using bilateral carotid artery ischemia-reperfusion in rats. The formula significantly reduced hippocampal cell damage and improved learning and memory ability. Mechanistically, it upregulated expression of PI3K and Akt proteins, suggesting neuroprotection through this signaling pathway.

PubMed

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.