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Achyranthes roots

Chinese: 牛膝

Pinyin: Niú Xī

Parts used: Dried root

TCM category: Herbs that invigorate the Blood

TCM nature: Neutral

TCM taste(s): BitterSour

Organ affinity: Kidney Liver

Scientific name: Achyranthes bidentata

Other names: Ox knee, Two-toothed achyranthes

Use of achyranthes roots (Niu Xi) in TCM

Please note that you should never self-prescribe TCM ingredients. A TCM ingredient is almost never eaten on its own but as part of a formula containing several ingredients that act together. Please consult a professional TCM practitioner, they will be best able to guide you.

Preparation: Remove impurities, wash, cut into sections and dry.

Dosage: 6 - 9 grams

Main actions according to TCM*: Moves Blood and relieves pain in the raw state. Tonic to the Liver and Kidneys and strengthens the bones and sinews. Reduces Damp-Heat in the Lower Burner. Regulates the flow of reckless Blood caused by either ascendant Liver Yang or Yin Deficient Fire.

Primary conditions or symptoms for which achyranthes roots may be prescribed by TCM doctors*: Amenorrhea Knee pain Irregular menstruation Back pain Hematuria Nosebleed Bloody sputum Headache Toothache

Contraindications*: Should not be used by pregnant women and should be used with caution by those with weak digestion and Spleen Deficiency.

Common TCM formulas in which achyranthes roots (Niu Xi) are used*

Du Huo Ji Sheng Tang

Source date: 650 AD

Number of ingredients: 15 herbs

Formula key actions: Anti-rheumatic, clears Wind, Cold and Damp Stagnation. Strengthens the function of the Liver and Kidney. Tonifies Qi and Blood.

Conditions targeted*: Chronic lower back painSciatica and others

Niu Xi is an assistant ingredient in Du Huo Ji Sheng Tang. This means that it either serves to reinforces the effect of other ingredients or it moderates their toxicity.

Read more about Du Huo Ji Sheng Tang

Zuo Gui Wan

Source date: 1624 AD

Number of ingredients: 8 herbs

Formula key actions: Nourishes the Yin. Strengthens the Kidneys. Fills the Essence. Augments the marrow.

Conditions targeted*: Chronic bronchitisChronic nephritis and others

Niu Xi is an assistant ingredient in Zuo Gui Wan. This means that it either serves to reinforces the effect of other ingredients or it moderates their toxicity.

In Zuo Gui Wan, Niu Xi augments the Liver and Kidneys, strengthens the back and knees, as well as builds the sinews and bones.

Read more about Zuo Gui Wan

Yu Nu Jian

Source date: 1624 AD

Number of ingredients: 5 herbs

Formula key actions: Drains Heat from the Stomach. Nourishes Yin.

Conditions targeted*: StomatitisGlossitis and others

Niu Xi is an envoy ingredient in Yu Nu Jian. This means that it directs the formula towards certain area of the body and/or harmonizes the actions of other ingredients.

In Yu Nu Jian, Niu Xi directs the Heat downward by guiding Blood downward and thereby stops Blood flowing into the oral cavity.

Read more about Yu Nu Jian

He Che Da Zao Wan

Number of ingredients: 11 herbs

Formula key actions: Tonifies the Kidneys. Strengthens the Directing and Penetrating Vessels. Regulates the periods.

Read more about He Che Da Zao Wan

Da Ying Jian

Source date: 1624 AD

Number of ingredients: 7 herbs

Formula key actions: Tonifies Qi and Blood. Expels Cold.

In Da Ying Jian, Niu Xi nourishes the Liver and invigorates Blood

Read more about Da Ying Jian

Dang Gui Di Huang Yin

Source date: 1640 AD

Number of ingredients: 7 herbs

Formula key actions: Nourishes Blood. Tonifies Kidney and Liver Yin. Regulates the menstrual cycle.

In Dang Gui Di Huang Yin, Niu Xi nourishes the Kidneys and strengthens the back and knees

Read more about Dang Gui Di Huang Yin

Key TCM concepts behind achyranthes roots (Niu Xi)'s properties

In Traditional Chinese Medicine (TCM), achyranthes roots are plants that belong to the 'Herbs that invigorate the Blood' category. Like the name indicates these herbs tend to stimulate the Blood flow. In TCM they're used to help the circulation of Blood in cardiovascular conditions or menstrual irregularities as well as to treat acute pains caused by Blood Stagnation. They can also be used to treat Blood Stagnation when it causes certain tumors, cysts and hardened clots.

Furthermore achyranthes roots are plants that are Neutral in nature. This means that achyranthes roots typically don't affect the balance in your body. Balance between Yin and Yang is a key health concept in TCM. Eating too many "Hot" (Yang) ingredients can lead to an imbalance whereby one has a Yang Excess. The inverse is true as well: too many "Cold" (Yin) ingredients can lead to a Yin Excess. The Neutral nature of achyranthes roots means that you don't have to worry about that!

Achyranthes roots also taste Bitter and Sour. The so-called 'Five Phases' theory in Chinese Medicine states that the taste of TCM ingredients is a key determinant of their action in the body. Bitter ingredients like achyranthes roots tend to have a cleansing action on the body by clearing Heat, drying Dampness and promoting elimination via urination or bowel movements. On the other hand Sour ingredients help with digestion and restrain abnormal discharges of Fluids from the body, such as diarrhea or heavy sweating.

The tastes of ingredients in TCM also determine what Organs and Meridians they target. As such achyranthes roots are thought to target the Kidney and the Liver. According to TCM, the Kidneys do not only regulate the urinary system but also play a key role in the reproductive system and the growth and aging process of the body. The Liver on the other hand is often referred as the body's "general" because it is in charge of regulating the movements of Qi and the Body Fluids. It also takes a leading role in balancing our emotions.

Research on achyranthes roots (Niu Xi)

Achyranthes bidentata polysaccharides (ABP), isolated from the root of Achyranthes bidentata Blume inhibited the growth of sarcoma 180 in mice and prolongated the survival days of mice bearing Ehrlich carcinoma.1

Sulfation of Achyranthes bidentata polysaccharide was shown to have high activity as anti-HBsAg and HBeAg. It is also effective on simple herpes virus type-I.2


1. Xiang DB, Li XY (1993). Antitumor activity and immuno-potentiating actions of Achyranthes bidentata polysaccharides. Zhongguo yao li xue bao = Acta Pharmacologica Sinica, 14(6):556-561

2. Tian GY, Li ST, Song ML, Zheng MS, Li W (1995). Synthesis of Achyranthes bidentata polysaccharide sulfate and its antivirus activity. Yao xue xue bao = Acta Pharmaceutica Sinic, 30(2):107-111.